P10.05: Quantitative 3D power Doppler ultrasound in the assessment of normal fetal brain blood flow: a reproducibility study of this method

ABSTRACT Advanced ultrasound technology has been a valuable tool in the assessment of placental anatomy and physiology. Conventional two-dimensional (2D) sonography reveals placental morphological characteristics, 2D color Doppler can assess blood flow in the placenta, 2D power Doppler can evaluate placental vascular trees, and three-dimensional (3D) ultrasound gives more detailed information on the surface anatomy. Recent advances, such as 3D power Doppler with virtual organ computer aided-analysis (VOCAL) and histogram analysis can measure the placental volume, and assess uteroplacental and fetoplacental perfusions. In particular, ‘placental vascular sonobiopsy’ can specifically evaluate the second- and thirdtrimester placental blood flow and vascularity by obtaining several spherical samples from the placenta that will represent the entire placenta. This article presents normal placental development and pathological findings of the placenta using 3D power Doppler ultrasound, and discusses 3D power Doppler assessments of placental perfusion in high-risk pregnancies, such as fetal growth restriction, pregnancy-induced hypertension and preeclampsia, and, from this basis, re-establishes the importance of 3D power Doppler ultrasound as a screening, diagnostic, and surveillance tool in normal and abnormal pregnancies. How to cite this article Tanaka H, Cajusay-Velasco S, Noguchi J, Hata T. Three-dimensional Power Doppler Ultrasound Study of the Placenta. Donald School J Ultrasound Obstet Gynecol 2014;8(4):400-409.

Download Full-text

An image processing technique for the visualization and quantification of blood flow entering the placenta using 3D power Doppler Ultrasound (PD-US)

Placenta ◽

10.1016/j.placenta.2016.06.086 ◽

2016 ◽

Vol 45 ◽

pp. 85 ◽

Cited By ~ 1

Author(s):

Gordon Stevenson ◽

Alec Welsh ◽

Lawrence Impey ◽

J. Alison Noble ◽

Sally Collins

Keyword(s):

Image Processing ◽

Blood Flow ◽

Doppler Ultrasound ◽

Power Doppler ◽

Processing Technique ◽

Image Processing Technique ◽

Power Doppler Ultrasound ◽

3D Power Doppler

Download Full-text

Chorionic Volume and Intervillous Blood Flow in Normal First Trimester Pregnancies Assessed by 3D Power Doppler Ultrasound

Donald School Textbook of Transvaginal Sonography ◽

10.5005/jp/books/10230_32 ◽

2005 ◽

pp. 384-384

Author(s):

Luis Merce ◽

Maria Barco ◽

Jose Arenas ◽

Rosa Sabatel

Keyword(s):

Blood Flow ◽

Doppler Ultrasound ◽

Power Doppler ◽

First Trimester ◽

Power Doppler Ultrasound ◽

3D Power Doppler

Download Full-text

The Influence of Hyperoxygenation on Fetal Brain Vascularity Measured Using 3D Power Doppler Ultrasound and the Index “Fractional Moving Blood Volume”

Fetal Diagnosis and Therapy ◽

10.1159/000517727 ◽

2021 ◽

pp. 1-9

Author(s):

Evitta Issa ◽

Gordon Niall Stevenson ◽

Ana Elizabeth Gomes De Melo Tavares Ferreira ◽

Melissa Han Yiin Chang ◽

Jennifer Alphonse ◽

...

Keyword(s):

Blood Volume ◽

Doppler Ultrasound ◽

Power Doppler ◽

Fetal Brain ◽

Threshold Effect ◽

Power Doppler Ultrasound ◽

Third Trimester ◽

3D Power Doppler ◽

Significant Difference ◽

Before And After

Introduction: Maternal hyperoxygenation effects on fetal cerebral hemodynamics are largely unknown. This study aimed to determine efficacy and reliability of a validated power Doppler ultrasound (US) index, fractional moving blood volume (FMBV), at measuring fetal cerebral vasculature changes during maternal hyperoxia. Methods: The fetal cerebral effects of 10 min of hyperoxygenation at 2 flow rates (52%/60% FiO2) were evaluated in women in their third trimester of pregnancy. 2D-US and 3D-US in a transverse plane were performed before, during, and following maternal hyperoxygenation with FMBV estimation performed offline. Results: Forty-five cases provided data for analysis. Mean intraobserver ICCs were 0.89 (3D-FMBV) and 0.84 (2D-FMBV). A significant difference in vascularity before and during and before and after 60% hyperoxia was observed (p < 0.05), whereas no significant differences were found at 52% hyperoxia (p > 0.05). Significant differences in vascularity were found between 2D-FMBV and 3D-FMBV (p < 0.01). Conclusion: Measurement of fetal cerebral vascularity by 3D-FMBV and 2D-FMBV was highly reproducible. The differing cerebral vascular changes seen with 60% but not 52% FiO2 suggest a possible “threshold effect” that may have influenced prior studies. Further studies are needed to assess cerebral effects of maternal hyperoxygenation on compromised fetuses.

Download Full-text