scholarly journals Exploring the frontier of cardiovascular pharmacotherapy

2021 ◽  
Vol 41 (12) ◽  
pp. 968-969
Author(s):  
William L. Baker ◽  
Cynthia A. Jackevicius
2005 ◽  
Vol 98 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Angelo A. Izzo ◽  
Giulia Di Carlo ◽  
Francesca Borrelli ◽  
Edzard Ernst

2019 ◽  
Vol 15 (2) ◽  
pp. 77-81
Author(s):  
Karel Koubský ◽  
Jan Janoušek ◽  
Václav Chaloupecký

2005 ◽  
Vol 40 (11) ◽  
pp. 954-962
Author(s):  
James M. Backes ◽  
Patricia A. Howard

This continuing feature will update readers on recent developments in cardiovascular pharmacotherapy. Cardiovascular disease remains the number one killer in the US, and more clinical outcome trials have been conducted in cardiology than in any other field of medicine. Given this rapidly expanding knowledge base, pharmacists can have a significant impact on prevention and treatment — if they keep current with developments in drug therapy.


2019 ◽  
Vol 6 (2) ◽  
pp. 104-114 ◽  
Author(s):  
Ivana Hollan ◽  
Nicoletta Ronda ◽  
Patrick Dessein ◽  
Stefan Agewall ◽  
George Karpouzas ◽  
...  

Abstract Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity, partly due to alterations in lipoprotein quantity, quality and cell cholesterol trafficking. Although cardiovascular disease significantly contributes to mortality excess in RA, cardiovascular prevention has been largely insufficient. Because of limited evidence, optimal strategies for lipid management (LM) in RA have not been determined yet, and recommendations are largely based on expert opinions. In this position paper, we describe abnormalities in lipid metabolism and introduce a new algorithm for estimation of cardiovascular risk (CVR) and LM in RA. The algorithm stratifies patients according to RA-related factors impacting CVR (such as RA activity and severity and medication). We propose strategies for monitoring of lipid parameters and treatment of dyslipidaemia in RA (including lifestyle, statins and other lipid-modifying therapies, and disease modifying antirheumatic drugs). These opinion-based recommendations are meant to facilitate LM in RA until more evidence is available.


2002 ◽  
Vol 37 (5) ◽  
pp. 474-482
Author(s):  
Patricia A. Howard

This continuing feature will update readers on recent developments in cardiovascular pharmacotherapy. Cardiovascular disease remains the number one killer in the US, and more clinical outcome trials have been conducted in cardiology than in any other field of medicine. Given this rapidly expanding knowledge base, pharmacists can have a significant impact on the prevention and treatment of cardiovascular disease—if they keep current with developments in drug therapy.


2019 ◽  
Vol 6 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Heinz Drexel ◽  
Giuseppe M C Rosano ◽  
Basil S Lewis ◽  
Kurt Huber ◽  
Alexander Vonbank ◽  
...  

Abstract Randomized clinical trials (RCTs) are important and the Gold Standard for drugs in modern cardiovascular (CV) therapy. The cornerstone of RCTs is the recording of hard clinical endpoints instead of surrogates. It is important to select an appropriate endpoint. Efficacy endpoints must be clinically relevant and can be hierarchically divided. A very interesting innovation in endpoint acquisition is the total event paradigm.


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