EP10.14: Fetal cleft lip and palate: improved diagnostic accuracy by combined sonography (US) and magnetic resonance imaging (MRI)

Objective: To investigate cortical representation of articulation of the bilabial plosive in patients with cleft lip and palate. Design: We examined cortical representation for /pa/-articulation in cleft lip and palate patients using blood oxygenation level–dependent functional magnetic resonance imaging. Subjects: Data from four postsurgical adult cleft lip and palate patients were compared with those from six healthy volunteers. Results: Activation foci were found in the bilateral primary sensorimotor cortex in all cleft lip and palate patients, as in the controls. The sensorimotor cortex ipsilateral to the side of cleft lip and palate showed greater activation in unilateral cleft lip and palate patients, whereas the sensorimotor cortex contralateral to the side on which cheiloplasty had been performed earlier showed greater activation in a bilateral cleft lip and palate patient. Conclusions: The results suggest that there may be an ipsilateral dominance in cortical representation during bilabial articulation to the side of the cleft in the upper lip.

Download Full-text

PFM.39 Diagnostic accuracy of antenatal magnetic resonance imaging (MRI) to predict birth weight >90th centile or < 10th centile in the third trimester

Archives of Disease in Childhood - Fetal and Neonatal Edition ◽

10.1136/archdischild-2014-306576.269 ◽

2014 ◽

Vol 99 (Suppl 1) ◽

pp. A94.2-A95 ◽

Cited By ~ 2

Author(s):

G Malin ◽

D Anblagan ◽

G Bugg ◽

P Gowland ◽

NW Jones ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Birth Weight ◽

Magnetic Resonance ◽

Diagnostic Accuracy ◽

Resonance Imaging ◽

Third Trimester ◽

The Third ◽

Magnetic Resonance Imaging Mri

Download Full-text

Dynamic Analysis of Articulatory Movement Using Magnetic Resonance Imaging Movies: Methods and Implications in Cleft Lip and Palate

The Cleft Palate-Craniofacial Journal ◽

10.1597/03-007.1 ◽

2005 ◽

Vol 42 (3) ◽

pp. 225-230 ◽

Cited By ~ 29

Author(s):

Hideo Shinagawa ◽

Takashi Ono ◽

Ei-Ichi Honda ◽

Shinobu Masaki ◽

Yasuhiro Shimada ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Cleft Lip ◽

Cleft Lip And Palate ◽

Posterior Pharyngeal Wall ◽

Normal Volunteer ◽

Resonance Imaging ◽

Pharyngeal Wall ◽

Articulatory Movement ◽

The Subject

Objectives To visualize articulatory movement using a magnetic resonance imaging (MRI) movie of a subject with cleft lip and palate (CLP) and to demonstrate the usefulness of this method for studying oropharyngeal function. Material and Methods Dynamic changes in oropharyngeal structures were assessed with an MRI movie of a man with cleft lip and palate and in a normal adult male volunteer during the articulation of /pa/, /ta/, and /ka/. Results and Conclusions Different movement patterns were observed during articulation in the subject with CLP compared with the normal volunteer. Posterosuperior movement of the tongue and the anterior movement of the posterior pharyngeal wall were clearly visualized in the subject with CLP. Thus, MRI movies appear to be a promising tool for evaluating speech function in patients with CLP because of their noninvasive and nonradiation nature.

Download Full-text

Diagnostic accuracy of B-scan in predicting retinoblastoma in children, taking Magnetic Resonance Imaging of orbits as gold standard

Journal of the Pakistan Medical Association ◽

10.47391/jpma.1305 ◽

2020 ◽

pp. 1-7

Author(s):

Saba Murad ◽

Ishtiaq Ahmed ◽

Hania Ali ◽

Maria Ghani ◽

Sana Murad

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Diagnostic Accuracy ◽

Gold Standard ◽

Radiology Department ◽

Inclusion Criteria ◽

Resonance Imaging ◽

Cross Sectional ◽

Magnetic Resonance Imaging Mri ◽

Sensitivity Specificity

Abstract The objective of this study was to determine the diagnostic accuracy of B-scan in predicting retinoblastoma (Rb) taking Magnetic Resonance Imaging (MRI) as a gold standard. A cross-sectional validation study was conducted in the Radiology Department of Fauji Foundation Hospital from May 20 to Nov 20, 2017. Children fulfilling the inclusion criteria were selected after informed consent and detailed history was taken for investigation of Rb. B-scan of both eyes was done using 7.5-10 MHz probe, followed by MRI of both eyes in the same patients using 1.5 Tesla MRI machine with the help of qualified MRI technicians. Data analysis was done by SPSS version 16.0. The diagnostic accuracy, sensitivity, specificity, PPV and NPV of B-scan in prediction of Rb as compared to MRI was 90.45%, 82.28%, 90.54% and 90.28% respectively. The study concluded that diagnostic accuracy of B-scan as compared to MRI is substantial in Retinoblastoma. Continuous...

Download Full-text

Diagnostic accuracy of a five-point Likert scoring system for magnetic resonance imaging (MRI) evaluated according to results of MRI/ultrasonography image-fusion targeted biopsy of the prostate

BJU International ◽

10.1111/bju.13972 ◽

2017 ◽

Vol 121 (1) ◽

pp. 77-83 ◽

Cited By ~ 5

Author(s):

Toshitaka Shin ◽

Thomas B. Smyth ◽

Osamu Ukimura ◽

Nariman Ahmadi ◽

Andre Luis de Castro Abreu ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Diagnostic Accuracy ◽

Image Fusion ◽

Scoring System ◽

Targeted Biopsy ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Mri

Download Full-text

Combined Fmri and MRI Movie in the Evaluation of Articulation in Subjects with and without Cleft Lip and Palate

The Cleft Palate-Craniofacial Journal ◽

10.1597/07-070 ◽

2008 ◽

Vol 45 (3) ◽

pp. 309-314 ◽

Cited By ~ 6

Author(s):

Michiru Sato-Wakabayashi ◽

Maristela Sayuri Inoue-Arai ◽

Takashi Ono ◽

Ei-ichi Honda ◽

Tohru Kurabayashi ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Cleft Lip ◽

Cleft Lip And Palate ◽

Evaluation Methodology ◽

Precentral Gyrus ◽

Functional Magnetic Resonance ◽

Resonance Imaging ◽

Dynamic Movement ◽

Bilateral Cleft Lip

Objective: This study was undertaken to explore the application of functional magnetic resonance imaging (fMRI) and MRI movies in the evaluation of articulatory function in subjects with and without cleft lip and palate (CLP). Design: The authors examined brain activation and the dynamic movement of articulators during bilabial and velar plosives using fMRI and MRI movies. Subjects: Two subjects, one with unilateral cleft lip and palate (UCLP) and one with bilateral cleft lip and palate (BCLP), and 12 non-CLP volunteers. Results: Activation foci were found in the precentral gyrus, thalamus, and cerebellum in non-CLP volunteers. In comparison, similar regions were activated in the UCLP subject during both plosives, whereas the regions activated in the BCLP subject were different, particularly during the velar plosive. The dynamic movement of articulators in the UCLP subject was comparable to that in a non-CLP volunteer but different from that in the BCLP subject. Conclusions: The results suggest that these two MRI modalities may be a promising evaluation methodology for articulatory function in CLP from central and peripheral perspectives.

Download Full-text

Accuracy of endorectal Magnetic Resonance Imaging (MRI) and Dynamic Contrast Enhanced-MRI (DCE-MRI) in the preoperative local staging of prostate cancer

Urologia Journal ◽

10.5301/ru.2012.9207 ◽

2012 ◽

Vol 79 (2) ◽

pp. 116-122 ◽

Cited By ~ 7

Author(s):

Alessandro Baccos ◽

Riccardo Schiavina ◽

Ziv Zukerman ◽

Fiorenza Busato ◽

Caterina Gaudianol ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Prostate Cancer ◽

Magnetic Resonance ◽

Radical Prostatectomy ◽

Diagnostic Accuracy ◽

Resonance Imaging ◽

Mr Images ◽

Dce Mri ◽

Local Staging ◽

Magnetic Resonance Imaging Mri

Background The proper management of newly diagnosed prostate cancer (PCa) requires the choice of the appropriate treatment plan. A crucial factor is the accurate evaluation of the tumor local extension. The Magnetic Resonance Imaging (MRI) plays an important role in the local staging of prostate cancer, although its use in clinical practice is widely debated. Therefore, the purpose of our study was to evaluate the diagnostic accuracy of T2-weighted MR imaging in association with DCE-MRI, performed using an endorectal coil, in preoperative local staging of patients with prostate cancer, by using the histopathologic findings as the reference standard. Materials and Methods From April 2010 to May 2011, 65 patients (mean age, 65 years; range, 51–77 years) with clinical localized PCa, underwent radical prostatectomy at our institution, performed by 2 experienced surgeons. All patients were prospectively evaluated with eMRI in association with DCE-MRI prior to radical prostatectomy. In all patients MRI was performed at least 6 weeks after biopsy and within 2 weeks before Radical Prostatectomy (RP). Histologic analysis was our diagnostic “gold standard”. To ensure that the histopathological findings matched with MR images, the assessment of radiological images and the RP specimens were performed dividing the prostate in 14 regions. Results First, we performed a “per-patient” analysis, considering the entire prostate as a single region. Then, we performed a “per-emigland” analysis, finally a “per-region” analysis. The sensitivity, specificity, PPV, NPV and AUC in predicting ECE in the analysis “per-emigland” were respectively 66.7, 95.7, 66.7, 95.7, 0.824. The evaluation of SVI reported similar results: 62.5, 97.5, 62.5, 97.5, 0.797. DCE-MRI did not improve the diagnostic accuracy of T1-T2-weighted MR images in the evaluation of ECE or SVI. Conclusions T1-, T2-weighted MRI adds important information regarding the preoperative local staging of PCa. DCE-MRI does not improve the diagnostic accuracy of MRI in the local staging of PCa.

Download Full-text