A tetrodotoxin- and Mn2+-insensitive Na+ current in Duchenne muscular dystrophy

1990 ◽  
Vol 13 (10) ◽  
pp. 939-948 ◽  
Author(s):  
Ghassan Bkaily ◽  
Ga�tan Jasmin ◽  
Constantin Tautu ◽  
Libuse Prochek ◽  
Tatsuo Yamamoto ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Na Current

Reduced Na+ current in Purkinje fibers explains cardiac conduction defects and arrhythmias in Duchenne muscular dystrophy

2020 ◽  
Vol 318 (6) ◽  
pp. H1436-H1440
Author(s):  
Janine Ebner ◽  
Pavel Uhrin ◽  
Petra L. Szabo ◽  
Attila Kiss ◽  
Bruno K. Podesser ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Cardiac Conduction ◽  
Na Current ◽  
Purkinje Fibers ◽  
Cardiac Purkinje Fibers ◽  
Current Densities ◽  
Ventricular Conduction

Dystrophic cardiac Purkinje fibers have abnormally reduced Na+ current densities. This explains impaired ventricular conduction in the dystrophic heart.

Growth and psychomotor development of patients with Duchenne Muscular Dystrophy

2012 ◽  
Vol 43 (02) ◽  
Author(s):  
E Sarrazin ◽  
M von der Hagen ◽  
U Schara ◽  
K von Au ◽  
A Kaindl
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Psychomotor Development

The Six-Minute Walk Test (6MWT) as Endpoint in Duchenne Muscular Dystrophy (DMD) Clinical Studies

2016 ◽  
Vol 47 (S 01) ◽  
Author(s):  
S.-M. Park ◽  
C. McDonald ◽  
H. Sweeney ◽  
X. Luo ◽  
G. Elfring ◽  
...  
Keyword(s):  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Clinical Studies ◽  
Walk Test ◽  
Six Minute Walk Test ◽  
Minute Walk

Ataluren: Clinical Trial Results in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)

2016 ◽  
Vol 47 (S 01) ◽  
Author(s):  
U. Schara ◽  
C. McDonald ◽  
K. Bushby ◽  
M. Tulinius ◽  
R. Finkel ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Nonsense Mutation ◽  
Clinical Trial Results
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