Improving outcome of acute lymphoblastic leukemia with a simplified protocol: report from a tertiary care center in north India

2016 ◽  
Vol 64 (4) ◽  
pp. e26281 ◽  
Author(s):  
Amita Trehan ◽  
Deepak Bansal ◽  
Neelam Varma ◽  
Ajay Vora
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
North India ◽  
Tertiary Care Center

Childhood T-lineage acute lymphoblastic leukemia: Management and outcome at a tertiary care center in North India

2011 ◽  
Vol 48 (10) ◽  
pp. 785-790 ◽  
Author(s):  
L. S. Arya ◽  
K. S. Padmanjali ◽  
S. Sazawal ◽  
R. Saxena ◽  
M. Bhargava ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
North India ◽  
Tertiary Care Center

Childhood acute lymphoblastic leukemia managed in tertiary care center in a developing country

2003 ◽  
Vol 41 (1) ◽  
pp. 83-84 ◽  
Author(s):  
Ibrahim A. Dabbous ◽  
Hassan Dbouk ◽  
Abla-Mehio Sibai ◽  
Lama Bahlawan
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Developing Country ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
Childhood Acute Lymphoblastic Leukemia ◽  
Tertiary Care Center

scholarly journals Acute Lymphoblastic Leukemia in Adults - an Analysis of 51 Cases from a Tertiary Care Center in Pakistan

2016 ◽  
Vol 17 (4) ◽  
pp. 2307-2309 ◽  
Author(s):  
Sadia Sultan ◽  
Syed Mohammed Irfan ◽  
Saira Parveen ◽  
Sanober Mustafa
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center

Thrombosis in Children with Acute Lymphoblastic Leukemia Treated at a Tertiary Care Center in Lebanon: Revisiting the Role of Predictive Models

2011 ◽  
Vol 28 (8) ◽  
pp. 676-681 ◽  
Author(s):  
Carol Al-Aridi ◽  
Miguel R. Abboud ◽  
Raya Saab ◽  
Dalia Eid ◽  
Sima Jeha ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Predictive Models ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center

scholarly journals Isolated CNS Relapse in Acute Lymphoblastic Leukemia (ALL): An Experience from a Tertiary Care Center

2021 ◽  
Author(s):  
Manvir Singh Tevatia ◽  
Isha Sharma ◽  
Toyaja Jadhav ◽  
Venkatesan Somasundaram ◽  
Sanjeevan Sharma
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Presenting Symptoms ◽  
Cns Relapse ◽  
Definitive Therapy ◽  
The Central Nervous System ◽  
Systemic Relapse

Abstract Aims and Objectives In this study the various parameters of acute lymphoblastic leukemia (ALL), including the clinical features, peripheral blood and bone marrow (BM) findings, immunophenotypic and cytogenetic details in ALL cases who had isolated relapse involving the central nervous system (CNS), were studied. Patients/Materials and Methods Duration of the study is from 2015 to 2019 in which 5 ALL cases were presented to this tertiary care center. The presenting symptoms varied from headache, fever, and distension of abdomen. These cases were either on therapy or post completion of chemotherapy. The diagnosis of CNS relapse followed after the examination of cerebrospinal fluid (CSF). Patients also underwent BM examination to rule out systemic relapse. Results Age of patients ranged from 7 months to 42 years. There were three female patients. Two patients had isolated CNS relapse 3.5 years after completing therapy and succumbed to their illness. Two patients had t(9;22) while one patient had t(1;14) cytogenetic abnormality at diagnosis. One patient was diagnosed as T-ALL. Treatment offered was German Multicentre ALL protocol for induction along with 10 cycles of maintenance. Conclusion The most common hematolymphoid malignancy in children namely ALL accounts for 75% of childhood leukemias. Complete remission rates reach up to 70 to 80%. CNS involvement is known to occur in these cases. CNS relapse may occur alone or with systemic relapse. Advances in therapeutic protocols along with CNS prophylaxis have drastically brought down the rates of CNS relapse. It is essential to maintain a high degree of suspicion so that these cases of isolated CNS relapse can be identified at the earliest and definitive therapy can be offered.

scholarly journals Aberrant myeloid antigen co-expression is correlated with high percentages of CD34-positive cells among blasts of acute lymphoblastic leukemia patients: an Indian tertiary care center perspective

2014 ◽  
Vol 49 (4) ◽  
pp. 241 ◽  
Author(s):  
Rahul Kumar Sharma ◽  
Abhishek Purohit ◽  
Venkatesan Somasundaram ◽  
Pravas Chandra Mishra ◽  
Mrinalini Kotru ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center
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