Transcriptom analysis revealed regulation of dexamethasone induced microRNAs in chicken thymus

2018 ◽  
Vol 120 (4) ◽  
pp. 6570-6579 ◽  
Author(s):  
Yanting Zhou ◽  
Weihua Tian ◽  
Meng Zhang ◽  
Tuanhui Ren ◽  
Guirong Sun ◽  
...  
Keyword(s):  
Chicken Thymus

scholarly journals Thymic transcriptome analysis after Newcastle disease virus inoculation in chickens and the influence of host small RNAs on NDV replication

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Liangxing Guo ◽  
Zhaokun Mu ◽  
Furong Nie ◽  
Xuanniu Chang ◽  
Haitao Duan ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Viral Disease ◽  
Immune Genes ◽  
Comprehensive Information ◽  
Virulent Newcastle Disease Virus ◽  
Chicken Thymus ◽  
Innate Immune Genes

AbstractNewcastle disease (ND), caused by virulent Newcastle disease virus (NDV), is a contagious viral disease affecting various birds and poultry worldwide. In this project, differentially expressed (DE) circRNAs, miRNAs and mRNAs were identified by high-throughput RNA sequencing (RNA-Seq) in chicken thymus at 24, 48, 72 or 96 h post LaSota NDV vaccine injection versus pre-inoculation group. The vital terms or pathways enriched by vaccine-influenced genes were tested through KEGG and GO analysis. DE genes implicated in innate immunity were preliminarily screened out through GO, InnateDB and Reactome Pathway databases. The interaction networks of DE innate immune genes were established by STRING website. Considering the high expression of gga-miR-6631-5p across all the four time points, DE circRNAs or mRNAs with the possibility to bind to gga-miR-6631-5p were screened out. Among DE genes that had the probability to interact with gga-miR-6631-5p, 7 genes were found to be related to innate immunity. Furthermore, gga-miR-6631-5p promoted LaSota NDV replication by targeting insulin induced gene 1 (INSIG1) in DF-1 chicken fibroblast cells. Taken together, our data provided the comprehensive information about molecular responses to NDV LaSota vaccine in Chinese Partridge Shank Chickens and elucidated the vital roles of gga-miR-6631-5p/INSIG1 axis in LaSota NDV replication.

Immunoreactive neurotensin and somatostatin in the chicken thymus

1978 ◽  
Vol 194 (3) ◽  
Author(s):  
Frank Sundler ◽  
R.E. Carraway ◽  
R. H�kanson ◽  
J. Alumets ◽  
M.P. Dubois
Keyword(s):  
Chicken Thymus

Immunohistochemical assessment of the neurosecretory cells of the chicken thymus using a novel monoclonal antibody against avian chromogranin A

2004 ◽  
Vol 28 (4) ◽  
pp. 337-345 ◽  
Author(s):  
Cherie M Oubre ◽  
Xiaodong Zhang ◽  
Kathleen E Clements ◽  
Tom E Porter ◽  
Luc R Berghman
Keyword(s):  
Monoclonal Antibody ◽  
Chromogranin A ◽  
Neurosecretory Cells ◽  
Immunohistochemical Assessment ◽  
Chicken Thymus

scholarly journals DEVELOPMENT OF THE EMBRYONIC CHICKEN THYMUS III. UNEQUAL DIVISION OF LYMPHOID CELLS

1979 ◽  
Vol 21 (3) ◽  
pp. 189-194 ◽  
Author(s):  
MASANOBU SUGIMOTO ◽  
TOMOYOSHI YASUDA ◽  
YASUYUKI EGASHIRA
Keyword(s):  
Lymphoid Cells ◽  
Unequal Division ◽  
Embryonic Chicken ◽  
Chicken Thymus

scholarly journals IMMUNOCOMPETENT CELLS OF THE CHICKEN

1971 ◽  
Vol 134 (4) ◽  
pp. 1036-1045 ◽  
Author(s):  
W. P. McArthur ◽  
J. Chapman ◽  
G. J. Thorbecke
Keyword(s):  
Guinea Pig ◽  
Surface Antigen ◽  
T Lymphocyte ◽  
The Other ◽  
Bursa Of Fabricius ◽  
Spleen Cells ◽  
Lymphocyte Antigen ◽  
Specific Antisera ◽  
Chicken Thymus ◽  
Thymus Cells

Specific antisera to chicken thymus and to bursa of Fabricius were obtained in rabbits. After appropriate absorption and dilution all four anti-thymus sera, in the presence of guinea pig C', killed >90% of thymus and ≦12% of bursa cells. They were cytotoxic for approximately 50% of spleen cells and did not affect antibody-forming cells. The surface antigen detected by these antisera was named chicken T-lymphocyte antigen (CTLA). Two of four anti-bursa sera, under similar conditions, killed >90% of bursa cells and ≦10% of thymus cells. These antisera were cytotoxc for a large percentage of antibody-forming cells and killed approximately 30% of spleen cells The other two anti-bursa sera were somewhat less potent but showed similar specificity. The surface antigen detected by these antisera was named chicken bursa-derived lymphocyte antigen (CBuLA). Rabbit antisera to chicken immunoglobulin were cytotoxic for bursa but not for thymus cells and killed a similar percentage of spleen cells as did anti-bursa sera. They were also cytotoxic for antibody-forming cells.

Mitogen-Reactive Lymphocytes in the Embryonic Chicken Thymus in Organ Culture

1974 ◽  
Vol 47 (3) ◽  
pp. 388-399 ◽  
Author(s):  
Jan F. Sällström ◽  
Gunnar V. Alm
Keyword(s):  
Organ Culture ◽  
Embryonic Chicken ◽  
Chicken Thymus ◽  
Reactive Lymphocytes

ANALYSIS OF TIME DEPENDENT CHANGES OF LYMPHOPOIETIC ACTIVITY IN ORGAN CULTURES OF EMBRYONIC CHICKEN THYMUS

1975 ◽  
Vol 8 (6) ◽  
pp. 569-577
Author(s):  
Roger JUhlin ◽  
Gunnar V. Alm
Keyword(s):  
Time Dependent ◽  
Organ Cultures ◽  
Embryonic Chicken ◽  
Chicken Thymus
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