Heme Pocket Architecture in Human Serum Albumin: Regulation of O2Binding Affinity of a Prosthetic Heme Group by Site-Directed Mutagenesis

2008 ◽  
Vol 270 (1) ◽  
pp. 187-192 ◽  
Author(s):  
Teruyuki Komatsu ◽  
Akito Nakagawa ◽  
Eishun Tsuchida
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Heme Group ◽  
Heme Pocket ◽  
Prosthetic Heme Group

Dioxygenation of Human Serum Albumin Having a Prosthetic Heme Group in a Tailor-Made Heme Pocket

2004 ◽  
Vol 126 (44) ◽  
pp. 14304-14305 ◽  
Author(s):  
Teruyuki Komatsu ◽  
Naomi Ohmichi ◽  
Patricia A. Zunszain ◽  
Stephen Curry ◽  
Eishun Tsuchida
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Heme Group ◽  
Heme Pocket ◽  
Prosthetic Heme Group

Site-directed mutagenesis studies of human serum albumin define tryptophan at amino acid position 214 as the principal site for nitrosation

2002 ◽  
Vol 9 (1) ◽  
pp. 47-58 ◽  
Author(s):  
Krishna Harohalli ◽  
Charles E. Petersen ◽  
Chung-Eun Ha ◽  
Jimmy B. Feix ◽  
Nadhipuram V. Bhagavan
Keyword(s):  
Amino Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Amino Acid Position ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis

scholarly journals TOPOLOGY ANALYSIS OF DRUG BINDING SITES ON HUMAN SERUM ALBUMIN USING SITE-DIRECTED MUTAGENESIS

2000 ◽  
Vol 15 (supplement) ◽  
pp. 122-123
Author(s):  
Hiroshi WATANABE ◽  
Sumio TANASE ◽  
Keisuke NAKAJOU ◽  
Yasunori IWAO ◽  
Maki MITARAI ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Binding Sites ◽  
Drug Binding ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Topology Analysis ◽  
Drug Binding Sites

Probing the structure of the warfarin-binding site on human serum albumin using site-directed mutagenesis

2002 ◽  
Vol 47 (2) ◽  
pp. 116-125 ◽  
Author(s):  
Charles E. Petersen ◽  
Chung-Eun Ha ◽  
Stephen Curry ◽  
Nadhipuram V. Bhagavan
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Binding Site ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis

Chain Length-dependent Binding of Fatty Acid Anions to Human Serum Albumin Studied by Site-directed Mutagenesis

2006 ◽  
Vol 363 (3) ◽  
pp. 702-712 ◽  
Author(s):  
Ulrich Kragh-Hansen ◽  
Hiroshi Watanabe ◽  
Keisuke Nakajou ◽  
Yasunori Iwao ◽  
Masaki Otagiri
Keyword(s):  
Fatty Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Chain Length ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis

The role of an amino acid triad at the entrance of the heme pocket in human serum albumin for O2 and CO binding to iron protoporphyrin IX

2009 ◽  
Vol 7 (18) ◽  
pp. 3836 ◽  
Author(s):  
Teruyuki Komatsu ◽  
Akito Nakagawa ◽  
Stephen Curry ◽  
Eishun Tsuchida ◽  
Kenichi Murata ◽  
...  
Keyword(s):  
Amino Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Protoporphyrin Ix ◽  
Heme Pocket ◽  
Iron Protoporphyrin
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