The natural history of recoverable vocal fold paralysis: Implications for kinetics of reinnervation

AbstractWe report a case of bilateral abductor vocal fold paralysis due to myasthenia gravis in a 61-year-old man who presented with stridor requiring tracheostomy. The stridor had been preceded by several weeks' history of diplopia.

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Kinetics of HIV-1 specific cytotoxic T lymphocyte responses and viral load in the natural history of HIV-1 infection

Immunology Letters ◽

10.1016/s0165-2478(97)85095-x ◽

1997 ◽

Vol 56 ◽

pp. 25

Author(s):

O. Pontesilli ◽

M.R. Klein ◽

S.R. Kerkhof-Garde ◽

N. Pakker ◽

F. de Wolf ◽

...

Keyword(s):

Viral Load ◽

Natural History ◽

T Lymphocyte ◽

Cytotoxic T Lymphocyte ◽

History Of ◽

Lymphocyte Responses ◽

Kinetics Of ◽

Hiv 1

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Kinetics of HIV-1 specific cytotoxic T lymphocyte responses and viral load in the natural history of HIV-1 infection

Immunology Letters ◽

10.1016/s0165-2478(97)86933-7 ◽

1997 ◽

Vol 56 (1-3) ◽

pp. 25

Author(s):

O Pontesilli

Keyword(s):

Viral Load ◽

Natural History ◽

T Lymphocyte ◽

Cytotoxic T Lymphocyte ◽

History Of ◽

Lymphocyte Responses ◽

Kinetics Of ◽

Hiv 1

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Hoarseness due to Mycobacterium kansasii

The Journal of Laryngology & Otology ◽

10.1017/s0022215108003393 ◽

2008 ◽

Vol 123 (5) ◽

pp. 569-571 ◽

Cited By ~ 2

Author(s):

D Wray ◽

M O Oko ◽

D A R Boldy ◽

M T Butt

Keyword(s):

Weight Loss ◽

World Literature ◽

Vocal Fold ◽

Sputum Sample ◽

Vocal Folds ◽

Vocal Fold Paralysis ◽

Mycobacterium Kansasii ◽

Unilateral Vocal Fold Paralysis ◽

Abnormal Chest ◽

History Of

AbstractObjective:To present a case of unilateral vocal fold paralysis due to Mycobacterium kansasii induced pressure on the left recurrent laryngeal nerve, a specific aetiology not previously reported in the world literature.Case report:A 57-year-old Caucasian man presented with a short history of productive cough, fever, hoarseness and 14-kg weight loss. He was a smoker, had an abnormal chest X-ray and was human immunodeficiency virus negative. A sputum sample was positive on direct microscopy for acid fast bacilli. Initially, the patient was treated with Rifater (rifampicin, isoniazid and pyrazinamide) and ethambutol. Mycobacterium kansasii was isolated and proved sensitive to this antimycobacterial treatment. Nasoendoscopy revealed diminished movement of the left vocal fold, and a computed tomography scan showed enlarged mediastinal lymph nodes anterior to the aortic arch. After three months of antimycobacterial treatment, the vocal folds were fully mobile at repeat nasoendoscopy, and this coincided with gradual resolution of the patient's hoarseness and weight loss.Conclusions:There are many causes of unilateral vocal fold paralysis. This case illustrates the importance of anatomical knowledge in reaching a diagnosis, and also presents the first reported case of Mycobacterium kansasii creating this clinical picture.

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Type I Posterior Glottic Stenosis: Natural History and In-Office Management

Annals of Otology Rhinology & Laryngology ◽

10.1177/0003489419854777 ◽

2019 ◽

Vol 128 (11) ◽

pp. 1073-1077 ◽

Cited By ~ 2

Author(s):

Valeria Silva Merea ◽

Babak Sadoughi

Keyword(s):

Natural History ◽

Treatment Outcomes ◽

Vocal Fold ◽

Ktp Laser ◽

Type I ◽

Laryngeal Function ◽

Prolonged Intubation ◽

Office Management ◽

Aged Woman ◽

History Of

Objectives: To review the natural history of type I posterior glottic stenosis (PGS-I) and its treatment outcomes through a case presentation and demonstrate the feasibility of in-office management of PGS-I. Methods: The case of a middle-aged woman who developed PGS-I after prolonged intubation is presented. A review of the literature on management and treatment outcomes of PGS-I is also performed. Results: Initially presenting with a large granuloma that failed conservative management, the patient deferred surgical intervention and developed unilateral vocal fold hypomobility with posterior glottic synechia. The adhesion was successfully ablated in the office with potassium-titanyl-phosphate (KTP) laser; however, vocal fold hypomobility persisted after treatment. Conclusions: This case illustrates the natural history of the development of PGS-I, demonstrates the feasibility of office-based management of this condition, and provides further evidence that lysis of PGS-I synechia does not uniformly lead to restoration of normal laryngeal function and mobility.

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A UNIQUE CASE OF BILATERAL VOCAL FOLD PARALYSIS FOLLOWING SPINAL ANAESTHESIA

EUREKA Health Sciences ◽

10.21303/2504-5679.2020.001315 ◽

2020 ◽

Vol 3 ◽

pp. 3-5

Author(s):

Manasij Mitra ◽

Nupur Biswas ◽

Kumar Shailendra ◽

Anil Chandra Jain ◽

Maitraye Basu

Keyword(s):

Spinal Anaesthesia ◽

Cranial Nerve ◽

Vocal Fold ◽

Case Reports ◽

Cranial Nerves ◽

Trochanteric Fracture ◽

Vocal Fold Paralysis ◽

Cranial Nerve Palsies ◽

Bilateral Vocal Fold Paralysis ◽

History Of

Cranial nerve palsies are potential but rare complications of spinal anaesthesia. Most of the literatures support upper cranial nerve palsies like VI, IV and III cranial nerve palsies. Intrathecal hypotension resulting in tractional injury of the cranial nerves is the likely mechanism of injury. As on date, some cases of unilateral vocal fold paralysis and very little bilateral vocal fold paralysis have been described in case reports. We have described a patient who developed hoarseness and dysphagia 7 days after receiving spinal anaesthesia for fixation of inter-trochanteric fracture femur. The patient was diagnosed with bilateral vocal fold paralysis. He was managed conservatively and exhibited complete spontaneous recovery as has been described in the previously reported cases. Any patient presenting with idiopathic vocal fold paralysis should be enquired about the history of spinal or epidural anaesthesia. If the history is affirmative, then it points towards transient intrathecal hypotension as a potential etiology of the cranial nerve palsy.

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