Editorial for “Longitudinal Sodium MRI of Multiple Sclerosis Lesions: Is There Added Value of Sodium Inversion Recovery MRI ?”

2021 ◽  
Author(s):  
Tomohisa Okada ◽  
Thai Akasaka
Keyword(s):  
Multiple Sclerosis ◽  
Inversion Recovery ◽  
Added Value ◽  
Sodium Mri

scholarly journals Longitudinal Sodium MRI of Multiple Sclerosis Lesions: Is there Added Value of Sodium Inversion Recovery MRI

2021 ◽  
Author(s):  
Angelika B. Mennecke ◽  
Armin M. Nagel ◽  
Konstantin Huhn ◽  
Ralf A. Linker ◽  
Manuel Schmidt ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Inversion Recovery ◽  
Added Value ◽  
Sodium Mri

scholarly journals The Added Value of Double Dose Gadolinium Enhanced 3D T2 Fluid-Attenuated Inversion Recovery for Evaluating Small Brain Metastases

2014 ◽  
Vol 55 (5) ◽  
pp. 1231 ◽  
Author(s):  
Sung Jun Ahn ◽  
Tae-Sub Chung ◽  
Jong-Hee Chang ◽  
Seung-Koo Lee
Keyword(s):  
Brain Metastases ◽  
Inversion Recovery ◽  
Added Value ◽  
Double Dose ◽  
Fluid Attenuated Inversion Recovery

Disease progression in multiple sclerosis: combining physicians’ and patients’ perspectives?

2010 ◽  
Vol 17 (2) ◽  
pp. 234-240 ◽  
Author(s):  
JJ Kragt ◽  
JM Nielsen ◽  
FAH van der Linden ◽  
CH Polman ◽  
BMJ Uitdehaag
Keyword(s):  
Multiple Sclerosis ◽  
Clinical Outcome ◽  
Disease Progression ◽  
Outcome Measures ◽  
Added Value ◽  
Impact Scale ◽  
Disability Status ◽  
The Impact ◽  
Nine Hole Peg Test ◽  
Combine Outcome

Background: To assess disease progression in multiple sclerosis (MS) several outcome measures are available. The interrelation of changes on different scales has not been studied extensively and the concept of combining scales has only recently been introduced in MS. Objective: To explore combining different clinical outcome measures in the evaluation of disease progression in MS. Methods: In 553 patients we studied the presence of relevant changes according to standard definitions on the Expanded Disability Status Scale (EDSS), Nine-Hole Peg Test (9HPT), Timed 25-Foot Walk (T25FW) and the Multiple Sclerosis Impact Scale (MSIS-29). We examined ‘exclusive worsening’ (worsening on one measure while not worsening on any other measure) and ‘opposing changes’ (worsening on one measure while improving on another measure). Finally, we investigated the impact of combining assessments. Results: Based on the EDSS alone, 140 patients progressed. However, almost twice as many (275) showed worsening on any of the clinical outcome measures. Exclusive worsening was observed in 37 patients on the EDSS, 13 on the 9HPT, 39 on the T25FW and 44 on the MSIS physical. Of all worsened patients 76 (28%) showed opposing changes, a phenomenon predominantly observed when combining physician-based and patient-derived outcome measures. Conclusion: When assessing disease progression in MS, sensitivity to change can be increased by combining different outcome measures. The added value is especially present when combining measures from different perspectives. However, further research is needed to evaluate the optimal way to combine outcome measures before implementing this strategy in clinical studies.

A comparison of sagittal short T1 inversion recovery and T2-weighted FSE sequences for detection of multiple sclerosis spinal cord lesions

2013 ◽  
Vol 129 (3) ◽  
pp. 198-203 ◽  
Author(s):  
N. B. Nayak ◽  
R. Salah ◽  
J. C. Huang ◽  
G. M. Hathout
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Inversion Recovery ◽  
Spinal Cord Lesions

scholarly journals Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla

2010 ◽  
Vol 20 (7) ◽  
pp. 1675-1683 ◽  
Author(s):  
Birgit Simon ◽  
Stephan Schmidt ◽  
Carsten Lukas ◽  
Jürgen Gieseke ◽  
Frank Träber ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mr Imaging ◽  
Inversion Recovery ◽  
3 Tesla ◽  
Double Inversion Recovery ◽  
Cortical Lesions ◽  
In Vivo Detection
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