Parallel high-throughput accurate mass measurement using a nine-channel multiplexed electrospray liquid chromatography ultraviolet time-of-flight mass spectrometry system

2003 ◽  
Vol 17 (13) ◽  
pp. 1425-1432 ◽  
Author(s):  
Liling Fang ◽  
Michael Demee ◽  
Jason Cournoyer ◽  
Teresa Sierra ◽  
Connie Young ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
High Throughput ◽  
Mass Measurement ◽  
Time Of Flight ◽  
Accurate Mass Measurement ◽  
Accurate Mass ◽  
Flight Mass Spectrometry ◽  
Mass Spectrometry System

Identification of an unknown?-agonist in feed by liquid chromatography/bioassay/quadrupole time-of-flight tandem mass spectrometry with accurate mass measurement

2003 ◽  
Vol 17 (14) ◽  
pp. 1633-1641 ◽  
Author(s):  
M. W. F. Nielen ◽  
C. T. Elliott ◽  
S. A. Boyd ◽  
D. Courtheyn ◽  
M. L. Essers ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Mass Measurement ◽  
Time Of Flight ◽  
Accurate Mass Measurement ◽  
Accurate Mass ◽  
Tandem Mass

Accurate mass measurement of DNA oligonucleotide ions using high-resolution time-of-flight mass spectrometry

2002 ◽  
Vol 37 (4) ◽  
pp. 357-371 ◽  
Author(s):  
John M. Koomen ◽  
William K. Russell ◽  
Shane E. Tichy ◽  
David H. Russell
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Mass Measurement ◽  
Time Of Flight ◽  
Accurate Mass Measurement ◽  
Accurate Mass ◽  
Resolution Time ◽  
Flight Mass Spectrometry

Characterization of DON and DON-3-β-D-glucopyranoside through accurate mass measurement by quadrupole-time-of-flight mass spectrometry

2013 ◽  
Vol 93 (1) ◽  
pp. 61-74 ◽  
Author(s):  
Vildes Maria Scussel ◽  
Mervi Rokka ◽  
Aldo Rizzo ◽  
Marika Jestoi ◽  
Kimmo Peltonen
Keyword(s):  
Mass Spectrometry ◽  
Mass Measurement ◽  
Time Of Flight ◽  
Accurate Mass Measurement ◽  
Accurate Mass ◽  
Flight Mass Spectrometry

A new potential biomarker for 1-testosterone misuse in human urine by liquid chromatography quadruple time-of-flight mass spectrometry

2015 ◽  
Vol 7 (11) ◽  
pp. 4486-4492 ◽  
Author(s):  
Yang Liu ◽  
Jianghai Lu ◽  
Sheng Yang ◽  
Youxuan Xu ◽  
Xiaobing Wang
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Human Urine ◽  
Mass Measurement ◽  
Time Of Flight ◽  
Accurate Mass ◽  
Metabolic Profiles ◽  
Flight Mass Spectrometry ◽  
Potential Biomarker ◽  
Full Scan

In this study, 1-testosterone urinary metabolic profiles were investigated by liquid chromatography quadruple time-of-flight mass spectrometry (LC-QTOF-MS) using full scan and targeted MS/MS techniques with accurate mass measurement.

The Use of Accurate Mass Measurement by Orthogonal Time-of-Flight Mass Spectrometry in Pharmaceuticals Research

2000 ◽  
Vol 6 (2) ◽  
pp. 219-224 ◽  
Author(s):  
Frank Cottee ◽  
Neville Haskins ◽  
Duncan Bryant ◽  
Christine Eckers ◽  
Soraya Monté
Keyword(s):  
Mass Spectrometry ◽  
Mass Measurement ◽  
Time Of Flight ◽  
Accurate Mass Measurement ◽  
Accurate Mass ◽  
Mass Spectrometers ◽  
Additional Information ◽  
Flight Mass Spectrometry ◽  
Founding Editor ◽  
Major Application

Allan Maccoll was the founding editor of Organic Mass Spectrometry, the first journal dedicated to the application of mass spectrometry to the analysis of organic structures. Many papers in OMS described the elucidation of structures from natural and synthetic sources. This is still a major application of mass spectrometry today, especially in those fine chemical industries such as Pharmaceuticals which depend on the discovery and development of organic compounds for a variety of applications. In this paper we describe the advances we have made in the last few years, especially utilising time-of-flight (ToF) mass spectrometers, to use accurate mass measurement to determine the structures of minor components contained within drug substance and degraded samples. The additional information obtained from accurate mass measurement is shown to be critical in assigning a particular structure in a number of examples.

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