ScienceGate
Advanced Search
Author Search
Journal Finder
Blog
Sign in / Sign up
ScienceGate
Search
Author Search
Journal Finder
Blog
Sign in / Sign up
From Genes and Mechanisms to Molecular-Targeted Therapies: The Long Climb to the Cure of Cerebral Cavernous Malformation (CCM) Disease
Methods in Molecular Biology - Cerebral Cavernous Malformations (CCM)
◽
10.1007/978-1-0716-0640-7_1
◽
2020
◽
pp. 3-25
◽
Cited By ~ 1
Author(s):
Saverio Francesco Retta
◽
Andrea Perrelli
◽
Lorenza Trabalzini
◽
Federica Finetti
Keyword(s):
Targeted Therapies
◽
Cavernous Malformation
◽
Cerebral Cavernous Malformation
◽
Molecular Targeted Therapies
Start Chat
Download Full-text
Related Documents
Cited By
References
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies
Rare Diseases
◽
10.1080/21675511.2016.1142640
◽
2016
◽
Vol 4
(1)
◽
pp. e1142640
◽
Cited By ~ 15
Author(s):
Saverio Marchi
◽
Eliana Trapani
◽
Mariangela Corricelli
◽
Luca Goitre
◽
Paolo Pinton
◽
...
Keyword(s):
Targeted Therapies
◽
Cavernous Malformation
◽
Cerebral Cavernous Malformation
Start Chat
Download Full-text
Potential of Molecular Targeted Therapies in Childhood Brain Tumors (BRAF Inhibitors)
Klinische Pädiatrie
◽
10.1055/s-0030-1270313
◽
2010
◽
Vol 223
(01)
◽
Author(s):
S Pfister
Keyword(s):
Brain Tumors
◽
Targeted Therapies
◽
Braf Inhibitors
◽
Childhood Brain Tumors
◽
Molecular Targeted Therapies
Start Chat
Download Full-text
A Case Report and Overview of Familial Cerebral Cavernous Malformation Pathogenesis in an Adult Patient
JHN Journal
◽
10.29046/jhnj.013.2.003
◽
2018
◽
Vol 13
(2)
◽
Author(s):
Manu Arul
◽
Omaditya Khanna
◽
Michael Gooch
Keyword(s):
Case Report
◽
Adult Patient
◽
Cavernous Malformation
◽
Cerebral Cavernous Malformation
◽
Familial Cerebral Cavernous Malformation
Start Chat
Download Full-text
Faculty Opinions recommendation of The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1158058.618150
◽
2009
◽
Author(s):
W Brent Derry
◽
Shu Ito
Keyword(s):
Signaling Pathway
◽
Rho Gtpases
◽
Cavernous Malformation
◽
Cerebral Cavernous Malformation
◽
Vascular Integrity
Start Chat
Download Full-text
Faculty Opinions recommendation of Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.12892957.14181055
◽
2011
◽
Author(s):
Magdalena Goetz
Keyword(s):
Cavernous Malformation
◽
Cerebral Cavernous Malformation
◽
Vascular Pathology
Start Chat
Download Full-text
Somatic MAP3K3 mutation defines a subclass of cerebral cavernous malformation
The American Journal of Human Genetics
◽
10.1016/j.ajhg.2021.04.005
◽
2021
◽
Author(s):
Jiancong Weng
◽
Yingxi Yang
◽
Dong Song
◽
Ran Huo
◽
Hao Li
◽
...
Keyword(s):
Cavernous Malformation
◽
Cerebral Cavernous Malformation
Start Chat
Download Full-text
Risks of molecular targeted therapies to fertility and safety during pregnancy: a review of current knowledge and future needs
Expert Opinion on Drug Safety
◽
10.1080/14740338.2021.1893299
◽
2021
◽
pp. 1-19
Author(s):
Elena Lorenzi
◽
Matteo Simonelli
◽
Pasquale Persico
◽
Angelo Dipasquale
◽
Armando Santoro
Keyword(s):
Targeted Therapies
◽
Current Knowledge
◽
Molecular Targeted Therapies
◽
Future Needs
Start Chat
Download Full-text
Generation of an induced pluripotent stem cell line (UNCCi002-A) from a healthy donor using a non-integration system to study Cerebral Cavernous Malformation (CCM)
Stem Cell Research
◽
10.1016/j.scr.2021.102421
◽
2021
◽
pp. 102421
Author(s):
Alvaro A. Beltran
◽
Sarahi G. Molina
◽
Ariana Marquez
◽
Lorena J. Munoz
◽
Jose F. Olivares
◽
...
Keyword(s):
Stem Cell
◽
Cell Line
◽
Healthy Donor
◽
Pluripotent Stem Cell
◽
Cavernous Malformation
◽
Induced Pluripotent Stem Cell
◽
Cerebral Cavernous Malformation
◽
Stem Cell Line
◽
Integration System
◽
Induced Pluripotent
Start Chat
Download Full-text
Letter to the editor concerning “Liver transplantation for metastatic wild‐type gastrointestinal stromal tumor in the era of molecular targeted therapies: Report of a first case"
American Journal of Transplantation
◽
10.1111/ajt.16076
◽
2020
◽
Vol 20
(12)
◽
pp. 3701-3702
Author(s):
Margherita Nannini
◽
Maria Abbondanza Pantaleo
Keyword(s):
Liver Transplantation
◽
Gastrointestinal Stromal Tumor
◽
Targeted Therapies
◽
Stromal Tumor
◽
Wild Type
◽
Molecular Targeted Therapies
◽
Letter To The Editor
◽
First Case
Start Chat
Download Full-text
KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease
Free Radical Biology and Medicine
◽
10.1016/j.freeradbiomed.2018.04.425
◽
2018
◽
Vol 120
◽
pp. S129
Author(s):
Andrea Perrelli
◽
Eliana Trapani
◽
Cinzia Antognelli
◽
Simona Delle Monache
◽
Claudia Fornelli
◽
...
Keyword(s):
Oxidative Stress
◽
Cavernous Malformation
◽
Cerebral Cavernous Malformation
◽
Loss Of Function
Start Chat
Download Full-text
Sign in / Sign up
Close
Export Citation Format
Close
Share Document
Close