GC-MS separation and quantitation of 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid and hippuric acid from plasma of patients with renal failure: Application to blood purification methods

1992 ◽  
Vol 15 (9) ◽  
pp. 601-604 ◽  
Author(s):  
Hartmut M. Liebich ◽  
Anna-Maria Reichenmiller ◽  
Hans-Günther Wahl ◽  
Birgid Tetschner ◽  
Teut Risler ◽  
...  
Keyword(s):  
Renal Failure ◽  
Hippuric Acid ◽  
Blood Purification ◽  
Purification Methods

Overview of blood purification in uremia

1980 ◽  
Vol 3 (4) ◽  
pp. 203-208
Author(s):  
B.T. Burton
Keyword(s):  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Renal Transplantation ◽  
Rejection Rate ◽  
Blood Purification ◽  
Maintenance Hemodialysis ◽  
Dialysis Patients ◽  
Transplant Patients ◽  
Maintenance Dialysis ◽  
Transplanted Kidneys

Today, management of irreversible renal failure is based primarily on maintenance hemodialysis and renal transplantation with a growing minority of patients treated by peritoneal dialysis. With regard to renal transplantation — the early promise of renal transplantation in the mid 1960's has given way to the realities of the late 1970's. There have been no major changes in the rejection rate of transplanted kidneys in recent years though today's mortality of transplant patients is considerably reduced over what it used to be. Moreover, universally the lack of availability of a sufficient number of organs for transplantation poses a formidable problem. It is all too apparent that current methods of blood purification in uremia are far from optimal. Even though the mortality in maintenance dialysis is relatively low, hemodialysis is characterized by a variety of complications and most maintenance dialysis patients are not optimally rehabilitated.

scholarly journals Combined use of different blood purification methods to treat severe acute pancreatitis: an analysis of 32 cases

2009 ◽  
Vol 17 (26) ◽  
pp. 2752
Author(s):  
Xiang-Yang Huang ◽  
Min Zhang ◽  
Xue-Xia Song ◽  
Ying Wang ◽  
Chun-E Luo ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Blood Purification ◽  
Combined Use ◽  
Purification Methods

Effect of Preparation of β2M Nano Antibody Adsorbent for Blood Purification on Dialysis Complications in Patients with Renal Failure

2021 ◽  
Vol 13 (1) ◽  
pp. 161-170
Author(s):  
Jianyun Peng ◽  
Yongling Tao ◽  
Xiaoru Zhang ◽  
Meijuan Xiang ◽  
Zhihong Gui ◽  
...  
Keyword(s):  
Renal Failure ◽  
Adsorption Capacity ◽  
Phage Display Library ◽  
Blood Purification ◽  
Dynamic Adsorption ◽  
Plasma System ◽  
Ligand Density ◽  
E Coli ◽  
Dialysis Complications ◽  
Library Technology

In order to purify blood and adsorb β2M, a highly selective immunosorbent biomaterial based on nano antibody was designed. First of all, nanoantibodies against β2M in patients with renal failure are screened by phage display library technology. After 4 rounds of screening, 12 kinds of monoclonal phage samples are compared by ELISA, and the highest affinity sequence A53 is obtained. Then, the nano antibody A53 is transferred into two kinds of host bacteria respectively, and the host E. coli Shuffle T7 is selected, and then purified by nickel column affinity, thus obtaining high purity nano antibody A53S. Five kinds of nano antibody adsorbents are prepared by using A53S as a component of adsorbent. The results show that the effect of D series adsorbent with ɛ-poly-L-lysine as spacer is better, but the ligand density should be adjusted reasonably to ensure the activity of nanoantibody protein. When the loading concentration of β2M is set to 1.8 mg/ml, adsorbent D-1 can adsorb 11.78 mg/ml of dynamic adsorption capacity of β2M. This index is significantly higher than the dynamic adsorption capacity of plasma system under the same conditions (P < 0.05), which proves that the nano antibody adsorbent biomaterial can effectively adsorb β2M, thus reducing the probability of dialysis complications.

The Occurrence of Fever during Hemodialysis and Hemofiltration. A Comparative Study

1986 ◽  
Vol 9 (4) ◽  
pp. 247-250 ◽  
Author(s):  
K. Schaefer ◽  
D. von Herrath ◽  
M. Hüfler ◽  
A. Pauls
Keyword(s):  
Retrospective Study ◽  
Antibiotic Therapy ◽  
Comparative Study ◽  
Interleukin 1 ◽  
Blood Purification ◽  
Clear Explanation ◽  
Purification Methods ◽  
Febrile Episodes ◽  
Conventional Hemodialysis

The occurence of fever during various blood purification methods was evaluated in a retrospective study. It could be demonstrated, that patients treated chronically by conventional hemodialysis experience six times more febrile episodes than patients on chronic hemofiltration (4.84% versus 0.81%). Since many of the increased temperatures could not be explained by conventional means, it has to be assumed that the treatment itself caused the fever, possibly activating the monocyte hormone interleukin 1. It is of further note that there was no difference in the mangnitude of the temperature due to septicaemia or to no obvious cause. This finding necessitates in our opinion an early antibiotic therapy in those cases where fever develops without clear explanation.

Organic Acids And Other Metabolites In Renal Failure And Their Removal With Blood Purification Procedures

1984 ◽  
pp. 38-44
Author(s):  
K. Maeda ◽  
T. Shinzato ◽  
T. Niwa ◽  
M. Usuda ◽  
R. Sezaki ◽  
...  
Keyword(s):  
Renal Failure ◽  
Organic Acids ◽  
Blood Purification

HEMODYNAMIC PARAMETERS DURING BLOOD PURIFICATION IN PATIENTS WITH ACUTE RENAL FAILURE AFTER SURGERY

Shock ◽  
1995 ◽  
Vol 4 (Supplement) ◽  
pp. 45
Author(s):  
Yukio Endoh ◽  
Ryoichi Motoki ◽  
Hitosi Inoue ◽  
Akira Usuba ◽  
Junichi Miura ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Blood Purification ◽  
Hemodynamic Parameters
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