scholarly journals Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering

2010 ◽  
Vol 222 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Stephen M. Richardson ◽  
Judith A. Hoyland ◽  
Reza Mobasheri ◽  
Constanze Csaki ◽  
Mehdi Shakibaei ◽  
...  
Methods ◽  
2016 ◽  
Vol 99 ◽  
pp. 69-80 ◽  
Author(s):  
Stephen M. Richardson ◽  
Gauthaman Kalamegam ◽  
Peter N. Pushparaj ◽  
Csaba Matta ◽  
Adnan Memic ◽  
...  

2018 ◽  
Vol 18 (3) ◽  
pp. 264 ◽  
Author(s):  
Roberto Berebichez-Fridman ◽  
Pablo R. Montero-Olvera

First discovered by Friedenstein in 1976, mesenchymal stem cells (MSCs) are adult stem cells found throughout the body that share a fixed set of characteristics. Discovered initially in the bone marrow, this cell source is considered the gold standard for clinical research, although various other sources—including adipose tissue, dental pulp, mobilised peripheral blood and birth-derived tissues—have since been identified. Although similar, MSCs derived from different sources possess distinct characteristics, advantages and disadvantages, including their differentiation potential and proliferation capacity, which influence their applicability. Hence, they may be used for specific clinical applications in the fields of regenerative medicine and tissue engineering. This review article summarises current knowledge regarding the various sources, characteristics and therapeutic applications of MSCs.Keywords: Mesenchymal Stem Cells; Adult Stem Cells; Regenerative Medicine; Cell Differentiation; Tissue Engineering.


2018 ◽  
Vol 46 (sup2) ◽  
pp. 431-440 ◽  
Author(s):  
Behrouz Farhadihosseinabadi ◽  
Mehrdad Farahani ◽  
Tahereh Tayebi ◽  
Ameneh Jafari ◽  
Felor Biniazan ◽  
...  

JOR Spine ◽  
2019 ◽  
Vol 2 (1) ◽  
pp. e1043 ◽  
Author(s):  
Markus Loibl ◽  
Karin Wuertz‐Kozak ◽  
Gianluca Vadala ◽  
Siegmund Lang ◽  
Jeremy Fairbank ◽  
...  

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