Autocorrelated13c-13c double quantum coherence two-dimensional nmr spectroscopy: Utilization of a modified version of the technique as an adjunct in the total assignment of the1h- and13c-nmr spectra of the mutagen phenanthro[3,4-b]thiophene

1983 ◽  
Vol 20 (6) ◽  
pp. 1661-1669 ◽  
Author(s):  
M. J. Musmar ◽  
M. Robert Willcott ◽  
Gary E. Martin ◽  
Robert T. Gampe ◽  
Masatomo Iwao ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Quantum Coherence ◽  
Nmr Spectra ◽  
Double Quantum ◽  
Two Dimensional

Structural studies of digitoxin and related cardenolides by two-dimensional NMR

1990 ◽  
Vol 68 (2) ◽  
pp. 272-277 ◽  
Author(s):  
Torbjörn Drakenberg ◽  
Peter Brodelius ◽  
Deane D. McIntyre ◽  
Hans J Vogel
Keyword(s):  
Nmr Spectroscopy ◽  
Nmr Spectra ◽  
Chair Conformation ◽  
Coupling Constants ◽  
Two Dimensional ◽  
Structural Studies ◽  
Solution Conformation ◽  
Phase Sensitive ◽  
Multiple Relay ◽  
C Nmr

The 1H and 13C NMR spectra of the cardenolides digitoxigenin, digoxigenin, digitoxin, and mono- and bis-digitoxigenin digitoxosides have been completely assigned by two-dimensional NMR spectroscopy. The techniques used include phase-sensitive COSY, multiple relay COSY, and carbon–proton correlation (HETCOR and HMQC) spectra. Various aspects of the solution conformation of the steroid moiety of digitoxin and digoxigenin could be determined from coupling constants and NOE difference experiments and they are indicative of an all-chair conformation. The carbohydrate rings in digitoxin and the mono- and bis-digitoxigenin digitoxosides are also in the chair conformation. Keywords: cardenolides, digitoxigenin, digitoxin, 2-dimensional NMR, conformational analysis.

Narcissus Alkaloids, XIII. Complete Assignment of the Nmr Spectra of Papyramine and 6-epi-Papyramine by Two-Dimensional Nmr Spectroscopy

1990 ◽  
Vol 53 (6) ◽  
pp. 1456-1462 ◽  
Author(s):  
Jaume Bastida ◽  
Carles Codina ◽  
Francesc Viladomat ◽  
Mario Rubiralta ◽  
Jean-Charles Quirion ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Nmr Spectra ◽  
Two Dimensional ◽  
Complete Assignment
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