Impairment of the mitochondrial oxidative phosphorylation system and oxidative stress in liver of crucian carp (Carassius auratusL.) exposed to microcystins

2011 ◽  
Vol 29 (1) ◽  
pp. 30-39 ◽  
Author(s):  
Yanyan Zhao ◽  
Ping Xie ◽  
Huihui Fan ◽  
Sujuan Zhao
Keyword(s):  
Oxidative Stress ◽  
Oxidative Phosphorylation ◽  
Crucian Carp ◽  
Mitochondrial Oxidative Phosphorylation ◽  
Oxidative Phosphorylation System ◽  
And Oxidative Stress

The effect of maternal low-protein diet on the heart of adult offspring: role of mitochondria and oxidative stress

2014 ◽  
Vol 39 (8) ◽  
pp. 880-887 ◽  
Author(s):  
Luciana Nascimento ◽  
Cristiane M. Freitas ◽  
Reginaldo Silva-Filho ◽  
Ana Catarina R. Leite ◽  
Alessandra B. Silva ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Phosphorylation ◽  
Protein Restriction ◽  
Protein Diet ◽  
Male Rats ◽  
Low Protein Diet ◽  
Adult Offspring ◽  
Mitochondrial Oxidative Phosphorylation ◽  
Low Protein ◽  
And Oxidative Stress

Protein restriction during perinatal and early postnatal development is associated with a greater incidence of disease in the adult, such arterial hypertension. The aim in the present study was to investigate the effect of maternal low-protein diet on mitochondrial oxidative phosphorylation capacity, mitochondrial reactive oxygen species (ROS) formation, antioxidant levels (enzymatic and nonenzymatic), and oxidative stress levels on the heart of the adult offspring. Pregnant Wistar rats received either 17% casein (normal protein, NP) or 8% casein (low protein, LP) throughout pregnancy and lactation. After weaning male progeny of these NP or LP fed rats, females were maintained on commercial chow (Labina-Purina). At 100 days post-birth, the male rats were sacrificed and heart tissue was harvested and stored at −80 °C. Our results show that restricting protein consumption in pregnant females induced decreased mitochondrial oxidative phosphorylation capacity (51% reduction in ADP-stimulated oxygen consumption and 49.5% reduction in respiratory control ratio) in their progeny when compared with NP group. In addition, maternal low-protein diet induced a significant decrease in enzymatic antioxidant capacity (37.8% decrease in superoxide dismutase activity; 42% decrease in catalase activity; 44.8% decrease in glutathione-S-transferase activity; 47.9% decrease in glutathione reductase; 25.7% decrease in glucose-6 phosphate dehydrogenase) and glutathione level (34.8% decrease) when compared with control. From these findings, we hypothesize that an increased production of ROS and decrease in antioxidant activity levels induced by protein restriction during development could potentiate the progression of metabolic and cardiac diseases in adulthood.

scholarly journals 175 The effects of tbq on cardiac intracellular atp levels; role of oxidative phosphorylation and oxidative stress

Heart ◽  
2017 ◽  
Vol 103 (Suppl 5) ◽  
pp. A122.1-A122
Author(s):  
Natasha Hadgraft ◽  
David Greensmith ◽  
Gina Galli ◽  
Louise Miller
Keyword(s):  
Oxidative Stress ◽  
Oxidative Phosphorylation ◽  
Intracellular Atp ◽  
Atp Levels ◽  
And Oxidative Stress

scholarly journals ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferation by oxidation of NADH in mitochondrial oxidative phosphorylation system

Theranostics ◽  
2020 ◽  
Vol 10 (26) ◽  
pp. 12044-12059
Author(s):  
Xiaoxin Zhang ◽  
Yingchun Dong ◽  
Mengxiang Zhao ◽  
Liang Ding ◽  
Xihu Yang ◽  
...  
Keyword(s):  
Oxidative Phosphorylation ◽  
Mitochondrial Oxidative Phosphorylation ◽  
Metabolic Switch ◽  
Oxidative Phosphorylation System

Mitochondrial oxidative phosphorylation system is recruited to detergent-resistant lipid rafts during myogenesis

PROTEOMICS ◽  
2010 ◽  
Vol 10 (13) ◽  
pp. 2498-2515 ◽  
Author(s):  
Bong-Woo Kim ◽  
Joong-Won Lee ◽  
Hyo-Jung Choo ◽  
Chang Seok Lee ◽  
Soon-Young Jung ◽  
...  
Keyword(s):  
Oxidative Phosphorylation ◽  
Lipid Rafts ◽  
Mitochondrial Oxidative Phosphorylation ◽  
Oxidative Phosphorylation System
Sign in / Sign up

Export Citation Format

Share Document