Biodesulfurization of dibenzothiophene by resting cells ofPseudomonas putidaCECT5279: influence of the oxygen transfer rate in the scale-up from shaken flask to stirred tank reactor

2014 ◽  
Vol 91 (1) ◽  
pp. 184-189 ◽  
Author(s):  
Igor Martinez ◽  
Victoria E Santos ◽  
Emilio Gomez ◽  
Felix Garcia-Ochoa
Keyword(s):  
Oxygen Transfer ◽  
Transfer Rate ◽  
Scale Up ◽  
Oxygen Transfer Rate ◽  
Stirred Tank ◽  
Resting Cells ◽  
Stirred Tank Reactor ◽  
Tank Reactor

scholarly journals Circulating Jet for Enhancing the Mass Transfer in a Gas-liquid Stirred Tank Reactor

2021 ◽  
Author(s):  
Lei Wang ◽  
Xiao Xu ◽  
Hualin Wang ◽  
HongLai Liu ◽  
Qiang Yang
Keyword(s):  
Mass Transfer ◽  
Scale Up ◽  
Input Power ◽  
Stirred Tank ◽  
Exhaust Gas ◽  
Stirred Tank Reactor ◽  
Tank Reactor ◽  
Mass Transfer Efficiency ◽  
Low Mass ◽  
Liquid Mass Transfer

A gas-liquid stirred tank reactor (STR) has some problems, such as low mass transfer efficiency, high exhaust gas oxygen concentration, and low product conversion rate, due to limitations of stirring speed and input power. This article proposes a method to enhance the gas-liquid mass transfer in a STR using circulating jet internals. When a circulating jet is added, the average bubble size in the reactor is reduced to 1.26 mm, and the overall gas holdup is increased to 8.23%, which is an increase of 3.62 times of the original STR. The gas-liquid volumetric mass transfer coefficient is increased to 0.05556 s-1, which is 4.84 times of the original STR. The unit volume power is increased by only 1.4 times. These data provide references for the design and scale-up of new jet STRs.

scholarly journals Scale-up synthesis of lipase-catalyzed palm esters in stirred-tank reactor

2008 ◽  
Vol 99 (14) ◽  
pp. 6097-6104 ◽  
Author(s):  
P KENG ◽  
M BASRI ◽  
A ARIFF ◽  
M ABDULRAHMAN ◽  
R ABDULRAHMAN ◽  
...  
Keyword(s):  
Scale Up ◽  
Stirred Tank ◽  
Stirred Tank Reactor ◽  
Tank Reactor

Characterization and Scale-Up of Cyanogen Bromide Chemical Activation of Sepharose CL-4B in a Stirred Tank Reactor to Purify the rHBsAg

2008 ◽  
Vol 6 (1) ◽  
Author(s):  
Eutimio G Fernández ◽  
José A. Montero ◽  
Rodolfo Valdés ◽  
Milagros G Arce ◽  
Andrés B Tamayo ◽  
...  
Keyword(s):  
Hepatitis B Surface Antigen ◽  
Chemical Activation ◽  
Scale Up ◽  
Stirred Tank ◽  
Stirred Tank Reactor ◽  
Tank Reactor ◽  
Matrix Quality ◽  
Activation Procedure ◽  
The Matrix ◽  
Volume Unit

The aim of this paper was to characterize and to scale-up the CNBr chemical activation of Sepharose CL-4B in a stirred tank reactor to purify the recombinant Hepatitis B surface antigen for use in vaccines. The activation quality was assessed measuring the concentration of the cyanate esters and the percentage of nitrogen in the activated matrix. The Sepharose CL-4B incorporated less than 50% of the initial CNBr amount added to the matrix, but the monoclonal antibody CB.Hep-1, used as immunoligand to purify the rHBsAg, was efficiently immobilized in a weakly activated matrix (<8 ?mol/mL of matrix). The impellent type has a significant influence on activated matrix quality. The constant power per volume unit was a proper criterion to scale-up the Sepharose CL-4B March's modified chemical activation procedure with CNBr.

scholarly journals Study on Mixing in Scale-up of Stirred Tank Reactor for Continuous Bulk Polymerization.

1996 ◽  
Vol 22 (2) ◽  
pp. 264-269 ◽  
Author(s):  
Yoshio Fuchigami ◽  
Masaya Nagai ◽  
Tsuyoshi Sugiyama
Keyword(s):  
Scale Up ◽  
Bulk Polymerization ◽  
Stirred Tank ◽  
Stirred Tank Reactor ◽  
Tank Reactor

scholarly journals Study on Heat Transfer in Scale-up of Stirred Tank Reactor Using Maxblend Impeller for Continuous Bulk Polymerization.

1996 ◽  
Vol 22 (3) ◽  
pp. 480-487
Author(s):  
Yoshio Fuchigami ◽  
Toshiaki Inami ◽  
Yosokichi Kobayashi ◽  
Akira Hashimoto
Keyword(s):  
Heat Transfer ◽  
Scale Up ◽  
Bulk Polymerization ◽  
Stirred Tank ◽  
Stirred Tank Reactor ◽  
Tank Reactor
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