Citric-Acid-Catalyzed Green and Sustainable Synthesis of Novel Functionalized Pyrano[2, 3-e
]pyrimidin- and Pyrano[2, 3-d
]pyrazol-amines in Water via One-Pot Multicomponent Approaches
Pyridines and fused pyridines are accessible by a combination of a Lewis acid-catalyzed multicomponent reaction and aromatization involving loss of a 2-furylmethyl chain.
Lewis acid-mediated one-pot tandem cyclization of o-QMs with arylsulfonyl hydrazides was described for the first time and the corresponding 3-sulfonylbenzofuran products were obtained in moderate to good yields.