Reelin and Radial Glial Cells

2008 ◽  
pp. 159-169
Author(s):  
Eckart Förster ◽  
Shanting Zhao ◽  
Michael Frotscher
Keyword(s):  
Glial Cells ◽  
Radial Glial Cells ◽  
Radial Glial

scholarly journals Neuronal Regeneration from Ependymo-Radial Glial Cells: Cook, Little Pot, Cook!

2015 ◽  
Vol 32 (4) ◽  
pp. 516-527 ◽  
Author(s):  
Catherina G. Becker ◽  
Thomas Becker
Keyword(s):  
Glial Cells ◽  
Neuronal Regeneration ◽  
Radial Glial Cells ◽  
Radial Glial

scholarly journals Radial glial cells as neuronal precursors: The next generation?

2002 ◽  
Vol 69 (6) ◽  
pp. 708-713 ◽  
Author(s):  
Christopher T. Gregg ◽  
Andrew K. Chojnacki ◽  
Samuel Weiss
Keyword(s):  
Glial Cells ◽  
Next Generation ◽  
Radial Glial Cells ◽  
Neuronal Precursors ◽  
Radial Glial

scholarly journals Metabolic regulation and glucose sensitivity of cortical radial glial cells

2018 ◽  
Vol 115 (40) ◽  
pp. 10142-10147 ◽  
Author(s):  
Brian G. Rash ◽  
Nicola Micali ◽  
Anita J. Huttner ◽  
Yury M. Morozov ◽  
Tamas L. Horvath ◽  
...  
Keyword(s):  
Glial Cells ◽  
Metabolic Regulation ◽  
Physiological Mechanism ◽  
Metabolic Disturbances ◽  
Mitochondrial Transport ◽  
Radial Glial Cells ◽  
Intracellular Ca ◽  
Glucose Sensitivity ◽  
Radial Glial ◽  
Primary Stem

The primary stem cells of the cerebral cortex are the radial glial cells (RGCs), and disturbances in their operation lead to myriad brain disorders in all mammals from mice to humans. Here, we found in mice that maternal gestational obesity and hyperglycemia can impair the maturation of RGC fibers and delay cortical neurogenesis. To investigate potential mechanisms, we used optogenetic live-imaging approaches in embryonic cortical slices. We found that Ca2+signaling regulates mitochondrial transport and is crucial for metabolic support in RGC fibers. Cyclic intracellular Ca2+discharge from localized RGC fiber segments detains passing mitochondria and ensures their proper distribution and enrichment at specific sites such as endfeet. Impairment of mitochondrial function caused an acute loss of Ca2+signaling, while hyperglycemia decreased Ca2+activity and impaired mitochondrial transport, leading to degradation of the RGC scaffold. Our findings uncover a physiological mechanism indicating pathways by which gestational metabolic disturbances can interfere with brain development.

Radial Glial Cells

2013 ◽  
Author(s):  
Magdalena Götz
Keyword(s):  
Glial Cells ◽  
Topic Area ◽  
Radial Glial Cells ◽  
Radial Glial ◽  
Digitally Enhanced

This is a digitally enhanced text. Readers can also see the coverage of this topic area in the second edition of Neuroglia. The second edition of Neuroglia was first published digitally in Oxford Scholarship Online and the bibliographic details provided, if cited, will direct people to that version of the text. Readers can also see the coverage of this topic area in the ...

scholarly journals Genes and Mechanisms Involved in the Generation and Amplification of Basal Radial Glial Cells

2019 ◽  
Vol 13 ◽  
Author(s):  
Maxime Penisson ◽  
Julia Ladewig ◽  
Richard Belvindrah ◽  
Fiona Francis
Keyword(s):  
Glial Cells ◽  
Radial Glial Cells ◽  
Radial Glial

scholarly journals Radial glial cells derived from the neonatal rat spinal cord: morphological and immunocytochemical characterization

2005 ◽  
Vol 68 (5) ◽  
pp. 361-369 ◽  
Author(s):  
Marjan Moreels ◽  
Frank Vandenabeele ◽  
Leen Deryck ◽  
Ivo Lambrichts
Keyword(s):  
Spinal Cord ◽  
Glial Cells ◽  
Neonatal Rat ◽  
Rat Spinal Cord ◽  
Radial Glial Cells ◽  
Radial Glial

Developmentally regulated and spatially restricted antigens of radial glial cells

1993 ◽  
Vol 197 (4) ◽  
pp. 307-318 ◽  
Author(s):  
Jean-Paul Herman ◽  
John C. Victor ◽  
Joshua R. Sanes
Keyword(s):  
Glial Cells ◽  
Developmentally Regulated ◽  
Radial Glial Cells ◽  
Radial Glial
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