HPV E6/E7 mRNA versus HPV DNA biomarker in cervical cancer screening of a group of Macedonian women

2015 ◽  
Vol 87 (9) ◽  
pp. 1578-1586 ◽  
Author(s):  
Sotirija Duvlis ◽  
Katerina Popovska-Jankovic ◽  
Zorica Sarafinovska Arsova ◽  
Shaban Memeti ◽  
Zaneta Popeska ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Hpv Dna ◽  
Hpv E6

scholarly journals The Potential Benefits of HPV E6/E7 mRNA Test in Cervical Cancer Screening in China

2020 ◽  
Vol 10 ◽  
Author(s):  
Shao-Kai Zhang ◽  
Zhen Guo ◽  
Peng Wang ◽  
Le-Ni Kang ◽  
Man-Man Jia ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Hpv E6 ◽  
Potential Benefits

scholarly journals Genotypes distribution of human papillomavirus in cervical samples of Ecuadorian women

2016 ◽  
Vol 19 (1) ◽  
pp. 160-166 ◽  
Author(s):  
Gustavo David García Muentes ◽  
Lindsay Karen García Rodríguez ◽  
Ramiro Israel Burgos Galarraga ◽  
Franklin Almeida Carpio ◽  
Juan Carlos Ruiz Cabezas
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Gynecological Cancer ◽  
Hpv Infection ◽  
Multiple Infections ◽  
Hpv 16 ◽  
Hpv Dna ◽  
Hpv 18

ABSTRACT: Introduction: Human papillomavirus (HPV) is considered a necessary causative agent for developing oropharyngeal, anal and cervical cancer. Among women in Ecuadorian population, cervical cancer ranks as the second most common gynecological cancer. Not many studies about HPV burden have been published in Ecuador, and genotypes distribution has not been established yet. The little data available suggest the presence of other genotypes different than 16 and 18. Objectives: In the present study, we attempt to estimate the prevalence of HPV 16, HPV 18 and other 35 genotypes among Ecuadorian women undergoing cervical cancer screening. The overall prevalence of HPV infection was also estimated. Methods: Routine cervical samples were analyzed using Linear Array(r) HPV Genotyping test (Roche). Results: A total of 1,581 cervical samples obtained from Ecuadorian women undergoing cervical cancer screening were included in this study. HPV DNA was detected in 689 cervical samples (43.58%). Of these samples, 604 (38.20%) were positive for a single HPV genotype, while another 85 (5.37%) samples were positive for multiple HPV types. Genotype 16 (5.50%) resulted in the most frequently detected type in both single and multiple infections. HPV 33 (4.55%) and HPV 11 (3.80%) occupied the second and the third place in frequency among all detected genotypes. Conclusions: Viral genotypes different from HPV 16 and HPV 18 are frequently detected among Ecuadorian women. The overall prevalence of HPV resulted higher than the one reported in other South American countries with a greater burden in the second and third decades of life.

scholarly journals P824 Accuracy of cervical cancer screening using a self-collected vial for HPV DNA testing among adult women in sub-saharan africa

2019 ◽  
Author(s):  
Zita Aleyo Nodjikouambaye ◽  
Damtheou Sadjoli ◽  
Ralph Sydney Mboumba Bouassa ◽  
Hélène Péré ◽  
David Veyer ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Sub Saharan Africa ◽  
Adult Women ◽  
Dna Testing ◽  
Hpv Dna ◽  
Hpv Dna Testing ◽  
Sub Saharan

Home-based urinary HPV DNA testing in women who do not attend cervical cancer screening clinics

2015 ◽  
Vol 71 (3) ◽  
pp. 377-384 ◽  
Author(s):  
Alexandra Ducancelle ◽  
Justine Reiser ◽  
Adeline Pivert ◽  
Hélène Le Guillou-Guillemette ◽  
Anne Sophie Le Duc-Banaszuk ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Dna Testing ◽  
Hpv Dna ◽  
Hpv Dna Testing ◽  
Home Based

scholarly journals HPV DNA Testing in Cervical Cancer Screening

JAMA ◽  
2000 ◽  
Vol 283 (1) ◽  
pp. 87 ◽  
Author(s):  
Mark Schiffman ◽  
Rolando Herrero ◽  
Allan Hildesheim ◽  
Mark E. Sherman ◽  
Maria Bratti ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Dna Testing ◽  
Hpv Dna ◽  
Hpv Dna Testing

Oncogenic HPV-DNA testing alone as cervical cancer screening in high-risk population of Southern Mexico

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 16519-16519
Author(s):  
F. Gutierrez-Delgado ◽  
J. E. Enriquez-Freire ◽  
H. Leon-Velasco ◽  
J. A. Manzur-Perez ◽  
A. Baron-Rojas ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
High Risk ◽  
Cervical Cancer Screening ◽  
High Risk Population ◽  
Dna Testing ◽  
Southern Mexico ◽  
Hpv Dna ◽  
Hpv Dna Testing ◽  
Oncogenic Hpv

scholarly journals The prevalence of hrHPV among the isolated community in the Highland of Bario, Sarawak, East Malaysia

2019 ◽  
Author(s):  
Abigail Rembui Jerip ◽  
Mardiana Kipli ◽  
Cheng-Siang Tan
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Outreach Program ◽  
Low Resource Settings ◽  
Dna Test ◽  
Hpv Dna ◽  
Low Resource ◽  
Cervical Swab

Abstract Background Malaysia has introduced the free Pap smear as the primary cervical cancer screening program since the 1960s but has only achieved the national coverage of 22%. The coverage would be much lower in the rural communities especially in Sarawak where many villages are still inaccessible by road, and communities are living in low resource settings. In this study, we have evaluated Qiagen’s careHPV system as a point-of-care HPV diagnostic test together with the visualization using acetic acid (VIA) in the isolated community in the Highland of Bario which are predominantly from the Kelabit ethnicity. Methods Women attending the cervical cancer outreach program were recruited. Consent was obtained and a cervical swab was clinician-collected and screened for High-risk HPV DNA using the careHPV system. Cervical examination using VIA was offered to all women age <50-year. hrHPV positive women were recruited during their follow-up session and the second cervical swab was collected for HPV genotyping using consensus primer-nested PCR to elucidate the infecting HPV genotypes. Results Seventy-five women from the age of 27-83 (mean age 55) attended the cervical cancer screening clinic and 8% (n=6/75) of them were positive for hrHPV. Only 33 women were screened using VIA and 21.2% (n=7/33) were found to be positive. A majority of the women (58.6%) were above the age of 50-year and not recommended for VIA to be performed. Thus, it was not feasible to correlate the results obtained from the HPV DNA test and VIA. Only four hrHPV positive women returned for follow-up and genotyping revealed HPV52 in 2 of four women tested suggesting that HPV52 may be the predominant genotype in Bario. Conclusions The careHPV system is portable and can be used in low resource settings as long as reliable electricity is available. We found that careHPV DNA test is more objective compared to VIA and can be used to screen women outside the recommended eligible age. This is especially true for older women in the rural who have never had any form of cervical cancer screening before.

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