Using Bronchoalveolar Lavage to Evaluate Changes in Pulmonary Diseases

2020 ◽  
pp. 117-128
Author(s):  
Marissa E. Di ◽  
Dandan Yang ◽  
Y. Peter Di
Keyword(s):  
Bronchoalveolar Lavage ◽  
Pulmonary Diseases

Feasibility of microRNA Measurements in Routine Bronchoalveolar Lavage (BAL) and Bronchial Washings in Patients With Lung Cancer and Nonmalignant Pulmonary Diseases

CHEST Journal ◽  
2014 ◽  
Vol 145 (3) ◽  
pp. 342A ◽  
Author(s):  
Amanda Tufman ◽  
Fernando Gamarra ◽  
Rosi Kiefl ◽  
S. Kaduthanam ◽  
Ruprecht Kuner ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Bronchoalveolar Lavage ◽  
Pulmonary Diseases

scholarly journals Concordance of Bronchoalveolar Lavage Cytology with Transbronchial Lung Biopsies in Non-neoplastic Pulmonary Diseases

2021 ◽  
Author(s):  
Nischita Jayaraj ◽  
Kusuma Venkatesh
Keyword(s):  
Bronchoalveolar Lavage ◽  
Interstitial Pneumonia ◽  
Lung Diseases ◽  
Correct Diagnosis ◽  
Usual Interstitial Pneumonia ◽  
Granulomatous Inflammation ◽  
Pulmonary Diseases ◽  
Differential Count ◽  
Flexible Bronchoscope ◽  
Cell Counts

Introduction: In many pulmonary diseases, despite radiological & clinical investigations, laboratory tests and function studies, the diagnosis becomes difficult. Bronchoalveolar Lavage (BAL) is a minimally invasive method in which cells are collected from bronchial and alveolar spaces for cytology. This is facilitated by using a flexible bronchoscope with which a biopsy is taken following BAL. Bronchoscopy with BAL when used appropriately can offer correct diagnosis which in turn aids in proper management of the patient. Aim: To find the concordance of BAL findings with the histopathological features of Transbronchial Lung Biopsy (TBLB) in non-neoplastic lung diseases. Materials and Methods: It was a retrospective study conducted in Kempegowda Institute of Medical Sciences, Bengaluru, Karnataka. A total of 40 patients presenting with clinico-radiological findings, suggesting a non-neoplastic lung disease in the year 2019, undergoing bronchoscopy with BAL and concurrent TBLB were chosen. The BAL fluid was processed and differential count of cells was done to classify according to the American Thoracic Society Guidelines. Concordance was checked between the diagnoses made on TBLB and BAL analysis. Results: In the present study, a total of 40 cases were included of which 13 (32.5%) cases showed neutrophilic, 16 (40%) cases showed lymphocytic, 5 (12.5%) cases showed eosinophilic and 6 (15%) cases showed normal cellular distribution on BAL cytology. Diagnoses on studying TBLB included nine cases of Nonspecific Interstitial Pneumonia, seven cases of Usual Interstitial Pneumonia, six cases of Bronchiolitis Obliterans Organising Pneumonia, three cases of Bronchiolitis, two cases each of pulmonary tuberculosis and granulomatous inflammation. There was one case each of actinomycosis, sarcoidosis, lung abscess and mucor mycosis. Normal histology was noted in seven cases. The sensitivity of BAL fluid analysis was found to be 84.84% and the concordance was 80%. The Kappa value obtained was 0.71 indicating good agreement/concordance between BAL cytology and TBLB. Conclusion: The data from the current study suggest that differential cell counts in BAL provide diagnostic information of fundamental importance in frequently occurring non-neoplastic lung diseases in the community.

Different Expression of Endothelin in the Bronchoalveolar Lavage in Patients with Pulmonary Diseases

Lung ◽  
2001 ◽  
Vol 179 (3) ◽  
pp. 163-174 ◽  
Author(s):  
F. Reichenberger ◽  
J. Schauer ◽  
K. Kellner ◽  
U. Sack ◽  
P. Stiehl ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Pulmonary Diseases

PHOSPHOLIPASIC AND PROPHOSPHOLIPASIC ACTIVITIES IN BRONCHOALVEOLAR LAVAGE FLUID IN ACUTE PULMONARY DISEASES

1981 ◽  
Vol 9 (3) ◽  
pp. 149
Author(s):  
G Offenstadt ◽  
P Pinta ◽  
J Masliah ◽  
L Alcindor ◽  
P Héricord ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Pulmonary Diseases

Fibronectin and Hyaluronan in Bronchoalveolar Lavage Fluid from Young Patients with Chronic Obstructive Pulmonary Diseases

Respiration ◽  
1995 ◽  
Vol 62 (3) ◽  
pp. 125-129 ◽  
Author(s):  
Wei Dong Song ◽  
An Cheng Zhang ◽  
Yu Ying Pang ◽  
Li Hua Liu ◽  
Jing Yun Zhao ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Bronchoalveolar Lavage Fluid ◽  
Young Patients ◽  
Lavage Fluid ◽  
Pulmonary Diseases ◽  
Chronic Obstructive ◽  
Chronic Obstructive Pulmonary Diseases

scholarly journals Bronchoalveolar lavage as a tool for evaluation of cellular alteration during Aelurostrongylus abstrusus infection in cats

2014 ◽  
Vol 34 (10) ◽  
pp. 990-995 ◽  
Author(s):  
Vitor M. Ribeiro ◽  
Joziana M.P. Barçante ◽  
Déborah Negrão-Correa ◽  
Thales A. Barçante ◽  
André Klein ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Experimental Infection ◽  
Alveolar Macrophages ◽  
Inflammatory Process ◽  
Pulmonary Diseases ◽  
Control Group ◽  
Aelurostrongylus Abstrusus ◽  
Cellular Analysis ◽  
Cell Counts ◽  
Third Stage

Bronchoalveolar lavage (BAL) is a procedure that retrieves cells and other elements from the lungs for evaluation, which helps in the diagnosis of pulmonary diseases. The aim of this study was to perform this procedure for cellular analysis of BAL fluid alterations during experimental infection with Aelurostrongylus abstrusus in cats. Fourteen cats were individually inoculated with 800 third stage larvae of A. abstrusus and five non-infected cats lined as a control group. The BAL procedure was performed through the use of an endotracheal tube on the nineteen cats with a mean age of 18 months, on 0, 30, 60, 90, 120, 180 and 270 days after infection. Absolute cell counts in the infected cats revealed that alveolar macrophages and eosinophils were the predominant cells following infection. This study shows that the technique allows us to retrieve cells and first stage larvae what provides information about the inflammatory process caused by aelurostrongylosis.

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