Three-dimensional printing of poly(glycerol sebacate fumarate) gadodiamide-poly(ethylene glycol) diacrylate structures and characterization of mechanical properties for soft tissue applications

2018 ◽  
Vol 107 (3) ◽  
pp. 664-671 ◽  
Author(s):  
Prashanth Ravi ◽  
Jamie Wright ◽  
Panos S. Shiakolas ◽  
Tré R. Welch
Keyword(s):  
Mechanical Properties ◽  
Soft Tissue ◽  
Ethylene Glycol ◽  
Three Dimensional ◽  
Poly Ethylene Glycol ◽  
Three Dimensional Printing ◽  
Glycol Diacrylate ◽  
Poly Ethylene ◽  
Dimensional Printing

Preparation and characterization of crosslinked poly(ethylene glycol) diacrylate hydrogels as fouling-resistant membrane coating materials

2009 ◽  
Vol 330 (1-2) ◽  
pp. 180-188 ◽  
Author(s):  
Hao Ju ◽  
Bryan D. McCloskey ◽  
Alyson C. Sagle ◽  
Victor A. Kusuma ◽  
Benny D. Freeman
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Coating Materials ◽  
Glycol Diacrylate ◽  
Membrane Coating ◽  
Poly Ethylene

Characterization of UV-curable poly(ethylene glycol) diacrylate based hydrogels

2015 ◽  
Vol 31 (6) ◽  
pp. 1046-1050 ◽  
Author(s):  
Xuzhen Qin ◽  
Qianqian Hu ◽  
Guanghui Gao ◽  
Shuang Guan
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Uv Curable ◽  
Glycol Diacrylate ◽  
Poly Ethylene

Synthesis and characterization of poly(ethylene glycol) diacrylate copolymers containing azobenzene groups prepared by frontal polymerization

2011 ◽  
Vol 49 (15) ◽  
pp. 3291-3298 ◽  
Author(s):  
Javier Illescas ◽  
Yessica S. Ramirez-Fuentes ◽  
Ernesto Rivera ◽  
Omar G. Morales-Saavedra ◽  
Antonio A. Rodríguez-Rosales ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Frontal Polymerization ◽  
Synthesis And Characterization ◽  
Poly Ethylene Glycol ◽  
Glycol Diacrylate ◽  
Poly Ethylene ◽  
Azobenzene Groups

Culturing of transgenic mice liver tissue slices in three-dimensional microfluidic structures of PEG-DA (poly(ethylene glycol) diacrylate)

2013 ◽  
Vol 176 ◽  
pp. 1081-1089 ◽  
Author(s):  
Shilpa Sivashankar ◽  
Srinivasu Valegerahally Puttaswamy ◽  
Ling-Hui Lin ◽  
Tz-Shuian Dai ◽  
Chau-Ting Yeh ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Ethylene Glycol ◽  
Liver Tissue ◽  
Three Dimensional ◽  
Poly Ethylene Glycol ◽  
Tissue Slices ◽  
Glycol Diacrylate ◽  
Poly Ethylene ◽  
Mice Liver

scholarly journals Modulating Functionalized Poly(ethylene glycol) Diacrylate Hydrogel Mechanical Properties through Competitive Crosslinking Mechanics for Soft Tissue Applications

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3000
Author(s):  
Rachel Chapla ◽  
Mera Alhaj Abed ◽  
Jennifer West
Keyword(s):  
Soft Tissue ◽  
Ethylene Glycol ◽  
Soft Tissues ◽  
Monomer Concentration ◽  
Tissue Type ◽  
Poly Ethylene Glycol ◽  
Average Cell ◽  
Glycol Diacrylate ◽  
Average Percentage ◽  
Poly Ethylene

Local mechanical stiffness influences cell behavior, and thus cell culture scaffolds should approximate the stiffness of the tissue type from which the cells are derived. In synthetic hydrogels, this has been difficult to achieve for very soft tissues such as neural. This work presents a method for reducing the stiffness of mechanically and biochemically tunable synthetic poly(ethylene glycol) diacrylate hydrogels to within the soft tissue stiffness regime by altering the organization of the crosslinking sites. A soluble allyl-presenting monomer, which has a higher propensity for chain termination than acrylate monomers, was introduced into the PEG-diacrylate hydrogel precursor solution before crosslinking, resulting in acrylate-allyl competition and a reduction in gel compressive modulus from 5.1 ± 0.48 kPa to 0.32 ± 0.09 kPa. Both allyl monomer concentration and chemical structure were shown to influence the effectiveness of competition and change in stiffness. Fibroblast cells demonstrated a 37% reduction in average cell spread area on the softest hydrogels produced as compared to cells on control hydrogels, while the average percentage of neural cells extending neurites increased by 41% on these hydrogels, demonstrating the potential for this technology to serve as a soft tissue culture system.

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