Lipofectamine 2000/siRNA complexes cause endoplasmic reticulum unfolded protein response in human endothelial cells

2019 ◽  
Vol 234 (11) ◽  
pp. 21166-21181
Author(s):  
Zhengzheng Li ◽  
Chi Zhang ◽  
Zhiting Wang ◽  
Jian Shen ◽  
Pingping Xiang ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Endoplasmic Reticulum ◽  
Unfolded Protein Response ◽  
Human Endothelial Cells ◽  
Unfolded Protein ◽  
Protein Response ◽  
Lipofectamine 2000

Endoplasmic reticulum Metallo protease 1, a triggering factor for unfolded protein response and promising target in colorectal cancer

Biologia ◽  
2021 ◽  
Author(s):  
Sanaz Dastghaib ◽  
Pooneh Mokarram ◽  
Mehran Erfani ◽  
Saeid Ghavami ◽  
Seyed Vahid Hosseini ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Endoplasmic Reticulum ◽  
Unfolded Protein Response ◽  
Unfolded Protein ◽  
Promising Target ◽  
Triggering Factor ◽  
Protein Response

Aberrant Accumulation of Fibulin-3 in the Endoplasmic Reticulum Leads to Activation of the Unfolded Protein Response and VEGF Expression

2005 ◽  
Vol 46 (11) ◽  
pp. 3973 ◽  
Author(s):  
C. Nathaniel Roybal ◽  
Lihua Y. Marmorstein ◽  
David L. Vander Jagt ◽  
Steve F. Abcouwer
Keyword(s):  
Endoplasmic Reticulum ◽  
Unfolded Protein Response ◽  
Vegf Expression ◽  
Unfolded Protein ◽  
The Unfolded Protein Response ◽  
Protein Response

scholarly journals The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane.

1997 ◽  
Vol 8 (9) ◽  
pp. 1805-1814 ◽  
Author(s):  
J S Cox ◽  
R E Chapman ◽  
P Walter
Keyword(s):  
Endoplasmic Reticulum ◽  
Unfolded Protein Response ◽  
Secretory Pathway ◽  
Lipid Synthesis ◽  
Secretory Proteins ◽  
Endoplasmic Reticulum Membrane ◽  
Yeast Saccharomyces Cerevisiae ◽  
Unfolded Protein ◽  
The Unfolded Protein Response ◽  
Protein Response

The endoplasmic reticulum (ER) is a multifunctional organelle responsible for production of both lumenal and membrane components of secretory pathway compartments. Secretory proteins are folded, processed, and sorted in the ER lumen and lipid synthesis occurs on the ER membrane itself. In the yeast Saccharomyces cerevisiae, synthesis of ER components is highly regulated: the ER-resident proteins by the unfolded protein response and membrane lipid synthesis by the inositol response. We demonstrate that these two responses are intimately linked, forming different branches of the same pathway. Furthermore, we present evidence indicating that this coordinate regulation plays a role in ER biogenesis.

scholarly journals Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response

2012 ◽  
Vol 26 (6) ◽  
pp. 2437-2445 ◽  
Author(s):  
Soumen Kahali ◽  
Bhaswati Sarcar ◽  
Antony Prabhu ◽  
Edward Seto ◽  
Prakash Chinnaiyan
Keyword(s):  
Endoplasmic Reticulum ◽  
Unfolded Protein Response ◽  
Histone Deacetylases ◽  
Class I ◽  
Unfolded Protein ◽  
The Unfolded Protein Response ◽  
Protein Response

scholarly journals Cadmium impairs protein folding in the endoplasmic reticulum and induces the unfolded protein response

2016 ◽  
Vol 16 (5) ◽  
pp. fow049 ◽  
Author(s):  
Quynh Giang Le ◽  
Yuki Ishiwata-Kimata ◽  
Kenji Kohno ◽  
Yukio Kimata
Keyword(s):  
Endoplasmic Reticulum ◽  
Protein Folding ◽  
Unfolded Protein Response ◽  
Unfolded Protein ◽  
The Unfolded Protein Response ◽  
Protein Response
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