Synthesis and receptor binding of 5-amino[3H]2methyl-3-isothiazolol ([3H]thiomuscimol), a specific GABAa agonist photoaffinity label

1995 ◽  
Vol 36 (9) ◽  
pp. 877-889 ◽  
Author(s):  
B. Frølund ◽  
B. Ebert ◽  
L. W. Lawrence ◽  
S. D. Hurt ◽  
P. Krogsgaard-Larsen
Keyword(s):  
Receptor Binding ◽  
Photoaffinity Label

Effect of amphetamine on dopamine D2 receptor binding in the primate brain with the agonist ligand [11C]MNPA

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S646-S646
Author(s):  
Nicholas Seneca ◽  
Sjoerd Finnema ◽  
Masanori Ichise ◽  
Balazs Gulyas ◽  
Håkan Wikstrom ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Dopamine D2 ◽  
Primate Brain

Antiproliferative and antiviral effects of mutated IFN-alpha with increased IFN receptor binding affinity

2011 ◽  
Vol 49 (01) ◽  
Author(s):  
MF Sprinzl ◽  
L Bührer ◽  
D Strand ◽  
G Schreiber ◽  
PR Galle ◽  
...  
Keyword(s):  
Binding Affinity ◽  
Receptor Binding ◽  
Receptor Binding Affinity ◽  
Ifn Alpha ◽  
Antiviral Effects

Decreased Dopamine D2/D3-Receptor Binding in the Temporal Lobe and the Bilateral Basal Ganglia in patients with Temporal Lobe Epilepsy

2012 ◽  
Vol 43 (01) ◽  
Author(s):  
VE Bernedo Paredes ◽  
H Schwartz ◽  
M Gartenschläger ◽  
M Gartenschläger ◽  
HG Buchholz ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Receptor Binding ◽  
D3 Receptor ◽  
Dopamine D2

Vergleich von Blutfluß und Benzodiazepin-Rezeptorverteilung bei fokaler Epilepsie: Vorläufige Ergebnisse einer SPECT-Studie

1989 ◽  
Vol 28 (05) ◽  
pp. 181-186
Author(s):  
A. Ludolph ◽  
O. Schober ◽  
G. Lottes ◽  
I. Böttger ◽  
H.-F. Beer ◽  
...  
Keyword(s):  
Human Brain ◽  
Receptor Binding ◽  
Brain Area ◽  
Brain Perfusion ◽  
Partial Epilepsy ◽  
Cerebral Lesion ◽  
Receptor Ligand ◽  
Receptor Mapping ◽  
Hmpao Spect ◽  
99Mtc Hmpao

99mTc-HMPAO-SPECT and SPECT with the 123I-labelled benzodiazepine (Bz) receptor ligand Ro 16-0154 were performed in 10 patients suffering from partial epilepsy, without cerebral lesion in MRT or CT. 2 h p.i. of Ro 16-0154 the distribution of activity correlated with the known distribution of Bz- receptors in the human brain. Perfusion and receptor-binding were found decreased in 7 patients of each study in the suspicious brain-area. 123l-labelled Ro 16-0154 is suitable for Bz-receptor mapping by SPECT. The decrease of Bz-receptor binding in epileptic foci, as described in PET-studies, was also detected by SPECT in 7 of 10 patients.

Cell cycle dependent modulation of insulin and IGF I receptor binding to human Burkitt type ALL cells

1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S81
Author(s):  
U. VETTER ◽  
W. HARTMANN ◽  
H. HITZLER ◽  
W. HEIT ◽  
J. SCHLICKENRIEDER ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Receptor Binding ◽  
Igf I ◽  
Cycle Dependent
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