Deep brain stimulation effect on freezing of gait

2008 ◽  
Vol 23 (S2) ◽  
pp. S489-S494 ◽  
Author(s):  
Murielle U. Ferraye ◽  
Bettina Debû ◽  
Pierre Pollak
2018 ◽  
Vol 129 (10) ◽  
pp. 2083-2088 ◽  
Author(s):  
Éric Parmentier ◽  
Victor De Pasqua ◽  
Kévin D'Ostilio ◽  
Frédérique Depierreux ◽  
Gaëtan Garraux ◽  
...  

2020 ◽  
pp. 105-108
Author(s):  
Mariana Moscovich

Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a safe and long-term effective treatment for medication-refractory dystonia. However, complications and side effects may occur. Freezing of gait (FOG) is a rare phenomenon in patients with dystonia, although very frequently this complication is observed in patients with Parkinson disease (PD). FOG can be disabling and may severely impair quality of life, even when episodic. This chapter reports on a case of a 49-year-old left-handed man presenting with FOG, impairment in balance, and walking difficulty. These issues emerged 3 years after successful bilateral GPi DBS for primary generalized dystonia.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Belén González-Herrero ◽  
Serge Jauma-Classen ◽  
Roser Gómez-Llopico ◽  
Gerard Plans ◽  
Matilde Calopa

Background. Treatment of freezing of gait (FOG) is always challenging because of its unpredictable nature and multifactorial physiopathology. Intestinal levodopa infusion has been proposed in recent years as a valuable option for its improvement. FOG in Parkinson’s disease (PD) can appear after deep brain stimulation in patients who never had gait symptoms. Objective. To study the effects of intestinal levodopa/carbidopa infusion in unresponsive-FOG that appears in PD patients treated with subthalamic nucleus deep brain stimulation. Methods. We retrospectively collected and analyzed demographic, clinical, and therapeutic data from five PD patients treated with subthalamic nucleus stimulation who developed unresponsive-FOG and received intestinal levodopa/carbidopa infusion as an alternative therapy. FOG was measured based on scores in item 14 of the Unified Parkinson’s Disease Rating Scale before and after intestinal levodopa infusion. Results. Administration of intestinal levodopa caused improvement of FOG in the “ON” state in four patients (80%) by 2 or more points in item 14 of the Unified Parkinson’s Disease Rating Scale. The improvement was maintained for at least 12 months. Conclusions. Intestinal levodopa infusion may be a valuable therapeutic option for unresponsive-FOG developed after subthalamic nucleus deep brain stimulation.


2020 ◽  
Vol 13 (5) ◽  
pp. 1320-1322 ◽  
Author(s):  
Matthew N. Petrucci ◽  
Raumin S. Neuville ◽  
M. Furqan Afzal ◽  
Anca Velisar ◽  
Chioma M. Anidi ◽  
...  

2021 ◽  
Vol 14 (6) ◽  
pp. 1664
Author(s):  
Daniel Lench ◽  
Madison Brooks ◽  
Revuelta Gonzalo

PLoS ONE ◽  
2020 ◽  
Vol 15 (4) ◽  
pp. e0231984 ◽  
Author(s):  
Johanna O’Day ◽  
Judy Syrkin-Nikolau ◽  
Chioma Anidi ◽  
Lukasz Kidzinski ◽  
Scott Delp ◽  
...  

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