Micelles formed by self-assembling of low molecular weight phosphorylcholine-containing poly(L-lactide)

2011 ◽  
Vol 23 (10) ◽  
pp. 1357-1361 ◽  
Author(s):  
Yuanwei Chen ◽  
Jing Chen ◽  
Yanjun Liu ◽  
Xianglin Luo ◽  
Suming Li
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight ◽  
Self Assembling

Pteridine derivatives: novel low-molecular-weight organogelators and their piezofluorochromism

2020 ◽  
Vol 44 (8) ◽  
pp. 3382-3391
Author(s):  
Shenzheng Xu ◽  
Xiaoyu Jia ◽  
Jiaxin Lu ◽  
Lianyou Zheng ◽  
Kuo Lv ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Organic Solvents ◽  
Low Molecular Weight ◽  
Self Assembling ◽  
Conjugated Compounds ◽  
Low Molecular Weight Organogelators ◽  
Pteridine Derivatives

Here, π-conjugated compounds based on pteridine derivatives were synthesized and their self-assembling behaviors in a variety of organic solvents and piezofluorochromism were studied.

scholarly journals A self-assembling polycationic nanocarrier that exhibits exceptional gene transfection efficiency

RSC Advances ◽  
2015 ◽  
Vol 5 (111) ◽  
pp. 91619-91632 ◽  
Author(s):  
Kishor Sarkar ◽  
Sai Rama Krishna Meka ◽  
Giridhar Madras ◽  
Kaushik Chatterjee
Keyword(s):  
Molecular Weight ◽  
Transfection Efficiency ◽  
Gene Transfection ◽  
Gene Carrier ◽  
Low Molecular Weight ◽  
High Transfection Efficiency ◽  
Self Assembling

A novel polycationic gene carrier was prepared by conjugation of low molecular weight polyethyleneimine with gelatin through 4-bromonaphthaleic anhydride with exceptionally high transfection efficiency.

scholarly journals Synthesis and characterization of pH responsive D-glucosamine based molecular gelators

2014 ◽  
Vol 10 ◽  
pp. 3111-3121 ◽  
Author(s):  
Navneet Goyal ◽  
Hari P R Mangunuru ◽  
Bargav Parikh ◽  
Sonu Shrestha ◽  
Guijun Wang
Keyword(s):  
Molecular Weight ◽  
Building Blocks ◽  
Negative Influence ◽  
Low Molecular Weight ◽  
Ph Responsive ◽  
Triggered Release ◽  
Self Assembling ◽  
Potential Applications ◽  
Low Molecular Weight Gelators ◽  
Neutral Conditions

Small molecular gelators are a class of compounds with potential applications for soft biomaterials. Low molecular weight hydrogelators are especially useful for exploring biomedical applications. Previously, we found that 4,6-O-benzylidene acetal protected D-glucose and D-glucosamine are well-suited as building blocks for the construction of low molecular weight gelators. To better understand the scope of D-glucosamine derivatives as gelators, we synthesized and screened a novel class of N-acetylglucosamine derivatives with a p-methoxybenzylidene acetal protective group. This modification did not exert a negative influence on the gelation. On the contrary, it actually enhanced the gelation tendency for many derivatives. The introduction of the additional methoxy group on the phenyl ring led to low molecular weight gelators with a higher pH responsiveness. The resulting gels were stable at neutral pH values but degraded in an acidic environment. The release profiles of naproxen from the pH responsive gels were also analyzed under acidic and neutral conditions. Our findings are useful for the design of novel triggered release self-assembling systems and can provide an insight into the influence of the the structure on gelation.

scholarly journals Development of an Amino Sugar-Based Supramolecular Hydrogelator with Reduction Responsiveness

2021 ◽  
Author(s):  
Sayuri L. Higashi ◽  
Masato Ikeda
Keyword(s):  
Molecular Weight ◽  
Molecular Design ◽  
Soft Materials ◽  
Amino Sugar ◽  
Low Molecular Weight ◽  
Stimuli Responsive ◽  
Supramolecular Hydrogel ◽  
Self Assembling ◽  
Hydrogel Formation

Stimuli-responsive supramolecular hydrogels are a newly emerging class of aqueous soft materials with a wide variety of bioapplications. Here we report a reduction-responsive supramolecular hydrogel constructed from a markedly simple low-molecular-weight hydrogelator, which is developed on the basis of modular molecular design containing a hydrophilic amino sugar and a reduction-responsive nitrophenyl group. The hydrogel formation ability differs significantly between glucosamine- and galactosamine-based self-assembling molecules, which are epimers at the C4 position, and only the glucosamine-based derivative can act as a hydrogelator.

Functional organogels from lipophilic L-glutamide derivative immobilized on cyclotriphosphazene core

2006 ◽  
Vol 21 (5) ◽  
pp. 1274-1278 ◽  
Author(s):  
Tomohiro Shirosaki ◽  
Saleh Chowdhury ◽  
Makoto Takafuji ◽  
Dzhamil Alekperov ◽  
Galina Popova ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Molecular Weight ◽  
Transmission Electron Microscopy ◽  
Transmission Electron Microscopy Observation ◽  
Low Molecular Weight ◽  
Microscopy Observation ◽  
The Core ◽  
Self Assembling ◽  
Transmission Electron ◽  
Gelation Test

A novel cyclotriphosphazene-based low-molecular weight organogelator was prepared by immobilization of six dialkylated L-glutamide derivatives on a cyclotriphosphazene core, and its ability as a self-assembling organogelator was investigated. The organogelator exhibited enhanced gelation ability and chirality, and thixotropic property for self-restoring to a gel state; this was compared to the corresponding L-glutamide-derived organogelator without the core. The gelation test, transmission electron microscopy observation, and circular dichroism (CD) spectral study showed that the gelation and aggregation ability were enhanced by immobilization onto the cyclotriphosphazene core. Gels in chloroform and cyclohexane-ethanol (95:5) mixture showed an unusual thixotropic property.

Studies on organogelation of self assembling bis urea type low molecular weight molecules

2014 ◽  
Vol 71 (2) ◽  
pp. 372-379 ◽  
Author(s):  
B. Sravan ◽  
K. Kamalakar ◽  
M. S. L. Karuna ◽  
Aruna Palanisamy
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight ◽  
Self Assembling

Cooperative binding and self-assembling behavior of cationic low molecular-weight dendrons with RNA molecules

2006 ◽  
Vol 4 (3) ◽  
pp. 581 ◽  
Author(s):  
Jiehua Zhou ◽  
Jiangyu Wu ◽  
Xiaoxuan Liu ◽  
Fanqi Qu ◽  
Mu Xiao ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Cooperative Binding ◽  
Low Molecular Weight ◽  
Rna Molecules ◽  
Self Assembling
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