scholarly journals Herpes Simplex Virus Type 1 VP26 Is Not Essential for Replication in Cell Culture but Influences Production of Infectious Virus in the Nervous System of Infected Mice

Virology ◽  
1998 ◽  
Vol 247 (1) ◽  
pp. 115-124 ◽  
Author(s):  
Prashant Desai ◽  
Neal A. DeLuca ◽  
Stanley Person
Keyword(s):  
Cell Culture ◽  
Nervous System ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Infectious Virus ◽  
Simplex Virus

Herpes Simplex Virus Type 1 Infection of the Rat Enteric Nervous System Evokes Small-Bowel Neuromuscular Abnormalities

2010 ◽  
Vol 138 (5) ◽  
pp. 1790-1801 ◽  
Author(s):  
Paola Brun ◽  
Maria Cecilia Giron ◽  
Chiara Zoppellaro ◽  
Anna Bin ◽  
Andrea Porzionato ◽  
...  
Keyword(s):  
Nervous System ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Small Bowel ◽  
Enteric Nervous System ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuromuscular Abnormalities ◽  
Simplex Virus

Survival of Herpes Simplex Virus Type 1 on Some Common Foods Routinely Touched before Consumption

1997 ◽  
Vol 60 (10) ◽  
pp. 1259-1261 ◽  
Author(s):  
D. BARDELL
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Infectious Virus ◽  
Virus Infectivity ◽  
Refrigerator Temperature ◽  
Simplex Virus ◽  
Infectivity Titer

Droplets of saliva containing herpes simplex virus type 1 were placed on the skin of tomatoes and the upper surface of lettuce leaves. There was no loss of virus infectivity titer at refrigerator temperature (2°C) at any time examined up to 1 h, the longest period tested. At room temperature (22 to 24°C) there was a 2-log drop in titer between 30 and 60 min, but some infectious virus was still present at 1 h. The virus-containing saliva remained in a liquid state at 2°C. At 22 to 24°C the droplets became dry at approximately 50 min. Implications of the findings are discussed.

scholarly journals Herpes Simplex Virus Type 1 Cytoplasmic Envelopment Requires Functional Vps4

2007 ◽  
Vol 81 (14) ◽  
pp. 7380-7387 ◽  
Author(s):  
Colin M. Crump ◽  
Catherine Yates ◽  
Tony Minson
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Infectious Virus ◽  
Virus Production ◽  
Dominant Negative ◽  
Simplex Virus ◽  
Multivesicular Endosomes

ABSTRACT The assembly and egress of herpesviruses are complex processes that require the budding of viral nucleocapsids into the lumen of cytoplasmic compartments to form mature infectious virus. This envelopment stage shares many characteristics with the formation of luminal vesicles in multivesicular endosomes. Through expression of dominant-negative Vps4, an enzyme that is essential for the formation of luminal vesicles in multivesicular endosomes, we now show that Vps4 function is required for the cytoplasmic envelopment of herpes simplex virus type 1. This is the first example of a large enveloped DNA virus engaging the multivesicular endosome sorting machinery to enable infectious virus production.

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