α-Galactosidase Stimulates Acetylcholine Receptor Aggregation in Skeletal Muscle Cells via PNA-Binding Carbohydrates

2000 ◽  
Vol 270 (3) ◽  
pp. 899-902 ◽  
Author(s):  
Natasha Parkhomovskiy ◽  
Paul T Martin
Keyword(s):  
Skeletal Muscle ◽  
Acetylcholine Receptor ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Receptor Aggregation

scholarly journals Acetylcholine receptor clustering and nuclear movement in muscle fibers in culture.

1987 ◽  
Vol 104 (1) ◽  
pp. 87-95 ◽  
Author(s):  
L L Englander ◽  
L L Rubin
Keyword(s):  
Skeletal Muscle ◽  
Cell Culture ◽  
Extracellular Matrix ◽  
Acetylcholine Receptor ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Nuclear Movement ◽  
Stable Source ◽  
Achr Clustering ◽  
Cluster Nucleus

We have studied the formation of acetylcholine receptor (AChR) clusters and the behavior of myonuclei in rat and chick skeletal muscle cells grown in cell culture. These cells were treated with a factor derived from Torpedo electric extracellular matrix, which causes a large increase in their number of AChR clusters. We found that these clusters were located preferentially in membrane regions above myonuclei. This cluster-nucleus colocalization is explained by our finding that most of the nuclei near clusters remain relatively stationary, while most of those away from clusters are able to translocate throughout the myotube. In some cases, clusters clearly formed first, then nuclei migrated underneath and became immobilized. If clustered AChRs later dispersed, their associated nuclei resumed moving. These results suggest that AChR clustering initiates an extensive cytoskeletal rearrangement that causes the subcluster localization of organelles, potentially providing a stable source of newly synthesized AChRs for insertion into the cluster.

scholarly journals Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells

2014 ◽  
Vol 8 ◽  
Author(s):  
Evelyn C. Avilés ◽  
Cristina Pinto ◽  
Patricia Hanna ◽  
Jorge Ojeda ◽  
Viviana Pérez ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Acetylcholine Receptor ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Receptor Clustering

Extracts of Hymenocardia acida ameliorate insulin resistance in skeletal muscle cells

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
II Ezeigbo ◽  
C Wheeler-Jones ◽  
S Gibbons ◽  
ME Cleasby
Keyword(s):  
Insulin Resistance ◽  
Skeletal Muscle ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Ameliorate Insulin Resistance

TGFß regulates metabolism of human skeletal muscle cells by miRNAs

2018 ◽  
Author(s):  
S Höckele ◽  
P Huypens ◽  
C Hoffmann ◽  
T Jeske ◽  
M Hastreiter ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Human Skeletal Muscle ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Human Skeletal Muscle Cells
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