The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals

2010 ◽  
Vol 99 (4) ◽  
pp. 1674-1692 ◽  
Author(s):  
Tsutomu Arakawa ◽  
Daisuke Ejima ◽  
Tiansheng Li ◽  
John S. Philo
Keyword(s):  
Phase Composition ◽  
Size Exclusion Chromatography ◽  
Mobile Phase ◽  
Critical Role ◽  
Size Exclusion ◽  
Mobile Phase Composition ◽  
Exclusion Chromatography ◽  
Protein Pharmaceuticals

Effect of mobile phase composition on the analysis of aggregates of antibody drug conjugates (ADCs) using size exclusion chromatography

2018 ◽  
Vol 10 (9) ◽  
pp. 938-941 ◽  
Author(s):  
Rabin Neupane ◽  
Malin Källsten ◽  
Fredrik Lehmann ◽  
Jonas Bergquist
Keyword(s):  
Phase Composition ◽  
Size Exclusion Chromatography ◽  
Mobile Phase ◽  
Size Exclusion ◽  
Mobile Phase Composition ◽  
Antibody Drug Conjugate ◽  
Aggregate Analysis ◽  
Drug Conjugates ◽  
Exclusion Chromatography ◽  
Antibody Drug

In this study, the effect of mobile phase composition for size exclusion chromatography (SEC) on antibody drug conjugate (ADC) aggregate analysis was investigated.

Size-exclusion chromatography of coal extracts using pyridine as a mobile phase

1988 ◽  
Vol 2 (1) ◽  
pp. 32-36 ◽  
Author(s):  
David H. Buchanan ◽  
Linda C. Warfel ◽  
Shawn Bailey ◽  
Douglas Lucas
Keyword(s):  
Size Exclusion Chromatography ◽  
Mobile Phase ◽  
Size Exclusion ◽  
Exclusion Chromatography
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