Characterizing the host response to rhPDGF‐BB in a rat spinal arthrodesis model

Characterizing the Host Response to rhBMP-2 in a Rat Spinal Arthrodesis Model

Spine ◽

10.1097/brs.0b013e31828cb977 ◽

2013 ◽

Vol 38 (12) ◽

pp. E691-E698 ◽

Cited By ~ 19

Author(s):

Wellington K. Hsu ◽

Mahesh Polavarapu ◽

Rehan Riaz ◽

Andrew C. Larson ◽

Jared J. Diegmueller ◽

...

Keyword(s):

Host Response ◽

Spinal Arthrodesis

Signature of the Host Response to a Respiratory Viral Infection, in the Prediction of Bronchiolitis Obliterans

Case Medical Research ◽

10.31525/ct1-nct04099082 ◽

2019 ◽

Author(s):

Keyword(s):

Viral Infection ◽

Bronchiolitis Obliterans ◽

Host Response ◽

Respiratory Viral Infection

Faculty Opinions recommendation of Expression profiling of the host response to bacterial infection: the transition from basal to induced defence responses in RPM1-mediated resistance.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1012366.185340 ◽

2003 ◽

Author(s):

John W Mansfield

Keyword(s):

Bacterial Infection ◽

Expression Profiling ◽

Host Response ◽

Induced Defence ◽

Defence Responses

Faculty Opinions recommendation of Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718369677.793495424 ◽

2014 ◽

Author(s):

Vernon Carruthers

Keyword(s):

Host Response

Faculty Opinions recommendation of Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725339982.793504507 ◽

2015 ◽

Author(s):

Guy Zimmerman

Keyword(s):

B Cell ◽

Host Response ◽

Secondary Infection ◽

Cell Responses ◽

B Cell Responses

Faculty Opinions recommendation of Computational analysis reveals a key regulator of cryptococcal virulence and determinant of host response.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726298738.793520435 ◽

2016 ◽

Author(s):

Jim Kronstad

Keyword(s):

Host Response ◽

Computational Analysis

Preconditioning Human Adipose-Derived Stromal Cells on Decellularized Adipose Tissue Scaffolds within a Perfusion Bioreactor Modulates Cell Phenotype and Promotes a Pro-Regenerative Host Response

SSRN Electronic Journal ◽

10.2139/ssrn.3732500 ◽

2020 ◽

Author(s):

Tim T.Y. Han ◽

John T. Walker ◽

Aaron Grant ◽

Gregory A. Dekaban ◽

Lauren Elizabeth Flynn

Keyword(s):

Adipose Tissue ◽

Stromal Cells ◽

Host Response ◽

Tissue Scaffolds ◽

Cell Phenotype ◽

Perfusion Bioreactor ◽

Adipose Derived Stromal Cells

The complement system: its importance in the host response to viral infection.

Microbiological Reviews ◽

10.1128/mr.46.1.71-85.1982 ◽

1982 ◽

Vol 46 (1) ◽

pp. 71-85

Author(s):

R L Hirsch

Keyword(s):

Viral Infection ◽

Complement System ◽

Host Response ◽

The Complement System

Elastase and lactoferrin in gingival crevicular fluid: possible indicators of a granulocyte-associated specific host response

Journal of Periodontal Research ◽

10.1111/j.1600-0765.1994.tb01222.x ◽

1994 ◽

Vol 29 (4) ◽

pp. 276-282 ◽

Cited By ~ 43

Author(s):

A. Gustafsson ◽

B. Asman ◽

K. Bergstrom

Keyword(s):

Host Response ◽

Gingival Crevicular Fluid ◽

Specific Host ◽

Crevicular Fluid

Sepsis as a Pan-Endocrine Illness—Endocrine Disorders in Septic Patients

Journal of Clinical Medicine ◽

10.3390/jcm10102075 ◽

2021 ◽

Vol 10 (10) ◽

pp. 2075

Author(s):

Weronika Wasyluk ◽

Martyna Wasyluk ◽

Agnieszka Zwolak

Keyword(s):

Host Response ◽

Peripheral Resistance ◽

Endocrine System ◽

Endocrine Disorders ◽

Hormonal Changes ◽

Adrenergic Stimulation ◽

Hypothalamic Amenorrhea ◽

Somatotropic Axis ◽

Almost All ◽

Triiodothyronine Concentration

Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. One of the elements of dysregulated host response is an endocrine system disorder. Changes in its functioning in the course of sepsis affect almost all hormonal axes. In sepsis, a function disturbance of the hypothalamic–pituitary–adrenal axis has been described, in the range of which the most important seems to be hypercortisolemia in the acute phase. Imbalance in the hypothalamic–pituitary–thyroid axis is also described. The most typical manifestation is a triiodothyronine concentration decrease and reverse triiodothyronine concentration increase. In the somatotropic axis, a change in the secretion pattern of growth hormone and peripheral resistance to this hormone has been described. In the hypothalamic–pituitary–gonadal axis, the reduction in testosterone concentration in men and the stress-induced “hypothalamic amenorrhea” in women have been described. Catecholamine and β-adrenergic stimulation disorders have also been reported. Disorders in the endocrine system are part of the “dysregulated host response to infection”. They may also affect other components of this dysregulated response, such as metabolism. Hormonal changes occurring in the course of sepsis require further research, not only in order to explore their potential significance in therapy, but also due to their promising prognostic value.