A biophysical and computational study unraveling the molecular interaction mechanism of a new Janus kinase inhibitor Tofacitinib with bovine serum albumin

2016 ◽  
Vol 30 (6) ◽  
pp. e2601 ◽  
Author(s):  
Ali Saber Abdelhameed ◽  
Saima Nusrat ◽  
Mohammad Rehan Ajmal ◽  
Syed Mohammad Zakariya ◽  
Masihuz Zaman ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Molecular Interaction ◽  
Bovine Serum ◽  
Kinase Inhibitor ◽  
Computational Study ◽  
Interaction Mechanism ◽  
Janus Kinase ◽  
Janus Kinase Inhibitor

Exploring the interaction mechanism of a dicarboxamide fungicide, iprodione with bovine serum albumin

2019 ◽  
Vol 74 (5) ◽  
pp. 1633-1646
Author(s):  
Saad Tayyab ◽  
Loh Hui Min ◽  
Md. Zahirul Kabir ◽  
Salanee Kandandapani ◽  
Nor Farrah Wahidah Ridzwan ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Interaction Mechanism

Molecular interaction of cationic gemini surfactant with bovine serum albumin: A spectroscopic and molecular docking study

2014 ◽  
Vol 49 (4) ◽  
pp. 623-630 ◽  
Author(s):  
Muzaffar Ul Hassan Mir ◽  
Jitendra Kumar Maurya ◽  
Shahnawaz Ali ◽  
Shah Ubaid-ullah ◽  
Abbul Bashar Khan ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Molecular Interaction ◽  
Bovine Serum ◽  
Gemini Surfactant ◽  
Docking Study ◽  
Molecular Docking Study ◽  
Cationic Gemini Surfactant

Exploring the Binding Interaction Mechanism of Taxol in β-Tubulin and Bovine Serum Albumin: A Biophysical Approach

2019 ◽  
Vol 16 (2) ◽  
pp. 669-681 ◽  
Author(s):  
Subramani Karthikeyan ◽  
Ganesan Bharanidharan ◽  
Sriram Ragavan ◽  
Saravanan Kandasamy ◽  
Shanmugavel Chinnathambi ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Interaction Mechanism ◽  
Binding Interaction ◽  
Biophysical Approach ◽  
Β Tubulin

Spectroscopic and electrochemical studies on the molecular interaction between copper sulphide nanoparticles and bovine serum albumin

2017 ◽  
Vol 53 (1) ◽  
pp. 202-214 ◽  
Author(s):  
Mallappa Mahanthappa ◽  
Mohammed Azharuddin Savanur ◽  
Bijesh Puthusseri ◽  
Shivaraj Yellappa
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Molecular Interaction ◽  
Bovine Serum ◽  
Electrochemical Studies ◽  
Copper Sulphide

A multitechnique approach to probe the interaction of a therapeutic tyrosine kinase inhibitor nintedanib and bovine serum albumin

2017 ◽  
Vol 47 (7) ◽  
pp. 655-663 ◽  
Author(s):  
Ali Saber Abdelhameed ◽  
Saima Nusrat ◽  
Sanjhi Paliwal ◽  
Masihuz Zaman ◽  
Nida Zaidi ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Tyrosine Kinase ◽  
Serum Albumin ◽  
Tyrosine Kinase Inhibitor ◽  
Bovine Serum ◽  
Kinase Inhibitor

Interaction Mechanism between Bovine Serum Albumin and Polyethylene Glycol Revealed with Elastic Light Scattering Spectroscopy

2013 ◽  
Vol 704 ◽  
pp. 43-50
Author(s):  
Wen Zhi Zhang ◽  
Kuan Zhang ◽  
Jian Long Zheng ◽  
Hong Shu Chen ◽  
Wei Xing Chen ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Light Scattering ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Interaction Mechanism ◽  
Interaction Force ◽  
Elastic Light Scattering ◽  
Apparent Binding Constant ◽  
Light Scattering Spectroscopy

In order to gain deeper insight into the interaction mechanism between bovine serum albumin (BSA) and polyethylene glycol (PEG), the present work applied elastic light scattering (ELS) spectroscopy to investigate the interaction between BSA and PEG, and explore the effects of concentration and molecular weight of PEG on the interaction at physiological pH. The results showed that the interaction force existed between linear PEG and spherical BSA molecules was mainly hydrogen bonding. In addition, the apparent binding constant of system was evaluated by model calculation.

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