Expanding the applicability of magnetic ionic liquids for multiclass determination in biological matrices based on dispersive liquid–liquid microextraction and HPLC with diode array detector analysis

A rapid and reliable dispersive liquid–liquid microextraction (DLLME) method was coupled with field-amplified sample injection (FASI) in capillary electrophoresis with a diode array detector for the quantification of verapamil enantiomers in human plasma samples.

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In situ formation of hydrophobic magnetic ionic liquids for dispersive liquid-liquid microextraction

Journal of Chromatography A ◽

10.1016/j.chroma.2018.12.032 ◽

2019 ◽

Vol 1588 ◽

pp. 8-16 ◽

Cited By ~ 17

Author(s):

María J. Trujillo-Rodríguez ◽

Jared L. Anderson

Keyword(s):

Ionic Liquids ◽

Magnetic Ionic Liquids ◽

In Situ Formation ◽

Dispersive Liquid Liquid Microextraction ◽

Liquid Microextraction

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Ultrasound–Vortex-Assisted Dispersive Liquid–Liquid Microextraction Combined with High Performance Liquid Chromatography–Diode Array Detection for Determining UV Filters in Cosmetics and the Human Stratum Corneum

Molecules ◽

10.3390/molecules25204642 ◽

2020 ◽

Vol 25 (20) ◽

pp. 4642

Author(s):

Fang-Yi Liao ◽

Yu-Lin Su ◽

Jing-Ru Weng ◽

Ying-Chi Lin ◽

Chia-Hsien Feng

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Stratum Corneum ◽

High Performance ◽

Array Detector ◽

Diode Array ◽

Uv Filters ◽

Human Stratum Corneum ◽

Dispersive Liquid Liquid Microextraction ◽

Liquid Microextraction

This study explores the amounts of common chemical ultraviolet (UV) filters (i.e., avobenzone, bemotrizinol, ethylhexyl triazone, octocrylene, and octyl methoxycinnamate) in cosmetics and the human stratum corneum. An ultrasound–vortex-assisted dispersive liquid–liquid microextraction (US–VA–DLLME) method with a high-performance liquid chromatography–diode array detector was used to analyze UV filters. A bio-derived solvent (i.e., anisole) was used as the extractant in the US–VA–DLLME procedure, along with methanol as the dispersant, a vortexing time of 4 min, and ultrasonication for 3 min. The mass-transfer rate of the extraction process was enhanced due to vortex-ultrasound combination. Various C18 end-capped columns were used to investigate the separation characteristics of the UV filters, with XBridge BEH or CORTECS selected as the separation column. Calibration curves were constructed in the 0.05–5 μg/mL (all filters except octocrylene) and 0.1–10 μg/mL (octocrylene) ranges, and excellent analytical linearities with coefficients of determination (r2) above 0.998. The developed method was successfully used to analyze sunscreen. Moreover, experiments were designed to simulate the sunscreen-usage habits of consumers, and the cup method was used to extract UV filters from the human stratum corneum. The results suggest that a makeup remover should be employed to remove water-in-oil sunscreens from skin.

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