Protective Role of Heat Shock Proteins During Neurodegeneration in Parkinson’s Disease

2020 ◽  
Author(s):  
Amr Ghit
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Protective Role ◽  
Shock Proteins

Protective Role of Heat Shock Proteins in Parkinson’s Disease

2011 ◽  
Vol 8 (4) ◽  
pp. 155-168 ◽  
Author(s):  
Paolo Aridon ◽  
Fabiana Geraci ◽  
Giuseppina Turturici ◽  
Marco D’Amelio ◽  
Giovanni Savettieri ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Protective Role ◽  
Shock Proteins

scholarly journals Humoral Response against Small Heat Shock Proteins in Parkinson’s Disease

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0115480 ◽  
Author(s):  
Ewa Papuć ◽  
Ewa Kurys-Denis ◽  
Witold Krupski ◽  
Konrad Rejdak
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Humoral Response ◽  
Small Heat Shock Proteins ◽  
Shock Proteins

P3-167 Specific association of small heat shock proteins with the pathological features of Alzheimer's and Parkinson's disease brains

2004 ◽  
Vol 25 ◽  
pp. S403
Author(s):  
Micha M. Wilhelmus ◽  
Irene Otte-Höller ◽  
Rob A.I. de Vos ◽  
Ernst Jansen Steur ◽  
Pieter Wesseling ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Small Heat Shock Proteins ◽  
Pathological Features ◽  
Specific Association ◽  
Shock Proteins

Protective role of TAT-HSP70 after myocardial I/R injury

2017 ◽  
Vol 5 (3) ◽  
pp. 279-284
Author(s):  
Martin A. Meenakshi ◽  
Erik G. Seth
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Protective Role ◽  
Inflammatory Mechanism ◽  
Myocardial Ischemia Reperfusion Injury ◽  
Myocardial Ischemia Reperfusion ◽  
Shock Proteins

Myocardial ischemia reperfusion injury I/R adversely affects cardiac function. Heat shock proteins (HSPs) are a highly conserved family of proteins with diverse functions expressed by all cells exposed to environmental stress including myocardila injury. We investigated release of small constitutive heat shock proteins (HSPs) from mouse myocardium and the effects of TAT-HSP70 after myocardial I/R via occluding the left coronary artery (LAD). The results support the hypothesis that elevated HSPs in myocardium after ischemia and reperfusion and contributes to the inflammatory mechanism of myocardial functional injury. Further investigation of the significance of HSPs accumulation to the evolution of myocardial injury.

scholarly journals The role of heat shock proteins in kidney disease

2016 ◽  
Vol 4 (3) ◽  
pp. 114-117 ◽  
Author(s):  
Shobhana Nayak Rao
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Neurodegenerative Disorders ◽  
Kidney Diseases ◽  
Kidney Injury ◽  
Protective Role ◽  
The Family ◽  
Intracellular Proteins ◽  
Shock Proteins

AbstractHeat Shock Proteins (HSP) belong to the family of intracellular proteins that are constitutively expressed and are upregulated by various stressors including heat, oxidative and chemical stress. HSP helps in reparative processes, including the refolding of damaged proteins and the removal of irreparably damaged proteins that would initiate cellular death or apoptosis. A growing body of evidence has expanded the role of HSP and defined their role in diseases such as neurodegenerative disorders, cancer, ischemic heart disease and kidney diseases. The protective role of HSP in ischemic renal injury has been described and HSP impairment has been noted in other forms of kidney injuries including post-transplant situation. Further research into the role of HSP in prevention of kidney injury is crucial if translation from the laboratory to patient bedside has to occur. This article aims to be a review of heat shock protein, and its relevance to kidney diseases.

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