Influence of Extracellular Calcium on the Metabolism of Arachidonic Acid in Alveolar Macrophages

1990 ◽  
Vol 48 (6) ◽  
pp. 502-511 ◽  
Author(s):  
Stephen M. Taylor ◽  
William W. Laegreid ◽  
Mark D. Englen ◽  
Ginger M. Dani ◽  
Ron M. Silflow ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Alveolar Macrophages ◽  
Extracellular Calcium

Metabolism of arachidonic acid in rabbit alveolar macrophages

Inflammation ◽  
1977 ◽  
Vol 2 (3) ◽  
pp. 191-197 ◽  
Author(s):  
Saura Sahu ◽  
William S. Lynn
Keyword(s):  
Arachidonic Acid ◽  
Alveolar Macrophages

Effect of extracellular calcium on superoxide release by rat alveolar macrophages

1983 ◽  
Vol 54 (5) ◽  
pp. 1249-1253 ◽  
Author(s):  
H. J. Forman ◽  
J. Nelson
Keyword(s):  
Concanavalin A ◽  
Alveolar Macrophages ◽  
Extracellular Calcium ◽  
Extracellular Medium ◽  
Absolute Requirement ◽  
Superoxide Release

Alveolar macrophages can be stimulated to release superoxide into the extracellular medium. The mechanism of activation of superoxide release has been reported to be mediated by the movement of Ca2+ into the cytosol, but the involvement of extracellular Ca2+ in this process has remained uncertain. Extracellular Ca2+ was not an absolute requirement for activation of superoxide release; however, 1.3 mM extracellular Ca2+ caused an approximate twofold enhancement of superoxide release stimulated by either concanavalin A or formyl-methionyl-leucyl-phenylalanine but had no effect on digitonin-stimulated superoxide release. Concanavalin A-stimulated superoxide was inhibited by the “Ca2+ entry blockers,” Mn2+ (1 microM) or methoxyverapamil (D-600) (100 microM). Inhibition by Mn2+ was competitive with extracellular Ca2+, whereas inhibition by D-600 was noncompetitive. Neither inhibitor, however, affected superoxide release after initiation. Thus activation of superoxide release by alveolar macrophages can be accomplished, in part, through the entrance of Ca2+ into the cell.

Lyso(bis)phosphatidic acid: A novel source of arachidonic acid for oxidative metabolism by rabbit alveolar macrophages

1985 ◽  
Vol 130 (2) ◽  
pp. 800-806 ◽  
Author(s):  
Felicia R. Cochran ◽  
Janice R. Connor ◽  
Vicki L. Roddick ◽  
B.Moseley Waite
Keyword(s):  
Arachidonic Acid ◽  
Phosphatidic Acid ◽  
Alveolar Macrophages ◽  
Oxidative Metabolism

Down-regulation of Arachidonic Acid Metabolism By Sarcoid Alveolar Macrophages

CHEST Journal ◽  
1986 ◽  
Vol 89 (3) ◽  
pp. 182S-185S ◽  
Author(s):  
Peter R. Bachwich ◽  
Joseph P. Lynch ◽  
Lori A. Quinlan ◽  
Steven L. Kunkel
Keyword(s):  
Arachidonic Acid ◽  
Alveolar Macrophages ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Down Regulation

Inhibition of the liberation of arachidonic acid by cadmium ions in rabbit alveolar macrophages

1992 ◽  
Vol 66 (2) ◽  
pp. 131-136 ◽  
Author(s):  
Naomi Kudo ◽  
Yasuhito Nakagawa ◽  
Keizo Waku
Keyword(s):  
Arachidonic Acid ◽  
Alveolar Macrophages ◽  
Cadmium Ions

Condensed Tannin Promotes the Release of Arachidonic Acid from Rabbit Resident Alveolar Macrophages

1992 ◽  
Vol 7 (2) ◽  
pp. 172-181 ◽  
Author(s):  
Teresa Kreofsky ◽  
Janis W. Schlager ◽  
Zvezdana Vuk-Pavlović ◽  
Robert T. Abraham ◽  
Michael S. Rohrbach
Keyword(s):  
Arachidonic Acid ◽  
Alveolar Macrophages ◽  
Condensed Tannin

Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages

Inflammation ◽  
1989 ◽  
Vol 13 (2) ◽  
pp. 233-244 ◽  
Author(s):  
W. W. Laegreid ◽  
S. M. Taylor ◽  
M. D. Englen ◽  
K. M. Straub ◽  
R. M. Silflow ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Alveolar Macrophages ◽  
Specific Production
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