scholarly journals Monte Carlo simulation of conical collimators for stereotactic radiosurgery with a 6 MV flattening‐filter‐free photon beam

2021 ◽  
Author(s):  
Marcelino Hermida‐López ◽  
David Sánchez‐Artuñedo ◽  
Miguel Rodríguez ◽  
Lorenzo Brualla
2017 ◽  
Vol 46 (9) ◽  
pp. 1407-1411 ◽  
Author(s):  
Arif Efendi M. ◽  
Amporn Funsian ◽  
Thawat Chittrakarn ◽  
Tripob Bhongsuwan

2017 ◽  
Vol 44 (10) ◽  
pp. 5378-5383 ◽  
Author(s):  
Immaculada Martínez-Rovira ◽  
Josep Puxeu-Vaqué ◽  
Yolanda Prezado

2009 ◽  
Vol 92 ◽  
pp. S57 ◽  
Author(s):  
M. Lind ◽  
T. Knöös ◽  
C. Ceberg ◽  
E. Wieslander ◽  
B. McClean ◽  
...  

2020 ◽  
Vol 10 (20) ◽  
pp. 7052
Author(s):  
James C. L. Chow

The aim of this study is to investigate the variations of depth dose enhancement (DDE) on different nanoparticle (NP) variables, when using the flattening-filter-free (FFF) photon beam in nanoparticle-enhanced radiotherapy. Monte Carlo simulation under a macroscopic approach was used to determine the DDE ratio (DDER) with variables of NP material (gold (Au) and iron (III) oxide (Fe2O3)), NP concentration (3–40 mg/mL) and photon beam (10 MV flattening-filter (FF) and 10 MV FFF). It is found that Au NPs had a higher DDER than Fe2O3 NPs, when the depths were shallower than 6 and 8 cm for the 10 MV FF and 10 MV FFF photon beams, respectively. However, in a deeper depth range of 10–20 cm, DDER for the Au NPs was lower than Fe2O3 NPs mainly due to the beam attenuation and photon energy distribution. It is concluded that DDER for the Au NPs and Fe2O3 NPs decreased with an increase of depth in the range of 10–20 cm, with rate of decrease depending on the NP material, NP concentration and the use of FF in the photon beam.


2006 ◽  
Vol 33 (6Part12) ◽  
pp. 2123-2123 ◽  
Author(s):  
U Titt ◽  
F Poenisch ◽  
S Kry ◽  
X Zhu ◽  
R Mohan ◽  
...  

Nanomaterials ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 920 ◽  
Author(s):  
Aniza Abdulle ◽  
James C. L. Chow

Our team evaluated contrast enhancement for portal imaging using Monte Carlo simulation in nanoparticle-enhanced radiotherapy. Dependencies of percentage contrast enhancement on flattening-filter (FF) and flattening-filter-free (FFF) photon beams were determined by varying the nanoparticle material (gold, platinum, iodine, silver, iron oxide), nanoparticle concentration (3–40 mg/mL) and photon beam energy (6 and 10 MV). Phase-space files and energy spectra of the 6 MV FF, 6 MV FFF, 10 MV FF and 10 MV FFF photon beams were generated based on a Varian TrueBeam linear accelerator. We found that gold and platinum nanoparticles (NP) produced the highest contrast enhancement for portal imaging, compared to other NP with lower atomic numbers. The maximum percentage contrast enhancements for the gold and platinum NP were 18.9% and 18.5% with a concentration equal to 40 mg/mL. The contrast enhancement was also found to increase with the nanoparticle concentration. The maximum rate of increase of contrast enhancement for the gold NP was equal to 0.29%/mg/mL. Using the 6 MV photon beams, the maximum contrast enhancements for the gold NP were 79% (FF) and 78% (FFF) higher than those using the 10 MV beams. For the FFF beams, the maximum contrast enhancements for the gold NP were 53.6% (6 MV) and 53.8% (10 MV) higher than those using the FF beams. It is concluded that contrast enhancement for portal imaging can be increased when a higher atomic number of NP, higher nanoparticle concentration, lower photon beam energy and no flattening filter of photon beam are used in nanoparticle-enhanced radiotherapy.


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