scholarly journals Systematic review with meta‐analysis: Safety and efficacy of local injections of mesenchymal stem cells in perianal fistulas

JGH Open ◽  
2019 ◽  
Vol 3 (3) ◽  
pp. 249-260 ◽  
Author(s):  
Rachele Ciccocioppo ◽  
Catherine Klersy ◽  
Daniel A Leffler ◽  
Raquel Rogers ◽  
Dimitri Bennett ◽  
...  
Keyword(s):  
Systematic Review ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Meta Analysis ◽  
Safety And Efficacy ◽  
Perianal Fistulas ◽  
Local Injections

scholarly journals Clinical Efficacy of Mesenchymal Stem Cells in Bone Regeneration in Oral Implantology. Systematic Review and Meta-Analysis

2021 ◽  
Vol 18 (3) ◽  
pp. 894
Author(s):  
Sonia Egido-Moreno ◽  
Joan Valls-Roca-Umbert ◽  
Juan Manuel Céspedes-Sánchez ◽  
José López-López ◽  
Eugenio Velasco-Ortega
Keyword(s):  
Systematic Review ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Bone Regeneration ◽  
Meta Analysis ◽  
Cell Group ◽  
Control Group ◽  
Publication Date ◽  
Native Bone

In bone regeneration, obtaining a vital bone as similar as possible to native bone is sought. This review aimed to evaluate the efficacy of stem cells in maxillary bone regeneration for implant rehabilitation and to review the different techniques for obtaining and processing these cells. A systematic review and meta-analysis were performed using the Pubmed/Medline (NCBI), Cochrane, Scielo, and Scopus databases, without restriction on the publication date. The following Mesh terms were used, combined by the Boolean operator “AND”: “dental implants” AND “stem cells” AND “bioengineering”. Applying inclusion and exclusion criteria, five articles were obtained and three were added after manual search. The results from the meta-analysis (18 patients) did not provide significant differences despite the percentage of bone formed in the maxillary sinus, favoring the stem cell group, and the analysis of the percentage of residual Bio-Oss® showed results favoring the control group. Stem cell regeneration usually shows positive vascular and viable bone formation. In conclusion, using mesenchymal stem cells in bone regeneration provides benefits in the quality of bone, similar or even superior to autologous bone, all this through a minimally invasive procedure.

scholarly journals A Systematic Review of the Safety and Efficacy of Mesenchymal Stem Cells for Disc Degeneration: Insights and Future Directions for Regenerative Therapeutics

2014 ◽  
Vol 23 (21) ◽  
pp. 2553-2567 ◽  
Author(s):  
Rita Lok-Hay Yim ◽  
Juliana Tsz-Yan Lee ◽  
Cora H. Bow ◽  
Björn Meij ◽  
Victor Leung ◽  
...  
Keyword(s):  
Systematic Review ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Disc Degeneration ◽  
Future Directions ◽  
Safety And Efficacy
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