scholarly journals Predictors of adaptive functioning and psychosocial adjustment in children with pediatric brain tumor: A report from the brain radiation investigative study consortium

2014 ◽  
Vol 62 (3) ◽  
pp. 509-516 ◽  
Author(s):  
Kristen E. Robinson ◽  
Kelly R. Wolfe ◽  
Keith O. Yeates ◽  
E. Mark Mahone ◽  
Kim M. Cecil ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Psychosocial Adjustment ◽  
Adaptive Functioning ◽  
Pediatric Brain Tumor ◽  
Brain Radiation ◽  
Pediatric Brain ◽  
The Brain

Predicting changes in adaptive functioning and behavioral adjustment following treatment for a pediatric brain tumor: A report from the Brain Radiation Investigative Study Consortium

2017 ◽  
Vol 27 (1) ◽  
pp. 178-186 ◽  
Author(s):  
Kristen R. Hoskinson ◽  
Kelly R. Wolfe ◽  
Keith Owen Yeates ◽  
E. Mark Mahone ◽  
Kim M. Cecil ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Adaptive Functioning ◽  
Pediatric Brain Tumor ◽  
Behavioral Adjustment ◽  
Brain Radiation ◽  
Pediatric Brain ◽  
The Brain

scholarly journals Improved neuropsychological outcomes following proton therapy relative to X-ray therapy for pediatric brain tumor patients

2019 ◽  
Vol 21 (7) ◽  
pp. 934-943 ◽  
Author(s):  
Jeffrey P Gross ◽  
Stephanie Powell ◽  
Frank Zelko ◽  
William Hartsell ◽  
Stewart Goldman ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Processing Speed ◽  
Adaptive Functioning ◽  
Pediatric Brain Tumor ◽  
Neuropsychological Evaluation ◽  
Tumor Patients ◽  
X Ray ◽  
Neuropsychological Outcomes ◽  
Pediatric Brain

AbstractBackgroundSurvivors of pediatric brain tumors are at risk for impaired development in multiple neuropsychological domains. The purpose of this study was to compare neuropsychological outcomes of pediatric brain tumor patients who underwent X-ray radiotherapy (XRT) versus proton radiotherapy (PRT).MethodsPediatric patients who underwent either XRT or PRT and received posttreatment age-appropriate neuropsychological evaluation—including measures of intelligence (IQ), attention, memory, visuographic skills, academic skills, and parent-reported adaptive functioning—were identified. Multivariate analyses were performed to assess differences in neuropsychological outcomes and included tests for interaction between treatment cohort and follow-up time.ResultsBetween 1998 and 2017, 125 patients with tumors located in the supratentorial (17.6%), midline (28.8%), or posterior fossa (53.6%) compartments received radiation and had posttreatment neuropsychological evaluation. Median age at treatment was 7.4 years. The PRT patient cohort had higher estimated SES and shorter median time from radiotherapy completion to last neuropsychological evaluation (6.7 vs 2.6 y, P < 0.001). On multivariable analysis, PRT was associated with higher full-scale IQ (β = 10.6, P = 0.048) and processing speed (β = 14.4, P = 0.007) relative to XRT, with trend toward higher verbal IQ (β = 9.9, P = 0.06) and general adaptive functioning (β = 11.4, P = 0.07). Planned sensitivity analyses truncating follow-up interval in the XRT cohort re-demonstrated higher verbal IQ (P = 0.01) and IQ (P = 0.04) following PRT, with trend toward improved processing speed (P = 0.09).ConclusionsPRT is associated with favorable outcomes for intelligence and processing speed. Combined with other strategies for treatment de-intensification, PRT may further reduce neuropsychological morbidity of brain tumor treatment.

scholarly journals Executive Function and Psychosocial Adjustment in Adolescent Survivors of Pediatric Brain Tumor

2021 ◽  
pp. 1-20
Author(s):  
A. Puhr ◽  
E. Ruud ◽  
V. Anderson ◽  
B.J. Due-Tønnessen ◽  
A.B. Skarbø ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Executive Function ◽  
Psychosocial Adjustment ◽  
Pediatric Brain Tumor ◽  
Pediatric Brain

Cognitive Predictors of Adaptive Functioning Vary According to Pediatric Brain Tumor Location

2008 ◽  
Vol 33 (4) ◽  
pp. 505-520 ◽  
Author(s):  
Aimilia Papazoglou ◽  
Tricia Z. King ◽  
Robin D. Morris ◽  
Nicolas S. Krawiecki
Keyword(s):  
Brain Tumor ◽  
Adaptive Functioning ◽  
Pediatric Brain Tumor ◽  
Tumor Location ◽  
Cognitive Predictors ◽  
Pediatric Brain

scholarly journals NC-10 * TRAINING THE BRAIN TO REPAIR ITSELF: AN EXERCISE TRIAL IN PEDIATRIC BRAIN TUMOR SURVIVORS

2014 ◽  
Vol 16 (suppl 5) ◽  
pp. v136-v136 ◽  
Author(s):  
D. Mabbott ◽  
L. Riggs ◽  
J. Piscione ◽  
S. Laughlin ◽  
T. Cunningham ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Pediatric Brain Tumor ◽  
Pediatric Brain ◽  
The Brain

scholarly journals Neurocognitive and Psychosocial Outcomes in Pediatric Brain Tumor Survivors

2018 ◽  
Vol 5 (3) ◽  
pp. 73 ◽  
Author(s):  
Peter Stavinoha ◽  
Martha Askins ◽  
Stephanie Powell ◽  
Natasha Pillay Smiley ◽  
Rhonda Robert
Keyword(s):  
Brain Tumor ◽  
Psychosocial Adjustment ◽  
Late Effects ◽  
Intellectual Development ◽  
Pediatric Brain Tumor ◽  
Psychosocial Outcomes ◽  
Psychosocial Effects ◽  
Ongoing Research ◽  
Employment Rates ◽  
Pediatric Brain

The late neurocognitive and psychosocial effects of treatment for pediatric brain tumor (PBT) represent important areas of clinical focus and ongoing research. Neurocognitive sequelae and associated problems with learning and socioemotional development negatively impact PBT survivors’ overall health-related quality of life, educational attainment and employment rates. Multiple factors including tumor features and associated complications, treatment methods, individual protective and vulnerability factors and accessibility of environmental supports contribute to the neurocognitive and psychosocial outcomes in PBT survivors. Declines in overall measured intelligence are common and may persist years after treatment. Core deficits in attention, processing speed and working memory are postulated to underlie problems with overall intellectual development, academic achievement and career attainment. Additionally, psychological problems after PBT can include depression, anxiety and psychosocial adjustment issues. Several intervention paradigms are briefly described, though to date research on innovative, specific and effective interventions for neurocognitive late effects is still in its early stages. This article reviews the existing research for understanding PBT late effects and highlights the need for innovative research to enhance neurocognitive and psychosocial outcomes in PBT survivors.

scholarly journals Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status

2019 ◽  
Vol 66 (9) ◽  
Author(s):  
Kimberly P. Raghubar ◽  
Jessica Orobio ◽  
M. Douglas Ris ◽  
Andrew M. Heitzer ◽  
Alexandra Roth ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Brain Tumor ◽  
Adaptive Functioning ◽  
Pediatric Brain Tumor ◽  
Pediatric Brain
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