scholarly journals Surgical Treatment of Type 2 Diabetes Mellitus in Youth

Author(s):  
Anna Zenno ◽  
Evan P. Nadler
2019 ◽  
Vol 72 (5) ◽  
pp. 739-743
Author(s):  
Oleksandr Yu. Ioffe ◽  
Mykola S. Kryvopustov ◽  
Yuri A. Dibrova ◽  
Yuri P. Tsiura

Introduction: Morbid obesity (MO) has a significant impact on mortality, health and quality of life of patients. Type 2 diabetes mellitus (T2DM) is a common comorbidity in patients with MO. The aim is to study T2DM remission and to develop a prediction model for T2DM remission after two-stage surgical treatment of patients with MO. Materials and methods: The study included 97 patients with MO. The mean BMI was 68.08 (95% CI: 66.45 - 69.71) kg/m2. 70 (72,2%) patients with MO were diagnosed with T2DM. The first stage of treatment for the main group (n=60) included the IGB placement, for the control group (n=37) - conservative therapy. In the second stage of treatment the patients underwent bariatric surgery. The study addresses such indicators as BMI, percentage of weight loss, percentage of excess weight loss, ASA physical status class, fasting glucose level, HbA1c, C-peptide. Results: Two-stage treatment of morbidly obese patients with T2DM promotes complete T2DM remission in 68.1% of patients. The risk prediction model for failure to achieve complete T2DM remission 12 months after LRYGB based on a baseline C-peptide level has a high predictive value, AUC = 0.84 (95% CI: 0.69-0.93), OR = 0.23 ( 95% CI: 0.08-0.67). Conclusions: Two-stage treatment of patients with MO promotes improvement of carbohydrate metabolism indicators. With a C-peptide level > 3.7 ng/ml, prediction of complete T2DM remission 12 months after Laparoscopic Roux-en-Y Gastric Bypass is favorable.


The Lancet ◽  
2001 ◽  
Vol 358 (9282) ◽  
pp. 668-669 ◽  
Author(s):  
Francesco Rubino ◽  
Michel Gagner ◽  
Jacques Marescaux

2012 ◽  
Vol 23 (2) ◽  
pp. 234-240 ◽  
Author(s):  
Enrique Lanzarini ◽  
Attila Csendes ◽  
Luis Gutierrez ◽  
Pedro Cuevas ◽  
Hanns Lembach ◽  
...  

2010 ◽  
Vol 6 (3) ◽  
pp. S22-S23
Author(s):  
Marcos Berry ◽  
Patricio Lamoza ◽  
Marcelo Fajardo ◽  
Rodolfo Lahsen ◽  
Lionel Urrutia

Sign in / Sign up

Export Citation Format

Share Document