S ‐Allylcysteine Inhibits PhIP/DSS‐Induced Colon Carcinogenesis through Mitigating Inflammation, Targeting Keap1, and Modulating Microbiota Composition in Mice

2020 ◽  
Vol 64 (23) ◽  
pp. 2000576
Author(s):  
Wei‐Sheng Lin ◽  
Ying‐Jang Lai ◽  
Nagabhushanam Kalyanam ◽  
Chi‐Tang Ho ◽  
Min‐Hsiung Pan
Keyword(s):  
Colon Carcinogenesis ◽  
Microbiota Composition ◽  
Inflammation Targeting

Inter-individual variation shapes the human microbiome

2019 ◽  
Vol 42 ◽  
Author(s):  
Emily F. Wissel ◽  
Leigh K. Smith
Keyword(s):  
Individual Differences ◽  
Individual Variation ◽  
Human Microbiome ◽  
Individual Variability ◽  
Microbiota Composition ◽  
Target Article ◽  
Microbiome Research

Abstract The target article suggests inter-individual variability is a weakness of microbiota-gut-brain (MGB) research, but we discuss why it is actually a strength. We comment on how accounting for individual differences can help researchers systematically understand the observed variance in microbiota composition, interpret null findings, and potentially improve the efficacy of therapeutic treatments in future clinical microbiome research.

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