Catalyst-free, Knoevenagel-Michael Addition Reaction of Dimedone under Microwave Irradiation: An Efficient One-pot Synthesis of Polyhydroquinoline Derivatives

2013 ◽  
Vol 50 (4) ◽  
pp. 941-944 ◽  
Author(s):  
M. Saha ◽  
T. S. Luireingam ◽  
T. Merry ◽  
A. K. Pal
Keyword(s):  
Microwave Irradiation ◽  
Michael Addition ◽  
Addition Reaction ◽  
Michael Addition Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis

Pyridine-grafted graphene oxide: a reusable acid–base bifunctional catalyst for the one-pot synthesis of β-phosphonomalonates via a cascade Knoevenagel–phospha Michael addition reaction in water

RSC Advances ◽  
2015 ◽  
Vol 5 (117) ◽  
pp. 96532-96538 ◽  
Author(s):  
Sara Sobhani ◽  
Farzaneh Zarifi
Keyword(s):  
Graphene Oxide ◽  
Michael Addition ◽  
Addition Reaction ◽  
Bifunctional Catalyst ◽  
Michael Addition Reaction ◽  
Acid Base ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One ◽  
Reaction In Water

Py–GO as a new acid–base bifunctional catalyst was synthesized and employed for the one-pot synthesis of β-phosphonomalonates in water.

Catalyst-Free One-Pot Synthesis of Chromeno-Imidazo-Pyridinones by an Aza-Michael Addition/Rearrangement/Heterocyclization Tandem Reaction

Synlett ◽  
2018 ◽  
Vol 29 (11) ◽  
pp. 1437-1440 ◽  
Author(s):  
Oualid Talhi ◽  
Norah Bennamane ◽  
Artur Silva ◽  
Houria Lakhdari ◽  
Ridha Hassaine ◽  
...  
Keyword(s):  
Michael Addition ◽  
Room Temperature ◽  
Addition Reaction ◽  
2D Nmr ◽  
X Ray Diffraction ◽  
One Pot ◽  
X Ray ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
New Compounds

A one-pot synthesis of a novel series of chromeno-imidazo-pyridinone derivatives from 3-[(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl]chromones and ethane-1,2-diamine at room temperature under catalyst-free conditions has been successfully developed. This approach involves a tandem aza-Michael addition reaction, a chromone-to-chromanone rearrangement, and a heterocyclization sequence, leading to chromeno-imidazo-pyridinone polyheterocycles. The structure and absolute configurations of the new compounds were elucidated by a combination of 1D- and 2D-NMR analyses and single-crystal X-ray diffraction.

Facile one-pot synthesis of novel water-soluble fluorescent hyperbranched poly(amino esters)

RSC Advances ◽  
2016 ◽  
Vol 6 (91) ◽  
pp. 88030-88037 ◽  
Author(s):  
Yuqun Du ◽  
Hongxia Yan ◽  
Song Niu ◽  
Lihua Bai ◽  
Fu Chai
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Water Soluble ◽  
Michael Addition Reaction ◽  
One Pot ◽  
Amino Esters ◽  
One Pot Synthesis ◽  
Hyperbranched Poly ◽  
Trimethylolpropane Triacrylate ◽  
Aliphatic Diamines

Two kinds of water-soluble fluorescent hyperbranched poly(amino esters) were first synthesized by a convenient one-pot approach via the A2 + B3 Michael addition reaction of trimethylolpropane triacrylate and aliphatic diamines.

Catalyst-Free One-Pot Synthesis of Novel Heteroarylamine Substituted Furo[3,2-c]coumarins

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Mahnaz Saraei ◽  
Reyhaneh Khoeiniha
Keyword(s):  
Michael Addition ◽  
Aldol Condensation ◽  
Ring Closure ◽  
Dehydration Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Tandem Process ◽  
First Time

A high-yielding cyclocondensation of 4-hydroxycoumarin, phenylglyoxal monohydrate, and heteroarylamines proceeds without catalysis, which gives novel functionalized furo[3,2-c]coumarins and heteroarylamino alkylation of coumarin products in acetonitrile under reflux, is reported for the first time. This tandem process involves sequentially an aldol condensation, Michael addition, a ring closure, and dehydration reaction.

Efficient Synthesis of 3-Amino-1,5-benzodiazepine-2-one Derivatives

Synlett ◽  
2017 ◽  
Vol 28 (10) ◽  
pp. 1183-1186 ◽  
Author(s):  
Nobuhiro Obara ◽  
Takeshi Watanabe ◽  
Tomohiro Asakawa ◽  
Toshiyuki Kan ◽  
Takao Tanaka
Keyword(s):  
Michael Addition ◽  
Convenient Method ◽  
Addition Reaction ◽  
Efficient Synthesis ◽  
Michael Addition Reaction ◽  
One Pot ◽  
Simple Method ◽  
The Michael Addition

A convenient method for synthesizing 3-amino-1,5-benzodiazepine-2-one via the Michael addition reaction of o-phenylenediamine with dehydroalanine ester derivatives, followed by cyclization, was developed. This simple method was used to obtain a variety of N-substituted 3-amino-1,5-benzodiazepine-2-ones in one pot with good yields.

Access to 3-Arylindoles through a Tandem One-Pot Protocol Involving Dearomatization, a Regioselective Michael Addition Reaction, and Rearomatization

2014 ◽  
Vol 2014 (12) ◽  
pp. 2565-2575 ◽  
Author(s):  
Santhosh Kumar Chittimalla ◽  
Chennakesavulu Bandi ◽  
Sireesha Putturu ◽  
Rajesh Kuppusamy ◽  
Kevin Christopher Boellaard ◽  
...  
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Michael Addition Reaction ◽  
One Pot
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