Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

Hydrogen Deuterium ◽

Phase I And Ii ◽

Exchange Technique

Structural characterization ofin vitrorat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS

Journal of Mass Spectrometry ◽

10.1002/jms.1498 ◽

2009 ◽

Vol 44 (2) ◽

pp. 203-213 ◽

Cited By ~ 30

Author(s):

Guodong Chen ◽

Ibrahim Daaro ◽

Birendra N. Pramanik ◽

John J. Piwinski

Keyword(s):

Mass Spectrometer ◽

Structural Characterization ◽

Deuterium Exchange ◽

Online Hydrogen/Deuterium Exchange Performed in the Ion Mobility Cell of a Hybrid Mass Spectrometer

Analytical Chemistry ◽

10.1021/ac901736j ◽

2009 ◽

Vol 81 (22) ◽

pp. 9365-9371 ◽

Cited By ~ 14

Author(s):

Kornél Nagy ◽

Karine Redeuil ◽

Serge Rezzi

Keyword(s):

Mass Spectrometer ◽

Ion Mobility ◽

Deuterium Exchange ◽

Structural identification of trace level enol tautomer impurity by on-line hydrogen/deuterium exchange HR-LC/MS in a LTQ-Orbitrap hybrid mass spectrometer

Journal of Mass Spectrometry ◽

10.1002/jms.1232 ◽

2007 ◽

Vol 42 (7) ◽

pp. 967-970 ◽

Cited By ~ 14

Author(s):

Guodong Chen ◽

Anatoliy Khusid ◽

Ibrahim Daaro ◽

Patrick Irish ◽

Birendra N. Pramanik

Keyword(s):

Mass Spectrometer ◽

Structural Identification ◽

Deuterium Exchange ◽

Trace Level ◽

Hydrogen Deuterium ◽

On Line ◽

Enol Tautomer

Metabolite identification of artemether by data-dependent accurate mass spectrometric analysis using an LTQ-Orbitrap hybrid mass spectrometer in combination with the online hydrogen/deuterium exchange technique

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.5214 ◽

2011 ◽

Vol 25 (21) ◽

pp. 3303-3313 ◽

Cited By ~ 15

Author(s):

Tian Liu ◽

Fuying Du ◽

Fanping Zhu ◽

Jie Xing

Keyword(s):

Mass Spectrometer ◽

Metabolite Identification ◽

Mass Spectrometric ◽

Mass Spectrometric Analysis ◽

Accurate Mass ◽

Spectrometric Analysis ◽

Hydrogen Deuterium ◽

Exchange Technique

Hydrogen-deuterium exchange studies utilizing a thermospray mass spectrometer interface

Analytical Chemistry ◽

10.1021/ac00170a021 ◽

1988 ◽

Vol 60 (19) ◽

pp. 2090-2095 ◽

Cited By ~ 31

Author(s):

Marshall M. Siegel

Keyword(s):

Mass Spectrometer ◽

Deuterium Exchange ◽

Oligonucleotide Gas-Phase Hydrogen/Deuterium Exchange with D2S in the Collision Cell of a Quadrupole-Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

Analytical Chemistry ◽

10.1021/ac0713095 ◽

2007 ◽

Vol 79 (20) ◽

pp. 7893-7898 ◽

Cited By ~ 7

Author(s):

Jingjie Mo ◽

Kristina Håkansson

Keyword(s):

Fourier Transform ◽

Gas Phase ◽

Mass Spectrometer ◽

Cyclotron Resonance ◽

Deuterium Exchange ◽

Collision Cell ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron ◽

Liquid chromatography/quadrupole time-of-flight mass spectrometry in combination with online hydrogen/deuterium exchange technique for structural elucidation of phase I metabolites ofiso-phenylcyclopentylamine in rat bile

Biomedical Chromatography ◽

10.1002/bmc.3170 ◽

2014 ◽

Vol 28 (10) ◽

pp. 1335-1344 ◽

Cited By ~ 2

Author(s):

Xiaoxue Liu ◽

Suilou Wang ◽

Li Ding ◽

Xiaoping Chen ◽

Wenbin Shen ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Phase I ◽

Time Of Flight ◽

Structural Elucidation ◽

Flight Mass Spectrometry ◽

Hydrogen Deuterium ◽

Rat Bile ◽

Exchange Technique

Gas phase hydrogen/deuterium exchange reactions of peptide ions in a quadrupole ion trap mass spectrometer

Proteins Structure Function and Bioinformatics ◽

10.1002/(sici)1097-0134(199705)28:1<53::aid-prot5>3.0.co;2-k ◽

1997 ◽

Vol 28 (1) ◽

pp. 53-58 ◽

Cited By ~ 35

Author(s):

Igor A. Kaltashov ◽

Vladimir M. Doroshenko ◽

Robert J. Cotter

Keyword(s):

Gas Phase ◽

Mass Spectrometer ◽

Ion Trap ◽

Quadrupole Ion Trap ◽

Deuterium Exchange ◽

Peptide Ions ◽

Exchange Reactions ◽

Ion Trap Mass Spectrometer ◽

Online Hydrogen-Deuterium Exchange and a Tandem-Quadrupole Time-of-Flight Mass Spectrometer Coupled with Liquid Chromatography for Metabolite Identification in Drug Metabolism

Journal of Chromatographic Science ◽

10.1093/chromsci/41.8.398 ◽

2003 ◽

Vol 41 (8) ◽

pp. 398-404 ◽

Cited By ~ 32

Author(s):

A.- E. F. Nassar

Keyword(s):

Liquid Chromatography ◽

Drug Metabolism ◽

Mass Spectrometer ◽

Time Of Flight ◽

Metabolite Identification ◽

Deuterium Exchange ◽

Flight Mass Spectrometer ◽

Hydrogen Deuterium ◽

Tandem Quadrupole

Fragmentation study on the phenolic alkaloid neferine and its analogues with anti-HIV activities by electrospray ionization tandem mass spectrometry with hydrogen/deuterium exchange and its application for rapid identification ofin vitro microsomal metabolites of neferine

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3070 ◽

2007 ◽

Vol 21 (13) ◽

pp. 2120-2128 ◽

Cited By ~ 27

Author(s):

Hui Zhou ◽

Huidi Jiang ◽

Tongwei Yao ◽

Su Zeng

Keyword(s):

Mass Spectrometry ◽

Tandem Mass Spectrometry ◽

Electrospray Ionization ◽

Rapid Identification ◽

Deuterium Exchange ◽

Tandem Mass ◽

Ionization Tandem Mass Spectrometry

Hydrogen Deuterium ◽

Anti Hiv ◽