Prolactin, Growth Hormone, and Luteinizing Hormone-β Subunit Gene Expression in the Cephalic and Caudal Lobes of the Anterior Pituitary Gland during Embryogenesis and Different Reproductive Stages in the Chicken

1994 ◽  
Vol 96 (2) ◽  
pp. 197-205 ◽  
Author(s):  
Norio Kansaku ◽  
Kiyoshi Shimada ◽  
Osamu Terada ◽  
Noboru Saito





1992 ◽  
Vol 12 (6) ◽  
pp. 2624-2632
Author(s):  
D Murphy ◽  
K Pardy ◽  
V Seah ◽  
D Carter

In thyroid hormone-depleted rats, the rate of transcription of the growth hormone (GH) gene in the anterior pituitary gland is lower than the rate in euthyroid controls, and there is a corresponding reduction in the abundance of the GH mRNA. Concomitantly, the poly(A) tail of the GH mRNA increases in length. Examination of nuclear RNA from anterior pituitary glands of control and thyroid hormone-depleted rats revealed no difference in the length of pre-mRNAs containing the first and last introns of the GH gene. However, mature nuclear GH RNA is differentially polyadenylated in euthyroid and hypothyroid animals. We suggest that the extent of polyadenylation of the GH transcript is regulated in the cell nucleus concomitant with or subsequent to the splicing of the pre-mRNA. Experiments with anterior pituitary gland explant cultures demonstrated that the GH mRNA from thyroid hormone-depleted rats is more stable than its euthyroid counterpart and that the poly(A) tail may contribute to the differential stability of free GH ribonucleoproteins.





2004 ◽  
Vol 287 (5) ◽  
pp. E818-E819 ◽  
Author(s):  
H. Maurice Goodman

This essay looks at the historical significance of an APS classic paper that is freely available online: Fevold HL, Hisaw FL, Leonard SL. The gonad stimulating and the luteinizing hormones of the anterior lobe of the hypophesis. Am J Physiol 97: 291—301, 1931 ( http://ajplegacy.physiology.org/cgi/reprint/97/2/291 ).



1974 ◽  
Vol 56 (4) ◽  
pp. 1052-1059 ◽  
Author(s):  
Pierre Borgeat ◽  
Fernand Labrie ◽  
Jacques Drouin ◽  
Alain Bélanger ◽  
Hans Immer ◽  
...  


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