Survival of a Jehovah's Witness with thrombotic thrombocytopenic purpura without using plasma: A case report and review of the literature

2019 ◽  
Vol 34 (5) ◽  
pp. 623-630
Author(s):  
Babak Baseri ◽  
Swati Vishwanathan ◽  
Daniel Benasher ◽  
Mikhail Khazan ◽  
Carol Luhrs ◽  
...  
Keyword(s):  
Case Report ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Review Of The Literature ◽  
Thrombocytopenic Purpura ◽  
Jehovah’S Witness ◽  
Jehovah's Witness

scholarly journals Successful Management of Thrombotic Thrombocytopenic Purpura in a Jehovah’s Witness: An Individualized Approach With Joint Decision-Making

2019 ◽  
Vol 7 (1) ◽  
pp. 8-11
Author(s):  
Ming Y Lim ◽  
Charles S Greenberg
Keyword(s):  
Decision Making ◽  
Replacement Therapy ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Blood Products ◽  
Thrombocytopenic Purpura ◽  
Joint Decision ◽  
Unique Challenge ◽  
Jehovah’S Witness ◽  
Jehovah's Witness ◽  
Individualized Approach

The management of thrombotic thrombocytopenic purpura (TTP) presents a unique challenge in individuals who are unable to accept plasma due to religious beliefs, given that therapeutic plasma exchange (TPE) is the standard of care. A 61-year-old Jehovah’s Witness woman presented to our hospital with neurological symptoms and laboratory findings suggestive of TTP. On admission, she refused transfusion of blood products, specifically red blood cells, platelets, and plasma but accepted albumin and intravenous immunoglobulin (IVIG); fractions of plasma. She was started on steroids, IVIG, and TPE with albumin as replacement therapy with minimal improvement. After a detailed discussion with the patient and family, they agreed to accept cryosupernatant. The patient started TPE with cryosupernatant for replacement therapy, which resulted in clinical improvement. This case highlights the importance of an individualized approach with joint decision-making given the significant heterogeneity that exists in Jehovah’s Witnesses’ attitude toward the receipt of blood products.

scholarly journals Thrombotic thrombocytopenic purpura induced by trimethoprim-sulfamethoxazole in a Jehovah's witness

2007 ◽  
Vol 82 (7) ◽  
pp. 679-681 ◽  
Author(s):  
Michael G. Martin ◽  
Nicole L. Whitlatch ◽  
Bijal Shah ◽  
Gowthami M. Arepally
Keyword(s):  
Thrombotic Thrombocytopenic Purpura ◽  
Thrombocytopenic Purpura ◽  
Jehovah’S Witness ◽  
Jehovah's Witness

scholarly journals Management of thrombotic thrombocytopenic purpura without plasma exchange: the Jehovah’s Witness experience

2017 ◽  
Vol 1 (24) ◽  
pp. 2161-2165 ◽  
Author(s):  
James N. George ◽  
Steven A. Sandler ◽  
Joanna Stankiewicz
Keyword(s):  
Plasma Exchange ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Jehovah’S Witnesses ◽  
Thrombocytopenic Purpura ◽  
Jehovah's Witnesses ◽  
Jehovah’S Witness ◽  
Jehovah's Witness ◽  
Key Points ◽  
The Future

Key Points TTP in Jehovah’s Witness patients has been managed successfully without PEX. This experience, plus new TTP treatments, may make it possible for patients who are not Jehovah’s Witnesses to avoid PEX in the future.

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