A Modified Synthesis of Some Novel Polycyclic Aromatic Phenazines and Quinoxalines by Using the Tungstate Sulfuric Acid (TSA) as a Reusable Catalyst under Solvent-free Conditions

2012 ◽  
Vol 59 (2) ◽  
pp. 187-192 ◽  
Author(s):  
Bahador Karami ◽  
Saeed Khodabakhshi ◽  
Marzieh Nikrooz
Keyword(s):  
Sulfuric Acid ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Solvent Free Conditions ◽  
Polycyclic Aromatic

Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones over Silica Sulfuric Acid as a Reusable Catalyst under Solvent-Free Conditions.

ChemInform ◽  
2004 ◽  
Vol 35 (7) ◽  
Author(s):  
Peyman Salehi ◽  
Minoo Dabiri ◽  
Mohammad Ali Zolfigol ◽  
Mohammad Ali Bodaghi Fard
Keyword(s):  
Sulfuric Acid ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Efficient Synthesis ◽  
Silica Sulfuric Acid ◽  
Solvent Free Conditions

Facile and green synthesis of triarylmethanes using silica sulfuric acid as a reusable catalyst under solvent-free conditions

2011 ◽  
Vol 14 (10) ◽  
pp. 934-943 ◽  
Author(s):  
I. Mohammadpoor-Baltork ◽  
M. Moghadam ◽  
S. Tangestaninejad ◽  
V. Mirkhani ◽  
K. Mohammadiannejad-Abbasabadi ◽  
...  
Keyword(s):  
Sulfuric Acid ◽  
Green Synthesis ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Silica Sulfuric Acid ◽  
Solvent Free Conditions

scholarly journals A Green Synthesis of 1,5-Benzodiazepines using Reusable-Heterogeneous Silica Sulfuric Acid Catalyst under Solvent-Free Conditions and their Antileukemic Activity

2021 ◽  
Vol 33 (5) ◽  
pp. 1006-1012
Author(s):  
Kachigere B. Harsha ◽  
Chandagirikoppal V. Kavitha ◽  
Toreshettahally R. Swaroop ◽  
Shobith Rangappa ◽  
Kanchugarakoppal S. Rangappa
Keyword(s):  
Sulfuric Acid ◽  
Cell Lines ◽  
Acid Catalyst ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
G1 Arrest ◽  
Silica Sulfuric Acid ◽  
Hydrogen Atoms ◽  
Solvent Free Conditions ◽  
Sulfuric Acid Catalyst

1,5-Benzodiazepine derivatives are readily assembled from o-phenylene diamine and ketones containg α-hydrogen atoms by means of simple cyclocondensation via sp3 C-H activation promoted by an efficient heterogeneous silica sulfuric acid catalyst. Eco-friendliness, good yields, easy workup, reusable catalyst, short reaction times, high atom economy and solvent-free conditions are the noteworthy features of this protocol. These benzodiazepines are chosen for the evaluation of antiproliferative activity against different leukemia cell lines. Among the investigated compounds, 3g is the best antiproliferative agent against all the cell lines tested. Also, current preliminary analysis showed that compound 3g phosphorylates ERK1/2 and induces G1 arrest in K562 cells

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