Conditional deletion of mTOR discloses its essential role in early B‐cell development

2021 ◽  
Author(s):  
Shuling Zhang ◽  
Wendy Dubois ◽  
Xingmin Feng ◽  
Joe T. Nguyen ◽  
Neal S. Young ◽  
...  
Keyword(s):  
B Cell ◽  
Essential Role ◽  
Cell Development ◽  
B Cell Development ◽  
Conditional Deletion

scholarly journals COX-1–derived thromboxane A2 plays an essential role in early B-cell development via regulation of JAK/STAT5 signaling in mouse

Blood ◽  
2014 ◽  
Vol 124 (10) ◽  
pp. 1610-1621 ◽  
Author(s):  
Qiong Yang ◽  
Maohua Shi ◽  
Yujun Shen ◽  
Yingjiao Cao ◽  
Shengkai Zuo ◽  
...  
Keyword(s):  
B Cell ◽  
Essential Role ◽  
Suppressive Effect ◽  
Cell Development ◽  
B Cell Development ◽  
Dose Aspirin ◽  
Key Points ◽  
Low Dose Aspirin ◽  
Cox 1

Key Points This study demonstrated an essential role of COX-1 in early B-cell development. Low-dose aspirin may have a potential suppressive effect on B-cell development in humans.

Brutonˈs tyrosine kinase-an integral protein of B cell development that also has an essential role in the innate immune system

2013 ◽  
Vol 95 (2) ◽  
pp. 243-250 ◽  
Author(s):  
Gabriela López-Herrera ◽  
Alexander Vargas-Hernández ◽  
Maria Edith González-Serrano ◽  
Laura Berrón-Ruiz ◽  
Juan Carlos Rodríguez-Alba ◽  
...  
Keyword(s):  
Immune System ◽  
Tyrosine Kinase ◽  
B Cell ◽  
Innate Immune System ◽  
Essential Role ◽  
Cell Development ◽  
B Cell Development ◽  
Innate Immune ◽  
Integral Protein

scholarly journals Cutting Edge: Essential Role of Phospholipase C-γ2 in B Cell Development and Function

2000 ◽  
Vol 165 (4) ◽  
pp. 1738-1742 ◽  
Author(s):  
Ari Hashimoto ◽  
Kiyoshi Takeda ◽  
Muneo Inaba ◽  
Masayuki Sekimata ◽  
Tsuneyasu Kaisho ◽  
...  
Keyword(s):  
B Cell ◽  
Phospholipase C ◽  
Essential Role ◽  
Cell Development ◽  
B Cell Development ◽  
Cutting Edge ◽  
And Function

scholarly journals An essential role for the Zn2+ transporter ZIP7 in B cell development

2019 ◽  
Vol 20 (3) ◽  
pp. 350-361 ◽  
Author(s):  
Consuelo Anzilotti ◽  
David J. Swan ◽  
Bertrand Boisson ◽  
Mukta Deobagkar-Lele ◽  
Catarina Oliveira ◽  
...  
Keyword(s):  
B Cell ◽  
Essential Role ◽  
Cell Development ◽  
B Cell Development

Essential role of Src-family protein tyrosine kinases in NF-κB activation during B cell development

10.1038/ni893 ◽  
2003 ◽  
Vol 4 (3) ◽  
pp. 274-279 ◽  
Author(s):  
Kaoru Saijo ◽  
Christian Schmedt ◽  
I-hsin Su ◽  
Hajime Karasuyama ◽  
Clifford A. Lowell ◽  
...  
Keyword(s):  
B Cell ◽  
Tyrosine Kinases ◽  
Essential Role ◽  
Cell Development ◽  
B Cell Development ◽  
Protein Tyrosine Kinases ◽  
Protein Tyrosine ◽  
Family Protein

scholarly journals Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism

2016 ◽  
Vol 197 (6) ◽  
pp. 2250-2260 ◽  
Author(s):  
Terri N. Iwata ◽  
Julita A. Ramírez ◽  
Mark Tsang ◽  
Heon Park ◽  
Daciana H. Margineantu ◽  
...  
Keyword(s):  
B Cell ◽  
Essential Role ◽  
Cell Development ◽  
B Cell Development

scholarly journals Conditional Deletion of Sost in MSC-Derived Lineages Identifies Specific Cell-Type Contributions to Bone Mass and B-Cell Development

2018 ◽  
Vol 33 (10) ◽  
pp. 1748-1759 ◽  
Author(s):  
Cristal S Yee ◽  
Jennifer O Manilay ◽  
Jiun C Chang ◽  
Nicholas R Hum ◽  
Deepa K Murugesh ◽  
...  
Keyword(s):  
Bone Mass ◽  
B Cell ◽  
Cell Development ◽  
B Cell Development ◽  
Specific Cell ◽  
Cell Type ◽  
Specific Cell Type ◽  
Conditional Deletion
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