scholarly journals Enablingin vivomeasurements of nanoparticle concentrations with three-dimensional optoacoustic tomography

2013 ◽  
Vol 7 (8) ◽  
pp. 581-588 ◽  
Author(s):  
Dmitri A. Tsyboulski ◽  
Anton V. Liopo ◽  
Richard Su ◽  
Sergey A. Ermilov ◽  
Sergei M. Bachilo ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Optoacoustic Tomography

Volumetric Real-Time Tracking of Peripheral Human Vasculature With GPU-Accelerated Three-Dimensional Optoacoustic Tomography

2013 ◽  
Vol 32 (11) ◽  
pp. 2050-2055 ◽  
Author(s):  
X. Luis Dean-Ben ◽  
Ali Ozbek ◽  
Daniel Razansky
Keyword(s):  
Real Time ◽  
Three Dimensional ◽  
Optoacoustic Tomography ◽  
Real Time Tracking

Three-dimensional optoacoustic mesoscopy of the tumor heterogeneity in vivo using high depth-to-resolution multispectral optoacoustic tomography

2017 ◽  
Author(s):  
Jiao Li ◽  
Songhe Zhang ◽  
Andrei Chekkoury ◽  
Sarah Glasl ◽  
Paul Vetschera ◽  
...  
Keyword(s):  
Tumor Heterogeneity ◽  
Three Dimensional ◽  
Optoacoustic Tomography ◽  
High Depth

scholarly journals Accelerating image reconstruction in three-dimensional optoacoustic tomography on graphics processing units

2013 ◽  
Vol 40 (2) ◽  
pp. 023301 ◽  
Author(s):  
Kun Wang ◽  
Chao Huang ◽  
Yu-Jiun Kao ◽  
Cheng-Ying Chou ◽  
Alexander A. Oraevsky ◽  
...  
Keyword(s):  
Image Reconstruction ◽  
Graphics Processing Units ◽  
Three Dimensional ◽  
Optoacoustic Tomography ◽  
Graphics Processing

scholarly journals Three-dimensional optoacoustic tomography at video rate

2012 ◽  
Vol 20 (20) ◽  
pp. 22712 ◽  
Author(s):  
A. Buehler ◽  
X. L. Deán-Ben ◽  
J. Claussen ◽  
V. Ntziachristos ◽  
D. Razansky
Keyword(s):  
Three Dimensional ◽  
Optoacoustic Tomography

Simultaneous visualization of tumour oxygenation, neovascularization and contrast agent perfusion by real-time three-dimensional optoacoustic tomography

2015 ◽  
Vol 26 (6) ◽  
pp. 1843-1851 ◽  
Author(s):  
Vladimir Ermolayev ◽  
Xose Luis Dean-Ben ◽  
Subhamoy Mandal ◽  
Vasilis Ntziachristos ◽  
Daniel Razansky
Keyword(s):  
Contrast Agent ◽  
Real Time ◽  
Three Dimensional ◽  
Optoacoustic Tomography ◽  
Tumour Oxygenation ◽  
Simultaneous Visualization

scholarly journals Bedside 3D Visualization of Lymphatic Vessels with a Handheld Multispectral Optoacoustic Tomography Device

2020 ◽  
Vol 9 (3) ◽  
pp. 815 ◽  
Author(s):  
Guido Giacalone ◽  
Takumi Yamamoto ◽  
Florence Belva ◽  
Akitatsu Hayashi
Keyword(s):  
Real Time ◽  
Near Infrared ◽  
3D Visualization ◽  
Imaging Modality ◽  
Three Dimensional ◽  
Lymphatic Vessels ◽  
Secondary Lymphedema ◽  
Optoacoustic Tomography ◽  
Small Vessels ◽  
Promising Tool

Identification of lymphatics by Indocyanine Green (ICG) lymphography in patients with severe lymphedema is limited due to the overlying dermal backflow. Nor can the method detect deep and/or small vessels. Multispectral optoacoustic tomography (MSOT), a real-time three- dimensional (3D) imaging modality which allows exact spatial identification of absorbers in tissue such as blood and injected dyes can overcome these hurdles. However, MSOT with a handheld probe has not been performed yet in lymphedema patients. We conducted a pilot study in 11 patients with primary and secondary lymphedema to test whether lymphatic vessels could be detected with a handheld MSOT device. In eight patients, we could not only identify lymphatics and veins but also visualize their position and contractility. Furthermore, deep lymphatic vessels not traceable by ICG lymphography and lymphatics covered by severe dermal backflow, could be clearly identified by MSOT. In three patients, two of which had advanced stage lymphedema, only veins but no lymphatic vessels could be identified. We found that MSOT can identify and image lymphatics and veins in real-time and beyond the limits of near-infrared technology during a single bedside examination. Given its easy use and high accuracy, the handheld MSOT device is a promising tool in lymphatic surgery.

Three-dimensional quantitative functional optoacoustic tomography to estimate vascular blood oxygenation of the breast

2021 ◽  
Author(s):  
Seonyeong Park ◽  
Umberto Villa ◽  
Frank J. Brooks ◽  
Richard Su ◽  
Alexander A. Oraevsky ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Blood Oxygenation ◽  
Optoacoustic Tomography

scholarly journals Discrete Imaging Models for Three-Dimensional Optoacoustic Tomography Using Radially Symmetric Expansion Functions

2014 ◽  
Vol 33 (5) ◽  
pp. 1180-1193 ◽  
Author(s):  
Kun Wang ◽  
Robert W. Schoonover ◽  
Richard Su ◽  
Alexander Oraevsky ◽  
Mark A. Anastasio
Keyword(s):  
Three Dimensional ◽  
Optoacoustic Tomography

scholarly journals Three-dimensional optoacoustic tomography using a conventional ultrasound linear detector array: Whole-body tomographic system for small animals

2012 ◽  
Vol 40 (1) ◽  
pp. 013302 ◽  
Author(s):  
Jérôme Gateau ◽  
Miguel Ángel Araque Caballero ◽  
Alexander Dima ◽  
Vasilis Ntziachristos
Keyword(s):  
Three Dimensional ◽  
Detector Array ◽  
Whole Body ◽  
Small Animals ◽  
Linear Detector ◽  
Optoacoustic Tomography ◽  
Conventional Ultrasound

scholarly journals Noninvasive Real-Time Visualization of Multiple Cerebral Hemodynamic Parameters in Whole Mouse Brains Using Five-Dimensional Optoacoustic Tomography

2015 ◽  
Vol 35 (4) ◽  
pp. 531-535 ◽  
Author(s):  
Sven Gottschalk ◽  
Thomas Felix Fehm ◽  
Xosé Luís Deán-Ben ◽  
Daniel Razansky
Keyword(s):  
Real Time ◽  
Cerebral Blood Volume ◽  
Functional Neuroimaging ◽  
Three Dimensional ◽  
Blood Oxygenation ◽  
Hemodynamic Parameters ◽  
Label Free ◽  
Optoacoustic Tomography ◽  
Real Time Visualization ◽  
Tomographic Data

Current functional neuroimaging methods are not adequate for high-resolution whole-brain visualization of neural activity in real time. Here, we show imaging of fast hemodynamic changes in deep mouse brain using fully noninvasive acquisition of five-dimensional optoacoustic data from animals subjected to oxygenation stress. Multispectral video-rate acquisition of three-dimensional tomographic data enables simultaneous label-free assessment of multiple brain hemodynamic parameters, including blood oxygenation, total hemoglobin, cerebral blood volume, oxygenized and deoxygenized hemoglobin, in real time. The unprecedented results indicate that the proposed methodology may serve as a powerful complementary, and potentially superior, method for functional neuroimaging studies in rodents.

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