Multifocal cryptococcosis diagnosis by peripheral lymph node aspirates in a cat

2022 ◽  
Author(s):  
Sarah Butterfield ◽  
Charles R. J. Matthias ◽  
Joseph Fenn ◽  
Balazs Szladovits ◽  
Abbe H. Crawford
Keyword(s):  
Lymph Node ◽  
Peripheral Lymph Node ◽  
Peripheral Lymph

scholarly journals Characterization of a human homologue of the murine peripheral lymph node homing receptor.

1989 ◽  
Vol 109 (1) ◽  
pp. 421-427 ◽  
Author(s):  
B R Bowen ◽  
T Nguyen ◽  
L A Lasky
Keyword(s):  
Cell Adhesion ◽  
Lymph Node ◽  
Adhesion Molecule ◽  
Carbohydrate Binding ◽  
Human Homologue ◽  
Peripheral Lymph Node ◽  
Homing Receptor ◽  
Lymph Node Homing ◽  
Peripheral Lymph ◽  
Human Receptor

Lymphocyte trafficking is a fundamental aspect of the immune system that allows B and T lymphocytes with diverse antigen recognition specificities to be exposed to various antigenic stimuli in spatially distinct regions of an organism. A lymphocyte adhesion molecule that is involved with this trafficking phenomenon has been termed the homing receptor. Previous work (Lasky, L., T. Yednock, M. Singer, D. Dowbenko, C. Fennie, H. Rodriguez, T. Nguyen, S. Stachel, and S. Rosen. 1989. Cell. 56:1045-1055) has characterized a cDNA clone encoding a murine homing receptor that is involved in trafficking of lymphocytes to peripheral lymph nodes. This molecule was found to contain a number of protein motifs, the most intriguing of which was a carbohydrate binding domain, or lectin, that is apparently involved in the adhesive interaction between murine lymphocytes and peripheral lymph node endothelium. In this study, we have used the murine cDNA clone to isolate a human homologue of this peripheral lymph node-specific adhesion molecule. The human receptor was found to be highly homologous to the murine receptor in overall sequence, but showed no sequence similarity to another surface protein that may be involved with human lymphocyte homing, the Hermes glycoprotein. The extracellular region of the human receptor contained an NH2 terminally located carbohydrate binding domain followed by an EGF-like domain and a domain containing two repeats of a complement binding motif. Transient cell transfection assays using the human receptor cDNA showed that it encoded a surface glycoprotein that cross reacted with a polyclonal antibody directed against the murine peripheral lymph node homing receptor. Interestingly, the human receptor showed a high degree of sequence homology to another human cell adhesion glycoprotein, the endothelial cell adhesion molecule ELAM.

scholarly journals Epidemiology of Peripheral Lymph Node Tuberculosis and Genotyping of M. tuberculosis Strains: A Case-Control Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0132400 ◽  
Author(s):  
Chinmay Khandkar ◽  
Zinta Harrington ◽  
Peter J. Jelfs ◽  
Vitali Sintchenko ◽  
Claudia C. Dobler
Keyword(s):  
Lymph Node ◽  
Case Control Study ◽  
Case Control ◽  
Peripheral Lymph Node ◽  
Peripheral Lymph ◽  
Lymph Node Tuberculosis ◽  
Control Study

scholarly journals Demonstration that a lectin-like receptor (gp90MEL) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes.

1989 ◽  
Vol 109 (5) ◽  
pp. 2463-2469 ◽  
Author(s):  
J S Geoffroy ◽  
S D Rosen
Keyword(s):  
Lymph Node ◽  
Lymphoid Organ ◽  
Lymphoid Organs ◽  
Surface Glycoprotein ◽  
Lymphocyte Migration ◽  
Peripheral Lymph Node ◽  
Adhesive Interaction ◽  
High Endothelial Venules ◽  
Cell Surface Glycoprotein ◽  
Peripheral Lymph

Lymphocyte migration from the blood into most secondary lymphoid organs is initiated by a highly selective adhesive interaction with the endothelium of specialized blood vessels known as high endothelial venules (HEV). The propensity of lymphocytes to migrate to particular lymphoid organs is known as lymphocyte homing, and the receptors on lymphocytes that dictate interactions with HEV at particular anatomical sites are designated "homing receptors". Based upon antibody blockade experiments and cell-type distribution studies, a prominent candidate for the peripheral lymph node homing receptor in mouse is the approximately 90-kD cell surface glycoprotein (gp90MEL) recognized by the monoclonal antibody MEL-14. Previous work, including sequencing of a cDNA encoding for this molecule, supports the possibility that gp90MEL is a calcium-dependent lectin-like receptor. Here, we show that immunoaffinity-purified gp90MEL interacts in a sugar-inhibitable manner with sites on peripheral lymph node HEV and prevents attachment of lymphocytes. Lymphocyte attachment to HEV in Peyer's patches, a gut-associated lymphoid organ, is not affected by gp90MEL. The results demonstrate that gp90MEL, as a lectin-like receptor, directly bridges lymphocytes to the endothelium.

Peripheral Lymph Node Recurrence of Tuberculosis After Ustekinumab Treatment

2012 ◽  
Vol 148 (11) ◽  
pp. 1332 ◽  
Author(s):  
Ana I. Sánchez-Moya ◽  
Esteban Daudén
Keyword(s):  
Lymph Node ◽  
Peripheral Lymph Node ◽  
Lymph Node Recurrence ◽  
Peripheral Lymph

scholarly journals Recombinant anti-monkey CD3 immunotoxin depletes peripheral lymph node T lymphocytes more effectively than rabbit anti-thymocyte globulin in naïve baboons

2013 ◽  
Vol 29 (1-4) ◽  
pp. 60-63 ◽  
Author(s):  
Isaac Wamala ◽  
Abraham J. Matar ◽  
Evan Farkash ◽  
Zhirui Wang ◽  
Christene A. Huang ◽  
...  
Keyword(s):  
Lymph Node ◽  
T Lymphocytes ◽  
Peripheral Lymph Node ◽  
Peripheral Lymph

scholarly journals Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes specific functional barriers within the peripheral lymph node

2008 ◽  
Vol 38 (8) ◽  
pp. 2142-2155 ◽  
Author(s):  
Friederike Pfeiffer ◽  
Varsha Kumar ◽  
Stefan Butz ◽  
Dietmar Vestweber ◽  
Beat A. Imhof ◽  
...  
Keyword(s):  
Lymph Node ◽  
Endothelial Cell ◽  
Vascular Endothelial Cell ◽  
Molecular Composition ◽  
Cell Junctions ◽  
Vascular Endothelial ◽  
Peripheral Lymph Node ◽  
Peripheral Lymph

Effects of Heartworm and Intestinal Parasitic Infections on Hematology and Peripheral Lymph Node Cytology in Louisiana Dogs

1987 ◽  
Vol 16 (4) ◽  
pp. 97-101 ◽  
Author(s):  
K.A. Gossett ◽  
C.R. Root ◽  
B. Cleghorn ◽  
G.E. Church ◽  
J.R. Turk ◽  
...  
Keyword(s):  
Lymph Node ◽  
Parasitic Infections ◽  
Peripheral Lymph Node ◽  
Intestinal Parasitic Infections ◽  
Peripheral Lymph
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