Structural characterization ofin vitrorat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS

Guodong Chen; Ibrahim Daaro; Birendra N. Pramanik; John J. Piwinski

doi:10.1002/jms.1498

Structural characterization ofin vitrorat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS

Journal of Mass Spectrometry ◽

10.1002/jms.1498 ◽

2009 ◽

Vol 44 (2) ◽

pp. 203-213 ◽

Cited By ~ 30

Author(s):

Guodong Chen ◽

Ibrahim Daaro ◽

Birendra N. Pramanik ◽

John J. Piwinski

Keyword(s):

Mass Spectrometer ◽

Structural Characterization ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hybrid Mass Spectrometer ◽

Hydrogen Deuterium

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Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

Journal of Mass Spectrometry ◽

10.1002/jms.1943 ◽

2011 ◽

Vol 46 (8) ◽

pp. 725-733 ◽

Cited By ~ 23

Author(s):

Tian Liu ◽

Fuying Du ◽

Yakun Wan ◽

Fanping Zhu ◽

Jie Xing

Keyword(s):

Phase I ◽

Mass Spectrometer ◽

Rapid Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hybrid Mass Spectrometer ◽

Hydrogen Deuterium ◽

Phase I And Ii ◽

Exchange Technique

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Online Hydrogen/Deuterium Exchange Performed in the Ion Mobility Cell of a Hybrid Mass Spectrometer

Analytical Chemistry ◽

10.1021/ac901736j ◽

2009 ◽

Vol 81 (22) ◽

pp. 9365-9371 ◽

Cited By ~ 14

Author(s):

Kornél Nagy ◽

Karine Redeuil ◽

Serge Rezzi

Keyword(s):

Mass Spectrometer ◽

Ion Mobility ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hybrid Mass Spectrometer ◽

Hydrogen Deuterium

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Structural identification of trace level enol tautomer impurity by on-line hydrogen/deuterium exchange HR-LC/MS in a LTQ-Orbitrap hybrid mass spectrometer

Journal of Mass Spectrometry ◽

10.1002/jms.1232 ◽

2007 ◽

Vol 42 (7) ◽

pp. 967-970 ◽

Cited By ~ 14

Author(s):

Guodong Chen ◽

Anatoliy Khusid ◽

Ibrahim Daaro ◽

Patrick Irish ◽

Birendra N. Pramanik

Keyword(s):

Mass Spectrometer ◽

Structural Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Trace Level ◽

Hybrid Mass Spectrometer ◽

Hydrogen Deuterium ◽

On Line ◽

Enol Tautomer

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Hydrogen-deuterium exchange studies utilizing a thermospray mass spectrometer interface

Analytical Chemistry ◽

10.1021/ac00170a021 ◽

1988 ◽

Vol 60 (19) ◽

pp. 2090-2095 ◽

Cited By ~ 31

Author(s):

Marshall M. Siegel

Keyword(s):

Mass Spectrometer ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Hydrogen Deuterium

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Oligonucleotide Gas-Phase Hydrogen/Deuterium Exchange with D2S in the Collision Cell of a Quadrupole-Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

Analytical Chemistry ◽

10.1021/ac0713095 ◽

2007 ◽

Vol 79 (20) ◽

pp. 7893-7898 ◽

Cited By ~ 7

Author(s):

Jingjie Mo ◽

Kristina Håkansson

Keyword(s):

Fourier Transform ◽

Gas Phase ◽

Mass Spectrometer ◽

Cyclotron Resonance ◽

Deuterium Exchange ◽

Collision Cell ◽

Ion Cyclotron Resonance ◽

Hydrogen Deuterium Exchange ◽

Ion Cyclotron ◽

Hydrogen Deuterium

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Structural Characterization of Histone Octamers at Varied Salt Concentrations Using Hydrogen‐Deuterium Exchange Mass Spectrometry

The FASEB Journal ◽

10.1096/fasebj.2020.34.s1.06177 ◽

2020 ◽

Vol 34 (S1) ◽

pp. 1-1

Author(s):

Adam Timmerman

Keyword(s):

Mass Spectrometry ◽

Structural Characterization ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry ◽

Histone Octamers

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Gas phase hydrogen/deuterium exchange reactions of peptide ions in a quadrupole ion trap mass spectrometer

Proteins Structure Function and Bioinformatics ◽

10.1002/(sici)1097-0134(199705)28:1<53::aid-prot5>3.0.co;2-k ◽

1997 ◽

Vol 28 (1) ◽

pp. 53-58 ◽

Cited By ~ 35

Author(s):

Igor A. Kaltashov ◽

Vladimir M. Doroshenko ◽

Robert J. Cotter

Keyword(s):

Gas Phase ◽

Mass Spectrometer ◽

Ion Trap ◽

Quadrupole Ion Trap ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Peptide Ions ◽

Exchange Reactions ◽

Ion Trap Mass Spectrometer ◽

Hydrogen Deuterium

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Online Hydrogen-Deuterium Exchange and a Tandem-Quadrupole Time-of-Flight Mass Spectrometer Coupled with Liquid Chromatography for Metabolite Identification in Drug Metabolism

Journal of Chromatographic Science ◽

10.1093/chromsci/41.8.398 ◽

2003 ◽

Vol 41 (8) ◽

pp. 398-404 ◽

Cited By ~ 32

Author(s):

A.- E. F. Nassar

Keyword(s):

Liquid Chromatography ◽

Drug Metabolism ◽

Mass Spectrometer ◽

Time Of Flight ◽

Metabolite Identification ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Flight Mass Spectrometer ◽

Hydrogen Deuterium ◽

Tandem Quadrupole

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Fast Comparative Structural Characterization of Intact Therapeutic Antibodies Using Hydrogen–Deuterium Exchange and Electron Transfer Dissociation

Analytical Chemistry ◽

10.1021/ac504809r ◽

2015 ◽

Vol 87 (12) ◽

pp. 5884-5890 ◽

Cited By ~ 20

Author(s):

Jingxi Pan ◽

Suping Zhang ◽

Albert Chou ◽

Darryl B. Hardie ◽

Christoph H. Borchers

Keyword(s):

Electron Transfer ◽

Structural Characterization ◽

Electron Transfer Dissociation ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Therapeutic Antibodies ◽

Hydrogen Deuterium ◽

Comparative Structural Characterization

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Protein Structural Characterization by Hydrogen/Deuterium Exchange Mass Spectrometry with Top-down Electron Capture Dissociation

Bulletin of the Korean Chemical Society ◽

10.5012/bkcs.2013.34.5.1401 ◽

2013 ◽

Vol 34 (5) ◽

pp. 1401-1406 ◽

Cited By ~ 3

Author(s):

Hai Dong Yu ◽

Seonghee Ahn ◽

Byungjoo Kim

Keyword(s):

Mass Spectrometry ◽

Electron Capture ◽

Electron Capture Dissociation ◽

Structural Characterization ◽

Deuterium Exchange ◽

Hydrogen Deuterium Exchange ◽

Top Down ◽

Exchange Mass Spectrometry ◽

Hydrogen Deuterium ◽

Deuterium Exchange Mass Spectrometry

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