scholarly journals High dose dual therapy and CYP2C19 polymorphism in Helicobacter pylori eradication

GastroHep ◽  
2021 ◽  
Author(s):  
Tin Ma Ma Win ◽  
Min Htun ◽  
Win Phyu Phyu Myint ◽  
Moe Myint Aung ◽  
Nwe Ni
Keyword(s):  
Helicobacter Pylori ◽  
Dual Therapy ◽  
High Dose ◽  
Helicobacter Pylori Eradication ◽  
Cyp2c19 Polymorphism

scholarly journals High dose dual therapy versus bismuth quadruple therapy for Helicobacter pylori eradication treatment

Medicine ◽  
2019 ◽  
Vol 98 (7) ◽  
pp. e14396 ◽  
Author(s):  
Xue Yang ◽  
Jin-Xia Wang ◽  
Sheng-Xi Han ◽  
Cai-Ping Gao
Keyword(s):  
Helicobacter Pylori ◽  
Dual Therapy ◽  
High Dose ◽  
Helicobacter Pylori Eradication ◽  
Quadruple Therapy

M1121 Comparative Study of Helicobacter pylori Eradication Rates of Three-Times-Daily High Dose Lansoprazole/Amoxicillin Dual Therapy Versus Standard Triple Therapy

2010 ◽  
Vol 138 (5) ◽  
pp. S-336-S-337
Author(s):  
Seung Young Kim ◽  
Sung Woo Jung ◽  
Jin Nam Kim ◽  
Jeong Han Kim ◽  
Hyung Joon Yim ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Comparative Study ◽  
Triple Therapy ◽  
Dual Therapy ◽  
High Dose ◽  
Helicobacter Pylori Eradication ◽  
Standard Triple Therapy

scholarly journals 564 Efficacy of Optimized High Dose Dual Therapy, Sequential Therapy and Triple Therapy in Helicobacter pylori Eradication—A Prospective, Comparative, Randomized Control Study

2014 ◽  
Vol 146 (5) ◽  
pp. S-103
Author(s):  
Jyh-Chin Yang ◽  
Chun-Jung Lin ◽  
Jin-De Chen ◽  
Hong-Long Wang ◽  
Chia-Tung Shun ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Sequential Therapy ◽  
Dual Therapy ◽  
High Dose ◽  
Helicobacter Pylori Eradication ◽  
Randomized Control Study ◽  
Randomized Control ◽  
Control Study

scholarly journals The Application of High-Dose Proton Pump Inhibitor Induction Treatment before Dual Therapy for Helicobacter pylori Eradication: An Open-Label Random Trial

2021 ◽  
Vol 10 (19) ◽  
pp. 4352
Author(s):  
Li-Wei Chen ◽  
Liang-Che Chang ◽  
Chung-Ching Hua ◽  
Ching-Jung Liu ◽  
Tien-Shin Chou ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Eradication Therapy ◽  
Dual Therapy ◽  
Induction Treatment ◽  
High Dose ◽  
Success Rates ◽  
Open Label ◽  
Helicobacter Pylori Eradication ◽  
H Pylori

This was a prospective, randomized, open-label trial. Patients without previous Helicobacter pylori eradication therapy were randomly assigned to either a high-dose dual therapy (HDDT) group or a traditional clarithromycin/amoxicillin triple therapy (CATT) group. In the HDDT group, patients took rabeprazole, 20 mg, four times per day for three days and then dual therapy with rabeprazole, 20 mg, and amoxicillin, 500 mg, four times per day during the patient’s breakfast, lunch, dinner, and bedtime for 14 days. In the CATT group, patients received conventional triple therapy for 14 days (rabeprazole 20 mg, amoxicillin 1 g, and clarithromycin 500 mg twice per day). In the HDDT group, the success rates of H. pylori eradication were 91.7% (95% confidence interval (CI): 0.78–0.97) by intention-to-treat (ITT) and 94.3% (95% CI: 0.79–0.99) by per-protocol (PP) analysis. In the CATT group, the eradication rates were 77.1% (95% CI: 0.61–0.87) by ITT and 84.3% (95% CI: 0.66–0.94) by PP analysis. The study completion rates were 97.2% (35/36) in the HDDT group. Three-day high-dose rabeprazole induction treatment before dual therapy and a schedule of taking the drug at meal and bed times could achieve an acceptable H. pylori eradication rate (>90%) and good drug compliance.

scholarly journals High-dose amoxicillin/esomeprazole dual therapy as a first-line therapy for Helicobacter pylori eradication

2018 ◽  
Vol 26 (6) ◽  
pp. 353 ◽  
Author(s):  
Cai-Ping Gao ◽  
Xun Xiao ◽  
Pei-Xi Liu ◽  
Zhou Zhou ◽  
Liang-Ping Li ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Dual Therapy ◽  
High Dose ◽  
First Line ◽  
Helicobacter Pylori Eradication ◽  
First Line Therapy ◽  
Line Therapy

10‐Day and 14‐day high‐dose dual therapy for the treatment of Helicobacter pylori : A propensity score matching analysis

Helicobacter ◽  
2021 ◽  
Author(s):  
Pei‐Ying Zou ◽  
Jie Hu ◽  
Jing‐Tao Zhao ◽  
Zhe Zhao ◽  
Hao Mei ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Dual Therapy ◽  
High Dose ◽  
Propensity Score Matching Analysis
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