Multivalent synthetic peptide vaccine against schistosomiasis: Preparation of multiple antigenic peptide

Author(s):  
Jia-Xi Xu
1987 ◽  
Vol 166 (5) ◽  
pp. 1591-1596 ◽  
Author(s):  
F Zavala ◽  
J P Tam ◽  
P J Barr ◽  
P J Romero ◽  
V Ley ◽  
...  

A synthetic peptide, (DPPPPNPN)2D, representing a subunit of the repeat domain of the Plasmodium berghei circumsporozoite protein, was conjugated to tetanus toxoid using bisdiazobenzidine. Immunization of mice and rats with the conjugate induced high serum titers of antibodies to the parasite, and most of the animals were completely protected from malaria infection when challenged with sporozoites.


2016 ◽  
Vol 196 (8) ◽  
pp. 3364-3374 ◽  
Author(s):  
Manisha Pandey ◽  
Rasmus Mortensen ◽  
Ainslie Calcutt ◽  
Jessica Powell ◽  
Michael R. Batzloff ◽  
...  

1991 ◽  
Vol 72 (3) ◽  
pp. 557-565 ◽  
Author(s):  
A. Snijders ◽  
B. J. Benaissa-Trouw ◽  
T. A. M. Oosterlaken ◽  
W. C. Puijk ◽  
W. P. A. Posthumus ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document