A Prospective, Randomized, Controlled Trial Comparing the Results of Microdiscectomy Under Regional and General Anesthesia

2006 ◽  
pp. 1-5
Author(s):  
Thanet Wattanawong ◽  
Petchara Chamnankitkosol ◽  
Patarawan Woratanarat
Keyword(s):  
Randomized Controlled Trial ◽  
General Anesthesia ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial

Acupuncture accelerates recovery after general anesthesia: a prospective randomized controlled trial

2015 ◽  
Vol 13 (2) ◽  
pp. 99-104 ◽  
Author(s):  
Marco Gemma ◽  
Elisa Nicelli ◽  
Luigi Gioia ◽  
Elena Moizo ◽  
Luigi Beretta ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
General Anesthesia ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial

scholarly journals Clinical performance of Ambu AuraGainTM versus i-gelTM in anesthetized children: a prospective, randomized controlled trial

2020 ◽  
Vol 15 (2) ◽  
pp. 173-180
Author(s):  
Ji-Hyun Lee ◽  
Seungpyo Nam ◽  
Young-Eun Jang ◽  
Eun-Hee Kim ◽  
Hee-Soo Kim ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
General Anesthesia ◽  
Clinical Performance ◽  
Controlled Trial ◽  
Catheter Placement ◽  
Suction Catheter ◽  
Success Rates ◽  
Emergence Period ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial

Background: Ambu AuraGain and i-gel have different characteristics in design each other. However, few reports evaluate which device has more benefits for ventilation in children undergoing paralyzed general anesthesia. This prospective, randomized controlled trial compared the clinical performance AuraGain and i-gel in anesthetized children.Methods: Children aged between 1 month and 7 years undergoing elective surgery were randomly assigned to the AuraGain and i-gel groups. The primary outcome was initial oropharyngeal leak pressure (OLP). Secondary outcomes were OLP at 10 min post-insertion, first-attempt and total insertion success rates, number of attempts and ease of gastric suction catheter placement, peak inspiratory pressure, fiberoptic bronchoscopic view score, ventilation quality, requirement of additional manipulation post-insertion, and complications.Results: Data of 93 patients were analyzed. The initial OLPs of the AuraGain and i-gel were 27.5 ± 7.7 and 25.0 ± 8.0 cmH2O, respectively (P = 0.13). The OLP was significantly increased 10 min post-insertion in both groups. The initial success rates of the AuraGain and i-gel insertion were comparable. Suction catheter placement via the gastric port was easier (P = 0.02) and fiberoptic bronchoscopic view was better with the AuraGain (P < 0.001). The i-gel required additional manipulations post-insertion (P = 0.04). The incidence of complications during the emergence period was 2.2% for the i-gel and 10.8% for the AuraGain (P = 0.1)Conclusions: OLP is comparable between AuraGain and i-gel. The AuraGain would be more favorable than the i-gel for use in pediatric patients under general anesthesia considering other outcomes.

scholarly journals Comparison of a small dose of oxycodone and sufentanil for the prevention of sufentanil-induced cough during general anesthesia induction: a prospective randomized controlled trial

2021 ◽  
Author(s):  
Lingli Shi ◽  
Yong He ◽  
Huanhuan Ni
Keyword(s):  
Randomized Controlled Trial ◽  
General Anesthesia ◽  
Small Dose ◽  
Elective Surgery ◽  
Controlled Trial ◽  
Anesthesia Induction ◽  
Clinical Trial Registry ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Hemodynamic State

Abstract Background: Sufentanil is widely used during anesthesia induction. However, sufentanil injections can cause cough through different mechanisms. This study aimed to evaluate the effectiveness of a small dose of oxycodone and sufentanil in suppressing sufentanil-induced cough (SIC) during general anesthesia induction.Methods: This prospective, randomized, controlled trial was conducted form February 12, 2019 to December 30, 2019. A total of 174 patients were scheduled for elective surgery, and 144 screened patients were randomly divided into 3 groups (n=48). Five minutes before sufentanil bolus (0.4 μg/kg), patients in group O received 0.02 mg/kg oxycodone intravenously within 5 s, those in group S received 0.02 μg/kg sufentanil within 5 s and those in group N received an equal volume of 0.9% normal saline within 5 s. Sufentanil was diluted to 5 μg/ml and administered within 5 s after pretreatment. The incidence and severity of cough in the three groups were evaluated within 1 minute after sufentanil injection during anesthesia induction. Mean arterial pressure (MAP) and heart rate (HR) were recorded at T0 (after entering the operation), T1 (3 minutes after pretreatment), T2 (before intubation), and T3 (1 minute after intubation).Results: The incidences of cough in group N, group O, and group S were 20 (41.6%), 7 (14.5%), and 6 (12.5%), respectively. Compared with group N, group O and group S exhibited significantly reduced incidence and severity of cough, and the severity of cough in group O and group S was dramatically reduced compared with that in group N (P<0.05). No significant differences in the rangeability of MAP and HR were noted at the four time points in the three groups (P> 0.05).Conclusion: Intravenous oxycodone (0.02 mg/kg) and sufentanil (0.02 μg/kg) represent effective approaches to reducing SIC in anesthesia induction and ensuring a relatively stable hemodynamic state during general anesthesia induction.Trial registration: Chinese Clinical Trial Registry (ChiCTR1900021087, registered date: January 28, 2019), http://www.chictr.org.cn

scholarly journals Effectiveness of early postoperative oral hydration after colorectal surgery with general anesthesia: A prospective randomized controlled trial

2019 ◽  
Author(s):  
Xiaorong Yin ◽  
Lei Yang ◽  
Shunju Xiang ◽  
Yixuan Wu ◽  
Qian Li
Keyword(s):  
Randomized Controlled Trial ◽  
Colorectal Surgery ◽  
General Anesthesia ◽  
Controlled Trial ◽  
Nausea And Vomiting ◽  
Oral Hydration ◽  
Elective Colorectal Surgery ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Safety Outcomes

Abstract BACKGROUND: Over the last decades, studies have already demonstrated that early feeding in patients after elective colorectal surgery yielded a shorter length of hospital stay and did not cause additional risk for adverse events. However, the optimal timing for beginning oral hydration after colorectal surgery under general anesthesia remains controversial. Therefore, we conducted the study to evaluate the effects of early oral hydration (EOH) versus traditional oral hydration (TOH) on thirst and clinical safety outcomes after colorectal surgery under general anesthesia. METHODS: This prospective randomized controlled trial of 1,000 patients with American Society of Anesthesiologists I–III who underwent colorectal surgery under general anesthesia were randomly assigned to the EOH group (given 0.5 ml/kg water after recovery from general anesthesia) or TOH group (fasting and water deprivation until postoperative intestine function recovery). The primary outcome was thirst scale, and secondary outcomes were discomfort score, nausea and vomiting score, and safety outcomes. RESULTS: Of the 1,000 patients who underwent randomization at initial stage, 27 were excluded in EOH group because of refusal (n=22) or nausea and vomiting before hydration (n=5). Demographic and operative data were similar, but not statistically significant (P>0.05). Patients who received EOH were associated with lower thirst score than with TOH (EOH 45.70±24.51 vs. TOH 62.20±23.99; P<0.001) and oropharyngeal discomfort scale (EOH 3.71±8.49 vs. TOH 6.18±11.89, P<0.0001) 30 min after drinking. No significant differences were found for the time of intestinal movements (EOH 73.37±34.49 h, TOH 70.56±31.71, P=0.187) and for EOH and TOH for the risk of nausea and vomiting at the postoperative period (P>0.05) and other complications (P>0.05). CONCLUSIONS: The findings suggested the safety outcomes for mild EOH on patients after colorectal surgery under general anesthesia. Patients who received EOH could have significantly reduced degree of thirst scale and oropharyngeal discomfort scale 30 min after drinking. Trial registration: CHiCTR, CHiCTR-TRC-13003097. Registered 11 March2013, http://www.chictr.org.cn/showproj.aspx?proj=6462.

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